- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Radiation Dose and Imaging
- Connexins and lens biology
- Effects of Radiation Exposure
- Ophthalmology and Visual Impairment Studies
- Ophthalmology and Eye Disorders
- Retinal Imaging and Analysis
- Metabolomics and Mass Spectrometry Studies
- Ocular and Laser Science Research
- Proteoglycans and glycosaminoglycans research
- Cerebral Venous Sinus Thrombosis
- Traumatic Ocular and Foreign Body Injuries
- Cell Adhesion Molecules Research
- Herpesvirus Infections and Treatments
- Neurofibromatosis and Schwannoma Cases
- Ocular Surface and Contact Lens
- Acne and Rosacea Treatments and Effects
- Ubiquitin and proteasome pathways
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Optical Coherence Tomography Applications
- Retinal and Optic Conditions
Wills Eye Hospital
2006-2024
Thomas Jefferson University
2006-2024
University of California, Los Angeles
2024
Stanford University
2024
Center for Devices and Radiological Health
2024
RAND Corporation
2024
United States Food and Drug Administration
2024
University of Miami
2013-2023
Veterans Health Administration
2012-2023
Miami VA Healthcare System
2011-2022
Erythropoietin (EPO) plays an important role in the brain's response to neuronal injury. Systemic administration of recombinant human EPO (rhEPO) protects neurons from injury after middle cerebral artery occlusion, traumatic brain injury, neuroinflammation, and excitotoxicity. Protection is part mediated by antiapoptotic mechanisms. We conducted parallel studies rhEPO a model transient global retinal ischemia induced raising intraocular pressure, which clinically relevant for diseases....
The eyes of a prospective cohort 8,607 Chernobyl clean-up workers (liquidators) were assessed for cataract at 12 and 14 years after exposure. prevalence strictly age-related cataracts was low, as expected (only 3.9% had nuclear either examination), since 90% the younger than 55 age first examination. However, posterior subcapsular or cortical characteristic radiation exposure present in 25% subjects. data Stage 1 cataracts, specifically revealed significant dose response. When various end...
Introduction This retrospective consecutive case series examined whether training on a surgical simulator reduces intraoperative complication rates among novice ophthalmology residents learning cataract surgery. Methods Beginning July 2014, the Eyesi became mandatory for postgraduate year 3 before live surgery at our institution. Complication of 11 simulator-trained (study group) were compared with their immediate simulator-naive predecessors (comparison group). Only straightforward cases...
It is important to know whether the human population includes genetically predisposed radiosensitive subsets. In vitro studies have shown that cells from individuals homozygous for ataxia telangiectasia (A-T) are much more than unaffected individuals. Although heterozygous ATM gene ( +/− ) may be slightly in , it remained determined greater susceptibility of translates into an increased sensitivity late effects vivo though there a suggestion radiotherapy patients at risk developing normal...
We identified 298 metabolites in pseudoexfoliation (PEX) glaucoma, primary open angle glaucoma (POAG) and non-glaucomatous controls. Machine learning can classify aqueous humor into the three distinct categories presents opportunity for future predictions.
Chumak, V. V., Worgul, B. Kundiyev, Y. I., Sergiyenko, N. M., Vitte, P. Medvedovsky, C., Bakhanova, E. Junk, A. K., Kyrychenko, O. Y., Musijachenko, Sholom, S. Shylo, A., P., Xu, S., Xue, X. and Shore, R. Dosimetry for a Study of Low-Dose Radiation Cataracts among Chernobyl Clean-up Workers. Radiat. Res. 167, 606– 614 (2007).A cohort 8,607 Ukrainian clean-up workers during 1986–1987 was formed to study cataract formation after ionizing radiation exposure. eligibility required the...
This study was designed to evaluate the refractive outcomes of combined cataract extraction and glaucoma surgery.Retrospective case series.A retrospective chart review patients undergoing simultaneous with trabeculectomy or drainage device surgery performed. The main outcome measure evaluated whether not spherical equivalent -1.00 +0.50 D achieved at 3 6 months postoperatively. Secondary included: reduction in intraocular pressure, amount cylinder induced by surgery, individual patient...
PURPOSE: To evaluate the refractive and surgical outcomes of cataract surgery with toric intraocular lens (IOL) implantation performed at a teaching institution. SETTING: Miami Veterans Affairs Medical Center, Miami, Florida, USA. DESIGN: Retrospective case series. METHODS: All data were obtained by retrospective chart review entered into standard computerized database for analysis. Main outcome measures included after Acrysof IOL placement, including deviation from expected spherical...
Blepharoconjunctivitis is the commonest manifestation of ocular rosacea. Cilia epilation proves Demodex folliculorum, considered an etiologic factor in Complications and differential diagnosis include dry eyes, seborrheic, bacterial allergic blepharoconjunctivitis. Treatment involves lid scrubs mercury ointment, its duration limited to 6 weeks under frequent control due corneal toxicity mercury.30-year-old female with complaint red, irritated eyes for 21 years, resistant antibiotics...
Precis: A survey among members of the American Glaucoma Society (AGS) and Optometry Association (AOA) on tonometer preference disinfection indicates a shift to disposable tips compared with 1987. Purpose: This survey’s purpose was determine how eye care providers responded 2008 Centers Disease Control (CDC) guidelines, which recommend 10% hypochlorite (dilute bleach) for reusable tonometers. Tonometers measure pressure when they touch cornea, an essential part examination. Methods: AGS AOA...