Changjin Lee

ORCID: 0000-0001-6560-994X
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About
Contact & Profiles
Research Areas
  • Cytokine Signaling Pathways and Interactions
  • Immune cells in cancer
  • Ectopic Pregnancy Diagnosis and Management
  • Skin and Cellular Biology Research
  • Cancer-related gene regulation
  • Liver Disease and Transplantation
  • Immune Cell Function and Interaction
  • Peptidase Inhibition and Analysis
  • Infectious Aortic and Vascular Conditions
  • Cell death mechanisms and regulation
  • Digestive system and related health
  • Central Venous Catheters and Hemodialysis
  • Cellular Mechanics and Interactions
  • Cardiovascular Function and Risk Factors
  • Aortic aneurysm repair treatments
  • S100 Proteins and Annexins
  • Maternal and Perinatal Health Interventions
  • Pulmonary Hypertension Research and Treatments
  • Maternal and fetal healthcare

CHA Bundang Medical Center
2023

CHA University
2021-2023

Seoul National University
2015

Although SWI3-related gene (SRG3), a chromatin remodeling factor, is critical for various biological processes including early embryogenesis and thymocyte development, it unclear whether SRG3 involved in the differentiation of CD4+ T cells, key mediator adaptive immune responses. Because known that experimental autoimmune encephalomyelitis (EAE) development determined by activation helper here, we investigated role EAE using transgenic mouse models exhibiting two distinct expression...

10.1371/journal.pone.0132329 article EN cc-by PLoS ONE 2015-07-06

Abstract Profilin-1 (PFN1) regulates actin polymerization and cytoskeletal growth. Despite the essential roles of PFN1 in cell integration, its subcellular function keratinocyte has not been elucidated yet. Here we characterize specific regulation DNA damage response repair machinery. depletion accelerated damage-mediated apoptosis exhibiting PTEN loss instigated by increased phosphorylated inactivation followed high levels AKT activation. changed predominant cytoplasmic localization to...

10.1007/s11033-021-06210-6 article EN cc-by Molecular Biology Reports 2021-02-01

Background: Liver transplantation (LT) increases the heart and vessel workload in patients with cirrhotic cardiomyopathy. While interaction of left ventricle (LV) arterial system (ventriculoarterial coupling, VAC) is a key determinant cardiovascular performance, little known about changes VAC after LT. Therefore, we evaluated relationship between LT outcomes. Methods: 344 consecutive underwent echocardiographic assessments before within 30 days Non-invasive elastance (Ea), LV end-systolic...

10.4097/kja.23266 article EN cc-by-nc Korean journal of anesthesiology 2023-07-12

Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality. Twin pregnancy cesarean delivery are well-known risk factors for PPH. However, few studies have investigated PPH in mothers who undergone twin pregnancies. Therefore, this study the associated with severe after pregnancies.We searched reviewed Korean Health Insurance Review Assessment Service's claims data from July 2008 to June 2021 using code corresponding pregnancy. Severe was defined as requiring red...

10.17085/apm.23019 article EN cc-by-nc Anesthesia and Pain Medicine 2023-08-08
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