Previous studies have demonstrated that low skeletal muscle mass is related to decreased lung function in patients with chronic obstructive pulmonary disease. However, there little information about the relationship between and asymptomatic adults without clinically apparent disease.This was a cross-sectional study of 240,562 Korean known All subjects underwent both test (PFT) bioelectrical impedance analysis health checkup program at Kangbuk Samsung Hospital. Skeletal index (SMI) estimated...

Abstract In contrast to obesity, studies on the relationship between underweight and pulmonary function are still sparse. Thus, objective of this study was investigate effect being in a general population without apparent lung disease. A total 282,135 retrospective cohort subjects January 2012 December 2014 Korea were included. Using multivariate-adjusted analysis, body mass index (BMI) assessed. Underweight individuals represented 5.5% (n = 282,135), with most (87.9%) them females. Compare...

To investigate the factors affecting prognosis of extracorporeal shockwave therapy (ESWT) for chronic refractory Achilles tendinopathy (AT).Thirty-six patients (48 consecutive feet) with AT (>6 months) and who underwent ESWT 'poor' or 'fair' grade in Roles-Maudsley Score (RMS) after unsuccessful conservative treatment were included present study. A maximum 12 sessions conducted until success: RMS reached 'good' 'excellent'. Termination no response, was regarded as failure. Immediate outcome,...

Ultrasound is an essential tool for diagnosing shoulder disorders. However, the role of ultrasound in assessing and adhesive capsulitis has not been fully studied.To evaluate features estimate correlations between clinical impairment parameters.Case series; Level evidence, 4.A total 61 patients with clinically diagnosed unilateral were retrospectively reviewed using high-resolution ultrasound. To compare parameters, we performed examinations on both affected unaffected shoulders. including...

Abstract Background A gut–muscle axis through which the microbiome influences skeletal muscle has been hypothesized. However, sex‐specific association between characteristics of gut microbiota and mass not yet reported. Herein, we performed analyses faecal composition for in a population‐based cohort. Methods We collected samples 1052 middle‐aged participants (621 men 431 women) who attended health screenings, analysed intestinal using 16S rRNA gene sequencing. Relative was calculated...

We attempted to examine the relationship between abnormal findings on high-resolution manometry (HRM) and videofluoroscopic swallowing study (VFSS) of pharynx upper esophageal sphincter (UES), identify risk factors for aspiration.We performed VFSS HRM same day in 36 ischemic stroke patients (mean age, 67.5 years) with dysphagia. Pressure (basal, median intra bolus, nadir), relaxation time interval UES, mesopharyngeal hypopharyngeal contractility (as a contractile integral) were examined...

Objectives To evaluate the association between high-sensitivity C-reactive protein (hs-CRP) and sarcopenic obesity, to determine age or sex differences underlying relationship hs-CRP obesity. Design Observational study. Participants The study included 237 838 participants whose body composition were analysed at two health promotion centres in South Korea. divided into four groups based on composition: normal, obesity only, sarcopenia only Primary measures levels of proportion with high (≥1.0...

Vitamin C, one of essential micronutrients, has been reported to modulate the humoral immune responses in some mammals. We investigated whether vitamin C might this response mice by directly affecting B cells. Splenic cells were isolated and activated CD40- cell receptor-ligation vitro. The cultured with a pretreatment from 0 1 mM concentrations. slightly increased apoptosis dose-dependently behaved as an antioxidant. found that vivo administration intraperitoneal injection affected isotype...

To investigate the long-term effect of low-energy extracorporeal shock wave therapy (ESWT) for plantar fasciitis (PF) according to ultrasonography (US) findings.Thirty feet 25 patients with clinical diagnosis PF were enrolled and divided into two groups (Apparent-US Uncertain-US) US findings, such as fascia thickening or hypoechogenicity. Inclusion criteria symptom duration >6 months a fair poor grade in Roles-Maudsley score (RMS). ESWT (0.10 mJ/mm(2), 600 shocks) was given once week 6...

The introduction of high-resolution manometry (HRM) offered an improved method to objectively analyze the status pharynx and esophagus. At present, HRM for patients with oropharyngeal dysphagia has been poorly studied. We aimed determine feeding predict development aspiration pneumonia in using HRM.We recruited 120 who underwent both videofluoroscopic swallow study. was used estimate pressure events from velopharynx (VP) upper esophageal sphincter (UES). Feeding methods were determined...

