A5036046544- Hedgehog Signaling Pathway Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Cancer Cells and Metastasis
- Bone and Dental Protein Studies
- Cellular transport and secretion
- Neuroinflammation and Neurodegeneration Mechanisms
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- dental development and anomalies
- Muscle Physiology and Disorders
- Cell Adhesion Molecules Research
- Spinal Fractures and Fixation Techniques
- Cutaneous Melanoma Detection and Management
- Seaweed-derived Bioactive Compounds
- Congenital Ear and Nasal Anomalies
- Growth and nutrition in plants
- Planarian Biology and Electrostimulation
- Pelvic and Acetabular Injuries
- Skin and Cellular Biology Research
- Mast cells and histamine
- Trigeminal Neuralgia and Treatments
- Oropharyngeal Anatomy and Pathologies
- Protein Interaction Studies and Fluorescence Analysis
- Immunotherapy and Immune Responses
- Marine Sponges and Natural Products
National Institute of Research and Development for Biological Sciences
2012-2024
University of Bucharest
2014
Recently, a novel type of stromal cell - the telocytes (TC) was identified in mouse trachea. These cells are known to possess ultrastructural characteristics, which support their role intercellular signaling. We found TC all compartments tracheal wall. with long prolongations (telopodes, Tp) were lining longitudinally collagen bundles, and serially arranged (end-to-end connections Tp found). Noteworthy, frequently establish synapses mast (MC). Primary cilia also TC. In conclusion, could be...
The influence of spore concentration on the ability a Trichoderma consortium to colonize Passiflora caerulea phyllosphere was evaluated by determining effects foliar treatments with two concentrations, in repeated treatments, morphological, physiological, and ultrastructural characteristics, yield quality P. caerulea. studied crop features were related its nutraceutical use: accumulation polyphenols flavonoids, antioxidant activity, mouse fibroblast L929 cells. consisted strains, T....
Abstract TCs (telocytes) are actually defined as stromal cells with specific long and thin prolongations, called Tp (telopodes). They have been positively identified in various tissues we now report their presence the esophagus. These were by TEM (transmission electron microscopy) esophageal samples of Wistar rats ( n = 5) occurring beneath basal epithelial layer, submucosa, closely related to smooth striated muscular fibres, also adventitia. mast cells, macrophages microvessels. Hybrid...
Bacterial cellulose is a biocompatible biomaterial with unique macromolecular structure. Unlike plant-derived cellulose, bacterial produced by certain bacteria, resulting in sustainable material consisting of self-assembled nanostructured fibers high crystallinity. Due to its purity, appealing for biomedical applications and has raised increasing interest, particularly the context 3D printing tissue engineering regenerative medicine applications. can serve as an excellent bioink printing,...
Marine glycosaminoglycans (GAG) isolated from different invertebrates, such as molluscs, starfish or jellyfish, have been described unique molecules with important pharmacological applications. Scarce information is available on GAG extract Rapana venosa marine snail. The aim of this study was to isolate a R . snail and investigate its physicochemical, antioxidant antiproliferative properties for further biomedical use. morphology, chemical elemental composition the were established well...
Silver nanoparticles (AgNP) suspensions were biosynthesized by silver ions reduction in the presence of collagen, a nontoxic, organic polymer, intending to improve their medical use periodontitis treatment. Spectrophotometric measurements showed time- and concentration-dependent increase AgNP formation each suspension variant. Transmission electron microscopy revealed spherical morphology collagen mean diameter size was around 30 nm. The particle distribution zeta potential values determined...
The suburothelium has received renewed interest because of its role in sensing bladder fullness. Various studies evaluated suburothelial myofibroblasts (MFs), interstitial cells (ICs), Cajal (ICCs) or telocytes (TCs), which resulted inconsistencies terminology and difficulties understanding the structure. In order to elucidate these issues, use electron microscopy seems be an ideal choice. It was hypothesized that cell population band is heterogeneous attempt clarify above-mentioned...
The tympanic membrane (TM) integrity is of utmost importance for the sense hearing. Therefore, intrinsic potential TM to regenerate and repair deserves complete characterisation. Existing studies brought evidence on epithelial stem niche TM. However, stromal compartment was not evaluated harbouring a distinctive stem, or progenitor, niche. We aimed doing this in transmission electron microscopy. used TMs dissected out from 3 male Oryctolagus cuniculus rabbits. Evidence quiescent cells...
Dental pulp tissue was collected from 6 healthy adult patients, prior to prosthetic treatments, in order evaluate the situ phenotype of dental stromal cells and compare with that stem cells. A CD34–/CD44+/CD105–/CD117+/CD146–/nestin– core found. Cells a similar phenotype, but CD44–, were found cell richzone. networks (DPSNs) CD117+/CD44+ core, CD117+/CD44– rich zone. The c-kit-positive DPSNs contacting nerves were, this regard only, comparable interstitial Cajal Stromal signalling needs...
Neurons from sensory ganglia are exposed to oxidative attack in diabetes. Altered mitochondrial morphologies due impaired dynamics (fusion, fission) and cristae remodeling. This study aimed evaluate using transmission electron microscopy changes diabetic trigeminal suggestive for ignition of apoptosis, absence "classical" morphological signs apoptosis. We used samples (from six type 2 diabetes human donors five streptozotocin (STZ)-induced rats). In we found three main distributions...