A5004903282- Chronic Obstructive Pulmonary Disease (COPD) Research
- Autoimmune and Inflammatory Disorders Research
- Inflammatory Myopathies and Dermatomyositis
- Lung Cancer Treatments and Mutations
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Genetic and Environmental Crop Studies
- Eosinophilic Disorders and Syndromes
- Immunodeficiency and Autoimmune Disorders
- Vaccine Coverage and Hesitancy
- Immune Cell Function and Interaction
- Agricultural pest management studies
- Pregnancy and preeclampsia studies
- Public Health and Nutrition
- Cancer Genomics and Diagnostics
- Asthma and respiratory diseases
- Systemic Lupus Erythematosus Research
- Mindfulness and Compassion Interventions
- Inflammasome and immune disorders
- Thermal Regulation in Medicine
- Healthcare Policy and Management
- IL-33, ST2, and ILC Pathways
- Inflammation biomarkers and pathways
- Maternal and Perinatal Health Interventions
- Toxin Mechanisms and Immunotoxins
Indian Institute of Science Bangalore
2025
Johns Hopkins Medicine
2023-2024
Johns Hopkins University
2023-2024
Baba Raghav Das Medical College
2023
All India Institute of Medical Sciences
2023
King George's Medical University
2018-2021
Sardar Patel Medical College
2021
The University of Texas Southwestern Medical Center
2020
Southwestern Medical Center
2020
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2013-2018
Patients with a systemic autoimmune rheumatic disease (AIRD) are vulnerable to SARS Cov-2 infection. Vaccination against this infection can prevent the patients from developing severe disease. But vaccine hesitancy in group emerge as hurdle. So there is need understand perception regarding vaccination AIRD patients. The study an interview-based survey done and control general population. questionnaire included subject's demographic details, duration, diagnosis, activity of AIRD, questions...
Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (EUCAST) are now being used in many countries. This study was planned to ascertain the agreement antimicrobial susceptibility using Clinical and Laboratory Standards Institute (CLSI) EUCAST breakpoints during Kirby-Bauer disk diffusion method. a prospective observational study. isolates belonging family Enterobacteriaceae recovered between January December, 2022, were included analysis. The diameter of zone...
Winged bean (Psophocarpus tetragonolobus (L.) DC.) is a potential legume crop of the tropics with high protein and oil content in seeds. Analysis mutual genotypic relationships among twenty four genotypes P. through Mantel test found significant correlation (r = 0.839) between similarity matrices results obtained from use RAPD ISSR molecular markers. The UPGMA tree based on Jaccard's coefficient generated their cumulative data showed two distinct clusters seven sub-clusters these accessions....
Summary Gut microflora and dysbiosis as an environmental factor has been linked to the pathogenesis of enthesitis-related arthritis (JIA-ERA); thus, we performed a proof-of-concept study probiotics modulate gut-flora effects on immune clinical parameters children having JIA-ERA. Forty-six with active JIA-ERA were randomized placebo or probiotic therapy along non-steroidal anti-inflammatory drugs (NSAIDs) for 12 weeks. Patients assessed using six-point composite disease activity index...
The xenogeneic silencer protein Lsr2 from Mycobacterium tuberculosis plays a critical role in its survival and pathogenesis. is nucleoid-associated that interacts with DNA vivo regulates many genes. Purified forms nucleoprotein filaments molecules leading to highly compacted conformations. However, the physical mechanism underlying Lsr2-mediated compaction, resulting gene regulation, remains elusive. We employed combination of biochemical assay, single-molecule imaging, molecular dynamics...
Probiotics have been shown to be useful for the treatment of many disease conditions. These beneficial effects are believed mediated by change in composition gut microbiota and modulation host immune responses. However, available data on effect probiotics these parameters quite limited. We studied fecal microbiota, using 16S rRNA sequencing, responses peripheral blood (plasma cytokine levels, T cell subsets vitro production after stimulation with anti-CD3/CD28 antibody or lipopolysaccharide)...