Background Previous outcome studies for extracorporeal shock wave therapy (ESWT) have included clinically diagnosed greater trochanteric pain syndrome (GTPS). The purpose of this study is to investigate ESWT on GTPS with gluteal tendinopathy documented by magnetic resonance imaging (MRI). Methods Medical records 38 consecutive patients were retrospectively reviewed, who underwent MRI-documented (> 6 months). was conducted (1/week) when the Roles-Maudsley score (RMS) showed "Poor" or "Fair"...

Background: Homocysteine has been drawing attention with a closed linkage skeletal muscle. However, the association of hyperhomocysteinemia decreased muscle mass remains unclear. We aimed to investigate low (LMM) in asymptomatic adults.Methods: This was cross-sectional study 114,583 community-dwelling adults without cancer, stroke, or cardiovascular diseases who underwent measurements plasma homocysteine and body composition analysis from 2012 2018. Hyperhomocysteinemia defined as >15...

Abstract The relationship between hyperhomocysteinemia (HHcy) and obesity with low skeletal muscle mass (LMM) has not been established. We aim to assess the association HHcy coexistence of LMM in asymptomatic adult population. conducted a population-based cross-sectional study among individuals who underwent measurements plasma homocysteine body composition analysis. was defined as > 15 umol/L, index ≥ 25 (kg/m 2 ), less than SD below sex-specific mean young adults. participants were...

We investigated the sex-specific association between ferritin and adverse body composition in adults aged over 50 years a population-based cohort. A total of 25,546 participants (16,912 women; 8634 men) were stratified into three groups by tertiles ferritin. The number compositions was categorized as 0 (without osteopenia/osteoporosis, low muscle mass, or obesity), 1 (having one components), 2 (two), 3 (all three; osteosarcopenic obesity). As tertile increased, prevalence one, two,...

To compare swallowing function between healthy subjects and patients with pharyngeal dysphagia using high resolution manometry (HRM) to evaluate the usefulness of HRM for detecting dysphagia.Seventy-five 28 were included in this study. Diagnosis was confirmed by a videofluoroscopy. performed measure pressure timing information at velopharynx (VP), tongue base (TB), upper esophageal sphincter (UES). parameters compared groups. Optimal threshold values significant determined.VP maximal...

Mesenchymal stem cells (MSCs) of human origin have been frequently applied to experimental animal models evaluate their immunomodulatory functions.MSCs are known be activated by cytokines from T cells, predominantly interferon-γ (IFN-γ), in conjunction with other such as tumor necrosis factor-α (TNF-α) and interlukin-1β.Because IFN-γ is not cross-reactive between mouse species, the manner which MSCs administered animals stimulated function has questioned.In present study, we established...

Objective To evaluate the effects of zolpidem on functional recovery in a rat model acute ischemic stroke. Methods Following stroke procedures, 42 rats (six each group) were randomly assigned to receive (0.1, 0.25, 0.5, 1.0, 2.0 or 4.0 mg/kg) normal saline administer intraperitoneally once daily for two weeks. Motor behavioural index (MBI) scores, radial 8-arm maze (RAM) test times and brain MRI scans obtained 24 hours (Day 1) weeks 14) post-procedure. Immunohistochemistry was performed Day...

Background and Objectives: The study aimed to establish the threshold values prevalence of sarcopenia investigate association with metabolic syndrome in an urban Korean population. Materials Methods: included 300,090 adults who underwent anthropometric analyses by bioelectrical impedance analyzer. Sarcopenia was defined as: (1) class I, skeletal muscle mass index (SMI) within −1 −2 standard deviations (SDs); (2) or II, <−2 SD SMI a young Results: Low levels for I II were 39.8 36.7% men, 35.5...

It is difficult to clarify whether small deep infarction caused by cardioembolism or intrinsic vessel disease in patients with atrial fibrillation (AF). The purpose of this study was determine preexisting would differ according the presenting infarct pattern and factors associated acute single stroke AF.Between January 2008 August 2012, 1,592 consecutive ischemic within 7 days symptom onset were entered a prospectively maintained registry. For present study, 231 AF enrolled irrespective...

Objectives. We attempted to determine the propensity for sidedness of cardiogenic emboli associated with atrial fibrillation (AF) by comparing sides on which microembolic signals (MES) were detected via transcranial Doppler (TCD) monitoring and location infarcts magnetic resonance imaging. Design. Patients AF Holter MES TCD selected from an ischemic stroke registry. prosthetic valves or cerebral/carotid artery stenosis excluded. Results. By 30 patients, 78 detected: 47 right 31 left side...