Hichem A. Menail

ORCID: 0000-0001-6524-7547
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About
Contact & Profiles
Research Areas
  • Neurobiology and Insect Physiology Research
  • Physiological and biochemical adaptations
  • Insect and Arachnid Ecology and Behavior
  • Insect and Pesticide Research
  • Genetics, Aging, and Longevity in Model Organisms

Université de Moncton
2021-2024

Mitochondria have been suggested to be paramount for temperature adaptation in insects. Considering the large range of environments colonized by this taxon, we hypothesized that species surviving changes would those with most flexible mitochondria. We thus investigated responses mitochondrial oxidative phosphorylation (OXPHOS) three flying insects: honeybee (Apis mellifera carnica), fruit fly (Drosophila melanogaster) and Colorado potato beetle (Leptinotarsa decemlineata). Specifically,...

10.3389/fphys.2022.897174 article EN cc-by Frontiers in Physiology 2022-04-25

ABSTRACT The metabolic responses of insects to high temperatures have been linked their mitochondrial substrate oxidation capacity. However, the mechanism behind this flexibility is not well understood. Here, we used three insect species with different thermal tolerances (the honey bee, Apis mellifera; fruit fly, Drosophila melanogaster; and potato beetle, Leptinotarsa decemlineata) characterize sensitivity enzymes. Specifically, measured activity enzymes involved in glycolysis (hexokinase,...

10.1242/jeb.247221 article EN publisher-specific-oa Journal of Experimental Biology 2024-04-29

Abstract The mechanisms that underpin aging are still elusive. In this study, we suggest the ability of mitochondria to oxidize different substrates, which is known as metabolic flexibility, involved in process. To verify our hypothesis, used honey bees ( Apis mellifera carnica ) at ages, assess mitochondrial oxygen consumption and enzymatic activities key enzymes energetic metabolism well ATP5A1 content (subunit ATP synthase) adenylic energy charge (AEC). We also measured mRNA abundance...

10.1096/fj.202300654r article EN cc-by-nc-nd The FASEB Journal 2023-10-02
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