Lung cancer is the most common type of worldwide with an estimation 1.82 million new cases diagnosed; and it leading cause cancer-related deaths. Epidermal growth factor receptor (EGFR) a tyrosine kinase identified as being highly expressed in cells including lung cancers. The aim study to determine EGFR mutation status non-small cell (NSCLC) patients investigate association between clinicopathological characters patients.The tissue samples were collected bronchoscopically. mutations 70...
Objectives Urinary biomarkers may help in identification, treatment and assessment of response patients with lupus nephritis (LN). Osteoprotegerin (OPG) is produced by the kidneys lymphoid cells reflect renal disease activity better. The data on its utility are sparse. Methods Fifty-eight active LN (AN), 24 non-renal (ANR) 39 inactive (ID) were included. Median duration was 32 (1–204) months median age 27 (12–50) years. AN followed up every three for one year. Urine serum samples collected...
INTRODUCTION: Women face significant barriers to care related their roles as caretakers; in a prior survey, up 20% report foregoing because of difficulties with child care. We describe how lack impacts access health and determine patient interest hospital-based day center. METHODS: This is non-regulated cross-sectional survey 300 women reproductive age attending Parkland Health & Hospital System (PHHS) clinics. Outpatient clinics sampled included: Primary Care, Obstetrics Gynecology,...
Lung cancer is characterized by uncontrolled cell growth of the lung tissues. It leading cause cancer-related deaths worldwide.The study aimed to determine circulating CRP, TNF-α, IL-6 and IL-8 levels in healthy control also established association between these biomarkers with smoking status as well stages disease.51 patients 51 controls were enrolled this case-control study. The serum measured groups.The significantly higher when compared controls(P<0.0001). stage iii/iv i/ii(P<0.001)....
Abstract Background Childcare needs are an understudied social determinant of health. The effect childcare on access to healthcare must be understood inform health system interventions and policy reform. This study sought characterize needs, childcare, prior experience with navigating in settings among women a safety-net population. Methods We conducted cross-sectional patient-reported survey data collected in-person between April October 2019. Surveys were administered waiting rooms...
Objective. Monocytes of children with enthesitis-related arthritis (ERA) show Toll-like receptor 4 (TLR4) overexpression. Tenascin-C (TNC) is an extracellular matrix glycoprotein and acts as endogenous TLR4 ligand. Thus, we studied the serum synovial fluid (SF) levels TNC in ERA. Methods. was measured 80 ERA satisfying International League Associations for Rheumatology criteria. Fifteen were followed up while being treated regular nonsteroidal antiinflammatory drug (NSAID) therapy reassessed...
Background: Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide. Anemia seen as a common comorbidity in COPD patients associated with reduced functional capacity, impaired quality life, greater likelihood hospitalization, early mortality. The aim to study the prevalence anemia its association different parameters. Materials Methods: In present case–control study, 150 stable were enrolled from Outpatient Department Respiratory Medicine,...
Objective: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Systemic inflammation oxidant/antioxidant imbalance has been seen to play key role in pathogenesis COPD. The present study investigated the levels inflammatory antioxidant/oxidative stress biomarker COPD patients healthy subjects. Materials Methods: enrolled seventy controls from Department Respiratory Medicine at tertiary care hospital. Vitamin D, C-reactive protein (CRP),...
Lung cancer is considered as the most commonly diagnosed cancer. It leading cause of cancer-related mortality. Smoking and environmental pollutants act important risk factors in majority lung cases (80%-90%).This a hospital-based study carried on patients North India. Demographic profile was recorded. Hematological biochemical profiles healthy controls were compared.Highest proportion found age group 46-60 years. seen highest number male gender (76.63%) also those belonging to rural category...
Background: Exacerbations in Chronic obstructive pulmonary disease (COPD) have a considerable impact on morbidity, mortality, and quality of life. Procalcitonin (PCT) polypeptide normally produced neuroendocrine cells the thyroid lungs is marker systemic inflammation bacterial infection. Objectives: The aim this study was to determine levels PCT serum acute exacerbation COPD patients (AECOPD) stable North Indian population. Materials Methods: conducted 80 AECOPD respiratory medicine...