A5025519442- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Insect symbiosis and bacterial influences
- Parasites and Host Interactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Resistance in Bacteria
- Reproductive tract infections research
- Insects and Parasite Interactions
- Parasite Biology and Host Interactions
- Antibiotic Use and Resistance
- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Malaria Research and Control
- Cervical Cancer and HPV Research
- Bacterial Identification and Susceptibility Testing
- Biochemical and Molecular Research
- Adolescent Sexual and Reproductive Health
- Streptococcal Infections and Treatments
- Infections and bacterial resistance
- Pelvic floor disorders treatments
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- HIV/AIDS oral health manifestations
University of Nottingham
2018-2024
Queen's Medical Centre
2023-2024
University of Ghana
2016-2019
Korle Bu Teaching Hospital
2019
University of Health and Allied Sciences
2016-2018
Research Center Borstel - Leibniz Lung Center
2018
Bloodstream infections (BSI) are life-threatening emergencies. Identification of the common pathogens and their susceptibility patterns is necessary for timely empirical intervention. We conducted a 4-year retrospective analysis blood cultures from all patients excluding neonates at Korle-Bu Teaching hospital, Ghana, January 2010 through December 2013. Laboratory report data were used to determine BSI, culture contamination, pathogen profile, antimicrobial resistance patterns. Overall, 3633...
This study was designed to investigate whether household cockroaches harbor cephalosporin-resistant enterobacteria that share resistance determinants with human inhabitants. From February through July 2016, whole cockroach homogenates and fecal samples from 100 households were cultured for (CRe). The CRe examined plasmid-mediated AmpC, ESBL, carbapenemase genes; antibiotic susceptibility patterns; conjugative transfer of mechanisms. Clonal associations between determined by multi-locus...
As part of malaria characterization study in the South-Tongu district Ghana, current was conducted to explore relationships between malaria, schistosomiasis, soil transmitted helminths and malnutrition riparian community settings that had hitherto encountered episodes mass deworming exercises. School-age children were enrolled a cross-sectional from April through July 2012. Stool urine samples examined respectively for Schistosoma haematobium. Blood analyzed parasites haemoglobin (Hb)...
Animal African trypanosomiasis (AAT) is a severe, wasting disease of domestic livestock and diverse wildlife species. The in cattle kills millions animals each year inflicts major economic cost on agriculture sub-Saharan Africa. Cattle AAT caused predominantly by the protozoan parasites Trypanosoma congolense T. vivax, but laboratory research pathogenic stages these organisms severely inhibited difficulties making even minor genetic modifications. As result, many important basic questions...
Trypanosomatid parasites undergo developmental regulation to adapt the different environments encountered during their life cycle. In Trypanosoma brucei, a genome wide selectional screen previously identified regulator of protein family ESAG9, which is highly expressed in stumpy forms, morphologically distinct bloodstream stage adapted for tsetse transmission. This regulator, TbREG9.1, has an orthologue congolense, despite absence morphotype that parasite species, important cause livestock...
Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, main cause of which the protozoan parasite Trypanosoma congolense . In comparison to well-studied T brucei , there major paucity knowledge regarding biology Here, we use combination omics technologies and novel genetic tools characterise core metabolism in mammalian-infective bloodstream-form parasites, test whether metabolic differences compared impact upon sensitivity inhibition....
There is little data on Trichomonas vaginalis infection in Ghana. This study evaluated the prevalence of trichomoniasis using different diagnostic methods and determined risk factors for patients. A structured questionnaire was administered. Vaginal swabs, urethral swabs urine specimens were obtained from consenting patients; samples processed following standard protocols. The presence T. wet mount microscopy polymerase chain reaction (PCR) as gold standard. We also assessed performance JD's...
The complexity of periodontitis in both etiology and progression has raised many questions, necessitating enormous research recent years. aim the present study was to detect presence herpes viruses Ghanaian patients diagnosed with periodontitis.Thirty-one were included study; 21 classified into localized chronic, generalized, aggressive periodontitis, 10 without disease used as controls. Subgingival samples collected, followed by DNA extraction. Multiplex polymerase chain reaction amplify...
Trichomonas vaginalis (TV) infection is the most prevalent non-viral sexually transmitted pathogen worldwide. Among pregnant women, may cause adverse birth outcomes such as premature rupture of membranes and labour. In view paucity information relating to TV among Ghanaian this study investigated its prevalence associated co-infections women. High vaginal swabs were obtained from 99 women using sterile cotton swab sticks. Wet preparation, Grams staining, culturing, coagulase sensitivity...
ABSTRACT Aim Household insect pests, including cockroaches, have gained consideration as potential vectors for multidrug resistant pathogens of public health concern. This study was designed to investigate whether household cockroaches share beta-lactam resistance determinants with human inhabitants. Methods From February through July 2016, 400 were systematically collected from 100 households. Whole homogenates and faecal samples inhabitants all included households cultured...
Abstract Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, main cause of which the protozoan parasite Trypanosoma congolense . In comparison to well-studied T. brucei , there major paucity knowledge regarding biology Here, we use combination omics technologies and novel genetic tools characterise core metabolism in mammalian-infective bloodstream-form parasites, test whether metabolic differences compared impact upon drug...
Abstract Trypanosomatid parasites undergo developmental regulation to adapt the different environments encountered during their life cycle. In Trypanosoma brucei , a genome wide selectional screen previously identified regulator of protein family ESAG9, which is highly expressed in stumpy forms, morphologically distinct bloodstream stage adapted for tsetse transmission. This regulator, TbREG9.1, has an orthologue congolense despite absence morphotype that parasite species, important cause...