A5033538734- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Diabetes and associated disorders
- Genetic Associations and Epidemiology
- IL-33, ST2, and ILC Pathways
- Endoplasmic Reticulum Stress and Disease
- Pancreatic function and diabetes
- Lymphatic System and Diseases
- Neonatal Respiratory Health Research
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Immunotherapy and Immune Responses
Joslin Diabetes Center
2022
Harvard University
2014-2022
Dana-Farber Cancer Institute
2014
Boston University
2014
Infusion of lymph node–derived fibroblastic reticular cells into septic mice increases survival at late time points after disease onset.
CD5 is constitutively expressed on all T cells and a negative regulator of lymphocyte function. However, the full extent function in immunity remains unclear. deficiency impacts thymic selection extra-thymic regulatory cell generation, yet knockout was reported to cause no immune pathology. Here we show that key modulator gut immunity. We generated mice with inducible knockdown (KD) autoimmune-prone nonobese diabetic (NOD) background. caused cell-dependent wasting disease driven by chronic...