A5000089685- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Airway Management and Intubation Techniques
- Family and Patient Care in Intensive Care Units
- Simulation-Based Education in Healthcare
- COVID-19 Clinical Research Studies
- Innovations in Medical Education
- Esophageal Cancer Research and Treatment
- Health and Medical Research Impacts
- Electrolyte and hormonal disorders
- Palliative Care and End-of-Life Issues
- Health Systems, Economic Evaluations, Quality of Life
- Occupational Health and Performance
- Head and Neck Cancer Studies
- Cardiac tumors and thrombi
- Respiratory Support and Mechanisms
- Biosimilars and Bioanalytical Methods
- Healthcare professionals’ stress and burnout
- Mosquito-borne diseases and control
- Renal function and acid-base balance
- Vitamin C and Antioxidants Research
- Infrared Thermography in Medicine
- Grief, Bereavement, and Mental Health
National University Hospital
2009-2025
National University Health System
2015-2022
National University of Singapore
2019-2022
National University Cancer Institute, Singapore
2022
Thomas Jefferson University
2019
St. Marianna University School of Medicine
2015
Despite international differences in cultural perspectives on end-of-life issues, little is known of the care for dying general wards acute hospitals Asia.We performed a retrospective medical chart review all 683 adult patients who died without intensive unit (ICU) admission our Singaporean hospital 2007. We first evaluated prevalence do-not-resuscitate (DNR) orders and or against life-sustaining therapies; second, if such were discussed with and/or family members; third, actual treatments...
Abstract Coronavirus disease (COVID-19) and tuberculosis (TB) developed in 4 foreign workers living dormitories Singapore during April–May 2020. Clinical manifestations atypical radiographic features of COVID-19 led to the diagnosis TB through positive interferon-gamma release assay culture results. During pandemic, should not be overlooked.
Abstract Background Durvalumab consolidation is associated with improved survival following concurrent chemoradiotherapy (CCRT) in patients stage III non‐small cell lung cancer (NSCLC). Given the heterogeneity of NSCLC patients, this study we evaluated efficacy and safety durvalumab real‐world setting. Method Unresectable were retrospectively studied: one cohort received CCRT, another had CCRT‐durvalumab. Primary endpoints progression‐free (PFS) overall (OS), secondary relapse rate safety....
Abstract Partial anomalous pulmonary venous return (PAPVR) is a rare congenital heart condition which often asymptomatic and hence remains undiagnosed, but could occasionally be detected on thoracic imaging as an incidental finding. For cases of newly diagnosed hypertension with concurrent PAPVRs, the diagnostic workup subsequent management are more complicated, requiring thorough evaluation secondary causes hypertension, assessing relative PAPVR shunt contribution to hypertension. We herein...
Immune-related adverse events (IrAEs) of immune checkpoint inhibitors (ICIs) can be serious and unpredictable. We examine the incidence rate risk factors for IrAEs in an Asian cohort nonsmall cell lung cancer (NSCLC) patients treated with immunotherapy. Between June 2014 August 2020, we retrospectively analysed NSCLC anti-PD-1 or anti-PD-L1 at National University Cancer Institute, Singapore. A Poisson regression model was used to estimate effect on any grade IrAEs. One hundred forty-one were...
Primary resistance to immune checkpoint inhibitors (ICI) is observed in routine clinical practice. We sought determine factors predictive of primary ICI monotherapy, defined by the Society for Immunotherapy Cancer (SITC) as progression within 6 months treatment with patients receiving at least weeks advanced non-small-cell lung cancer (NSCLC).Patients stage IV NSCLC treated single-agent two tertiary hospitals Singapore were included. A multivariate logistic regression model was utilised...
On January 23, 2020, Singapore reported its first imported case of COVID-19 and within 2 weeks local cluster.1 Informed by the severe acute respiratory syndrome (SARS) experience 2003, country's leaders health authorities quickly sprang into action forming an inter-ministerial governmental agency2 to lead a coordinated national response that has gained international attention.3,4 frontline were Singapore's public care institutions, including academic medical centers. As residents provide...
Endobronchial ultrasound (EBUS) combined with trans-esophageal endoscopic bronchoscope guided fine need aspirate (EUS-B FNA) of mediastinal lymph nodes is an established procedure for diagnosis. The main barrier to a EBUS EUS-B FNA approach availability trained and accredited pulmonologist who can perform safely confidently. To address this gap, we undertook training program experienced bronchoscopists train, learn, incorporate into their procedural practice. Thirty-two patients were...
This study objectively evaluates the effectiveness of a 6-week Preparatory Training Phase (PTP) programme prior to Basic Military (BMT) for less physically conditioned conscripts in Singapore Armed Forces.We compared exercise test results group fi t recruits who underwent 16-week modified-BMT (mBMT) (consisting PTP and 10-week BMT phase) with their 'fitter' counterparts enlisted traditional direct-intake (dBMT) this prospective cohort consisting 36 subjects. The main outcome measures...
Abstract Background and objective Simulation enhances a physician's competency in procedural skills by accelerating ascent of the learning curve. Training programmes are moving away from Halstedian model ‘see one, do teach one’, also referred as medical apprenticeship. We aimed to determine if 3‐month structured bronchoscopy curriculum that incorporated simulator training could improve among pulmonary medicine trainees. Methods prospectively recruited trainees hospitals with accredited...
Like their counterparts in many other nations, physicians Singapore are tasked with providing care, conducting research, and teaching leadership to junior doctors. In this paper, we describe our experience implementing the first chief residency program Singapore. INITIATIVE: A pilot of a was initiated Department Medicine at National University Hospital July 2008, 1 resident (CR) 2 associate CR positions. The used US model for training as initial framework. CRs would assist orientation...
A previously well 55-year-old man was referred to the cardiology service with a three-month history of vague chest tightness and progressive exertional dyspnea. He in New York Heart Association (NYHA) functional class III on presentation. However, this not associated orthopnea, paroxysmal nocturnal dyspnea, or lower-limb swelling. underwent an exercise stress electrocardiogram test six weeks prior presentation, which normal up stage 4 Bruce protocol. had no significant past medical illness.
Long duty hours have been associated with significant medical errors, adverse events, and physician âburn-outâ. An innovative night float (NF) system has implemented in our internal medicine program to reduce the negative effects of long conventional full-call systems. However, concerns remain if this would result inadequate training for interns. We developed a structured questionnaire assess junior doctorsâ perceptions NF compared full calls, areas patient safety, training,...
Convex probe endobronchial ultrasound transbronchial needle aspirations (CP-EBUS-TBNAs) and radial lung biopsies (RP-EBUS-TBLBs) can be performed under moderate sedation or general anesthesia. Moderate is more convenient, however patient discomfort may result in inadequate tissue sampling. General anesthesia ensures better cooperation but requires logistics also carries risks. We aim to describe the diagnostic yield safety of CP-EBUS-TBNAs RP-EBUS-TBLBs when at our center. All patients who...
Spontaneous regression (SR) of lung cancer is especially rare. We report a case an early endobronchial squamous cell carcinoma that exhibited complete radiologic and pathologic SR soon after diagnosis. The patient was monitored radiologically bronchoscopically at regular intervals to date, the biopsy samples have been negative. Remarkably, has maintained 6 years diagnosis, without local recurrence or distant metastases. Many hypotheses abound explain how achieved despite lack treatment.
Copyright © 2016 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
Copyright © 2016 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.