Christian Loewe

ORCID: 0000-0003-2502-0676
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Advanced MRI Techniques and Applications
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Advanced X-ray and CT Imaging
  • Peripheral Artery Disease Management
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Valve Diseases and Treatments
  • Vascular Procedures and Complications
  • Cardiovascular Function and Risk Factors
  • Radiation Dose and Imaging
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Liver Disease Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Cardiac Structural Anomalies and Repair
  • Parathyroid Disorders and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Infectious Aortic and Vascular Conditions
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Renal and Vascular Pathologies
  • Radiology practices and education

Medical University of Vienna
2016-2025

University Medical Center Groningen
2024

British Heart Foundation
2024

University of Zurich
2024

Humanitas University
2024

Vienna General Hospital
2001-2023

Brunswick (United States)
2022

Albany Research Institute
2022

Providence College
2022

European Society of Radiology
2021

Because stent implantation for disease of the superficial femoral artery has been associated with high rates late clinical failure, percutaneous transluminal angioplasty is preferred endovascular treatment, and stenting recommended only in event suboptimal technical results. We evaluated whether primary a self-expanding nitinol (nickel-titanium) yielded anatomical benefits superior to those afforded by optional secondary stenting.We randomly assigned 104 patients who had severe claudication...

10.1056/nejmoa051303 article EN New England Journal of Medicine 2006-05-03

Primary stenting with self-expanding nitinol stents of the superficial femoral artery yielded improved morphological and clinical results compared balloon angioplasty optional until 12 months in a randomized controlled trial. We now report 2-year data on restenosis outcomes these patients.Of 104 patients chronic limb ischemia obstructions, 98 (94%) could be followed up 2 years after intervention for occurrence (>50%) by duplex ultrasound hemodynamic outcome treadmill walking distance ankle...

10.1161/circulationaha.107.688341 article EN Circulation 2007-05-15

10.1016/s0140-6736(18)32262-1 article EN The Lancet 2018-09-24

Transcatheter aortic valve replacement (TAVR) is a minimally invasive alternative to conventional in symptomatic patients with severe stenosis and contraindications surgery. The procedure has shown improve patient's quality of life prolong short- mid-term survival high-risk individuals, becoming widely accepted therapeutic option which been integrated into current clinical guidelines for the management valvular heart disease. Nevertheless, not every patient at surgery good candidate TAVR....

10.1007/s00330-019-06357-8 article EN cc-by European Radiology 2019-09-05

Tafamidis treatment positively affects left ventricular (LV) structure and function improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). We aimed to investigate the relationship between response cardiac burden identified by serial quantitative 99mTc-DPD SPECT/CT. furthermore identify nuclear imaging biomarkers that could be used quantify monitor tafamidis therapy.Forty wild-type ATTR-CM who underwent scintigraphy SPECT/CT at baseline after 61 mg once daily...

10.1093/ehjci/jead030 article EN cc-by European Heart Journal - Cardiovascular Imaging 2023-03-07

Recent randomized trials investigating stent implantation compared with balloon angioplasty for treatment of superficial femoral artery (SFA) disease have given divergent results in short (mean 5 cm) and intermediate 10 lesions. We reinvestigated whether primary nitinol stenting is associated a morphologic clinical benefit when percutaneous transluminal optional (PTA) intermediate-length lesions.We randomly assigned 73 patients severe claudication or chronic limb ischemia average 8 cm long...

10.1002/ccd.22128 article EN Catheterization and Cardiovascular Interventions 2009-05-07

PurposeTo test the hypothesis that simultaneous closure of at least 2 independent vascular territories supplying spinal cord and/or prolonged hypotension may be associated with symptomatic ischemia (SCI) after thoracic endovascular aortic repair (TEVAR). MethodsA pattern matching algorithm was used to develop a risk model for SCI using prospective 63-patient single-center cohort positive predictive value (PPV) intraoperative 4 (left subclavian, intercostal, lumbar, and hypogastric arteries)....

10.1583/11-3578.1 article EN Journal of Endovascular Therapy 2012-02-01

Abstract Aims Concomitant cardiac amyloidosis (CA) in severe aortic stenosis (AS) is difficult to recognize, since both conditions are associated with concentric left ventricular thickening. We aimed assess type, frequency, screening parameters, and prognostic implications of CA AS. Methods results A total 191 consecutive AS patients (81.2 ± 7.4 years; 50.3% female) scheduled for transcatheter valve replacement (TAVR) were prospectively enrolled. Overall, 81.7% underwent complete assessment...

10.1002/ejhf.1756 article EN cc-by-nc European Journal of Heart Failure 2020-02-20

Abstract Existing quantitative imaging biomarkers (QIBs) are associated with known biological tissue characteristics and follow a well-understood path of technical, clinical validation before incorporation into trials. In radiomics, novel data-driven processes extract numerous visually imperceptible statistical features from the data no priori assumptions on their correlation processes. The selection relevant (radiomic signature) trials therefore requires additional considerations to ensure...

10.1007/s00330-020-07598-8 article EN cc-by European Radiology 2021-01-25

Tafamidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). However, it is not yet known whether tafamidis affects cardiac deposition and structural changes the myocardium. We aimed to determine disease-modifying effects on myocardial progression identify imaging parameters that could be applied for specific therapy monitoring.ATTR-CM underwent serial magnetic resonance (CMR) using T1 mapping techniques derive extracellular volume (ECV). Patients receiving 61...

10.1093/ehjci/jeab226 article EN European Heart Journal - Cardiovascular Imaging 2021-10-27

Abstract Rationale To provide an overview of the current status cardiac multimodality imaging practices in Europe and radiologist involvement using data from European Society Cardiovascular Radiology (ESCR) MRCT-registry. Materials methods Numbers on CT MRI examinations were extracted MRCT-registry ESCR, entered between January 2011 October 2023 ( n = 432,265). Data collection included total/annual numbers examinations, indications, complications, reporting habits. Results Thirty-two...

10.1007/s00330-024-10644-4 article EN cc-by European Radiology 2024-02-28

Pregnancy has been reported to be an independent risk factor for 50% of acute aortic dissections recorded in women younger than 45 years age. The present epidemiologic study aimed identify whether this putative association pregnancy and type A dissection could artifact selective reporting.This population-based was conducted the City Vienna, Austria, Europe, average female population 34,1381 age range 15-45 who were followed up between 1994 2004 (total 3755.195 person-years observation)....

10.1016/j.ejcts.2010.12.070 article EN European Journal of Cardio-Thoracic Surgery 2011-02-27

The expression of chemokine receptor type 4 (CXCR4) was found co-localized with macrophages on the atherosclerotic vessel wall and participated in initial emigration leukocytes. Gallium-68 [68Ga]Pentixafor has recently been introduced for imaging atherosclerosis by targeting CXCR4. We sought to evaluate human lesions using PET/MRI.Thirty-eight oncology patients underwent PET/MR at baseline. Maximum standardized uptake values (SUVmax) were derived from hot seven arterial segments...

10.1007/s00259-017-3831-0 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2017-09-21

Sutureless and rapid-deployment valves were recently introduced into clinical practice. The Edwards INTUITY valve system is a combination of the Magna pericardial subvalvular stent-frame to enable rapid deployment. We performed parallel cohort study for comparison two types. All patients receiving either an Ease or due aortic stenosis from May 2010 until July 2014 included. Patients undergoing bypass surgery, additional procedure, atrial ablation surgery replacement ascending aorta excluded....

10.1093/icvts/ivw052 article EN Interactive Cardiovascular and Thoracic Surgery 2016-03-13
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