- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Skin and Cellular Biology Research
- Retinal and Macular Surgery
- Ophthalmology and Eye Disorders
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Retinopathy of Prematurity Studies
- Ocular Surface and Contact Lens
- Cancer-related Molecular Pathways
- Nuclear Structure and Function
- Diversity and Career in Medicine
- Nasolacrimal Duct Obstruction Treatments
- Ocular Infections and Treatments
- Cancer Genomics and Diagnostics
- Ocular Diseases and Behçet’s Syndrome
- Pharmaceutical industry and healthcare
- Acute Ischemic Stroke Management
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Cancer Cells and Metastasis
- Patient Satisfaction in Healthcare
University of Miami
2017-2024
Research Network (United States)
2023
Research to Prevent Blindness
2023
Creative Commons
2023
Yahoo (United Kingdom)
2023
Impact
2023
University of Miami Health System
2021
Bruce W. Carter VA Medical Center
2020
Palm Beach Neurology
2019
Stony Brook University
2008-2019
Background: The goal of the present study was to analyze macular microvacular network in mild cognitive impirment (MCI) and Alzheimer disease (AD). Methods: Twelve patients with AD 19 MCI were recruited together 21 cognitively normal controls a similar range ages. Optical coherence tomography angiography used image retinal microvascular at region, including vascular (RVN), superficial plexus (SVP), deep (DVP). Fractal analysis (box counting, D box ) representing density performed different...
Abstract Keratins that are overexpressed selectively in human carcinomas may offer diagnostic and prognostic utility. In this study, we show high expression of keratin-17 (K17) predicts poor outcome patients with cervical cancer, at early or late stages disease, surpassing accuracy either tumor staging loss p27KIP1 as a negative marker setting. We investigated the mechanistic basis for biologic impact K17 through loss- gain-of-function experiments cervix, breast, pancreatic cancer cells....
Abstract Although the overall five-year survival of patients with pancreatic ductal adenocarcinoma (PDAC) is dismal, there are differences between cases clinically and pathologically indistinguishable characteristics, suggesting that uncharacterized properties drive tumor progression. Recent mRNA sequencing studies reported gene-expression signatures define PDAC molecular subtypes correlate in survival. We previously identified Keratin 17 (K17) as a negative prognostic biomarker other cancer...
Background: A detailed analysis of the tomographic thickness intraretinal layers may provide more information on neurodegeneration in patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Objective: The goal was to analyze patterns AD andMCI. Method: Forty-nine (25 24 MCI) 21 cognitively normal (CN) controls were imaged using ultra-high-resolution optical coherence tomography obtain volumetric data centered fovea. segmented retinal nerve fiber layer (RNFL), ganglion...
Purpose. Project Shake-It-Up provided a health promotion and capacity building program for individuals with spinal cord injury, multiple sclerosis, related neurological impairments. Major research aims were to evaluate changes in participants' self-efficacy, ability set/achieve goals, perceived independent-living status.Methods. Participants completed self-efficacy measures at baseline, completion, 6- 12-month follow-up, set and/or independent living goals. Progress toward goal attainment...
In this paper we create indices of resilience to identify adolescents at risk smoking, drinking alcohol, and using illegal drugs. Using data from the National Longitudinal Study Adolescent Health, three manifestations were identified: overall-resilience, self/family-resilience, self-resilience. Our analysis reveals that overall-resilient less likely engage in risky behaviors. The self/family resilient more behaviors, but consumed less. self-resilient had reduced for smoking alcohol elevated...
This cross-sectional research explored the relationships between active engagement in life activities (leisure, social, and instrumental of daily living) quality for seniors aged 65 older residing assisted living facilities. It is increasingly recognized that participation diverse physical, cognitive, social can promote adults' life, including physical mental health, but there limited information about this population residents estimated are one million adults facilities, making facilities a...
The main aim of this study was to evaluate the safety and efficacy diode laser transscleral cyclophotocoagulation (TSCPC) in eyes with good visual acuity.A retrospective chart review identified patients who underwent TSCPC for uncontrolled intraocular pressure (IOP) from 2014 2016. Enrollment criteria included pretreatment best-corrected acuity (BCVA) 20 40 or better, a minimum 6 months postoperative follow-up.Thirty-three 33 patients(mean age, 72.1±16.0 y) were enrolled (mean follow-up...
Purpose: The purpose of this study was to investigate the association between corneal densitometry (CD) values from Scheimpflug tomography imaging, severity guttae, and visual acuity in eyes with Fuchs endothelial dystrophy (FECD). Methods: This a retrospective, cross-sectional study. Patients FECD were examined at Bascom Palmer Eye Institute January 2015 September 2019. We extracted CD central annuli 0-2, 2-6, 6-10 10-12 mm images. investigated corrected distance (CDVA) values, thickness...