A5057759062- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Retinal Imaging and Analysis
- Ophthalmology and Eye Disorders
- Ocular Surface and Contact Lens
- Coronary Interventions and Diagnostics
- Retinal and Macular Surgery
- Liver Disease Diagnosis and Treatment
- Optical Coherence Tomography Applications
- Cerebral Venous Sinus Thrombosis
- Pancreatitis Pathology and Treatment
- Vascular Procedures and Complications
- Corneal Surgery and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Acute Myocardial Infarction Research
- Ocular Infections and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurological Disorders and Treatments
- Retinopathy of Prematurity Studies
- Blood groups and transfusion
The University of Texas Health Science Center at Houston
2015-2024
University of Pittsburgh
1969-2024
Outcomes Research Consortium
2024
Emory University
2024
University of Houston
2024
University of Pittsburgh Medical Center
2023
John Wiley & Sons (United States)
2023
Robert Cizik Eye Clinic
2012-2022
Harris Health System
2021
Lyndon Baines Johnson Hospital
2021
The high rate of periprocedural complications resulting from atherothrombotic embolization after percutaneous intervention in diseased saphenous vein grafts is reduced by distal microcirculatory protection using a balloon occlusion and aspiration system. Whether filter-based catheters, which offer the inherent advantages maintained perfusion ease use, are as effective for this purpose has not been established.A total 651 patients undergoing 682 graft lesions were prospectively randomized to...
Background Early restoration and maintenance of normal (TIMI 3) blood flow during acute myocardial infarction is critical for optimal preservation left ventricular function survival. Recombinant plasminogen activator (r-PA, reteplase) a nonglycosylated deletion mutant wild-type tissue-type (TPA) that has been shown to achieve more rapid complete thrombolysis compared with other activators in animal models. Methods Results The RAPID Trial was designed test the hypothesis bolus administration...
Objective: To examine resource consumption and the direct costs of treating glaucoma at different disease severity levels.Design: Observational, retrospective cohort study based on medical record review.Participants: One hundred fifty-one records patients with primary open-angle or normal-tension glaucoma, suspect, ocular hypertension (age Ն18 years) were randomly selected from 12 sites in United States stratified according to International Classification Diseases, Ninth Revision, Clinical...
In 86,488 multiphasic examinations, mean leukocyte counts were highest in cigarette smokers, intermediate ex-cigarette and cigar or pipe lowest nonsmokers. Among the races, whites had highest, yellows next, blacks counts. The count was related to quantity smoked, inhalation, smoking duration. Most groups who changed habits showed corresponding changes Higher smokers appeared largely be a direct effect of smoking, although small part increase seemed attributable chronic bronchitis. A...
Fat distribution was assessed by a series of ten skinfold measurements in 7,717 persons voluntarily undergoing multiphasic health screening examination. From this total, 360 diabetic and 934 nondiabetic control subjects matched for race, sex, age, height, weight, fat patterns were compared direct measurements, triceps ratios subscapular ratios: thickness each the individual's skinfolds relative to his or respectively. Diabetic subjects, especially women, showed significant shift toward...
Background: Prolonged dual antiplatelet therapy (DAPT) after percutaneous coronary intervention is associated with increased bleeding, despite a reduced incidence of ischemic events. The SYNERGY everolimus-eluting stent thin-strut platinum-chromium that elutes everolimus from thin abluminal layer bioabsorbable polymer. These design elements may facilitate rapid endothelialization and enable shorter-duration DAPT. Methods: EVOLVE Short DAPT prospectively evaluated the safety 3-month in high...
Background —Inhibitors of the platelet glycoprotein IIb/IIIa receptor given intravenously have been shown to be effective in reducing ischemic complications after coronary angioplasty and unstable angina, making this a promising new class agents for treatment prevention events patients with acute syndromes. Sibrafiban (Ro 48–3657) is an oral, peptidomimetic, selective antagonist receptor. Methods Results —The Thrombolysis Myocardial Infarction (TIMI) 12 trial was phase II, double-blind,...
Sixty marrow transplant recipients with liver dysfunction underwent transvenous biopsy and measurement of the hepatic venous pressure gradient. Biopsies were done on 29 patients using a Cook needle inserted through jugular vein, 30 femoral vein Mansfield forceps, 1 patient both instruments. The average number evaluable portal spaces was 4.0 for aggregated specimens 5.2 forceps specimens. central venules 2.6 3.5 Tissue obtained had crush artifact, especially along edges, making assessment...
<h3>Objective</h3> To compare the efficacy and safety of a fixed combination 0.005% latanoprost 0.5% timolol maleate administered once daily vs monotherapy with either or twice daily. <h3>Methods</h3> Patients primary secondary open-angle glaucoma ocular hypertension participated in 6-month, randomized, double-masked, multicenter study 3 parallel treatment groups. The double-masked period was preceded by 2- to 4-week "run-in" timolol. Subjects could receive therapy during 6-month open-label...
Social class and racial differences in blood pressure. S L Syme, T W Oakes, G D Friedman, R Feldman, A B Siegelaub, M CollenCopyRight https://doi.org/10.2105/AJPH.64.6.619 Published Online: October 07, 2011
Normal rabbits immunized with bovine insulin in adjuvant produce circulating autoantibodies that bind large amounts of endogenous (measured by an immunoassay which distinguishes and exogenous insulin). In a series nine animals, two not only produced autoantibody but also, as result the autoimmune phenomenon, became acutely diabetic. Their blood sugar, antibody, bound to antibody morphologic lesions islets Langerhans observed light electron microscopy were compared those nondiabetic for...
To determine the safety and efficacy of a new-generation nitinol stent with enhanced flexibility in arterial lesions superficial femoral artery (SFA) proximal popliteal (PPA).The Complete Self-Expanding (SE) Multicenter Trial (ClinicalTrials.gov identifier NCT00814970) enrolled 196 patients (124 men; mean age 68.7±10.5 years) from 28 centers United States Europe. The presented intermittent claudication (193/196) or ischemic rest pain (3/196) were treated stents for obstructive SFA PPA. Over...
<h3>Importance</h3> Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations African ancestry compared European or Asian ancestry. Despite this, individuals remain understudied genomic research for blinding disorders. <h3>Objectives</h3> To perform genome-wide association study (GWAS) evaluate potential mechanisms pathogenesis loci associated primary glaucoma. <h3>Design, Settings, Participants</h3> A 2-stage GWAS discovery data...
PurposeTo compare the effectiveness and safety of MicroShunt (Santen Inc., Emeryville, CA, USA) versus trabeculectomy in patients with primary open-angle glaucoma (POAG).DesignProspective, randomized, multicenter trial conducted United States Europe.ParticipantsAdult (aged 40-85 years) mild to severe POAG inadequately controlled on maximum tolerated medical therapy intraocular pressure (IOP) ≥15 mmHg ≤40 mmHg.MethodsPatients were randomized 3:1 standalone implantation (n=395) or (n=132),...