A5102833261- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Meningioma and schwannoma management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Adenosine and Purinergic Signaling
- interferon and immune responses
- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- Circular RNAs in diseases
- Chemokine receptors and signaling
- Cardiac Structural Anomalies and Repair
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Pulmonary Hypertension Research and Treatments
- Peripheral Artery Disease Management
- Vasculitis and related conditions
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac pacing and defibrillation studies
- Sarcoidosis and Beryllium Toxicity Research
Medical University of Vienna
2011-2024
Fachhochschule Wiener Neustadt
2024
Klinik und Poliklinik für Nuklearmedizin
1970-2020
University of Vienna
1970
The expression of chemokine receptor type 4 (CXCR4) was found co-localized with macrophages on the atherosclerotic vessel wall and participated in initial emigration leukocytes. Gallium-68 [68Ga]Pentixafor has recently been introduced for imaging atherosclerosis by targeting CXCR4. We sought to evaluate human lesions using PET/MRI.Thirty-eight oncology patients underwent PET/MR at baseline. Maximum standardized uptake values (SUVmax) were derived from hot seven arterial segments...
PET with (18)F-FDG has the potential to assess vascular macrophage metabolism. is most often used in combination contrast-enhanced CT localize increased metabolism specific arterial lesions. Novel PET/MRI hybrid imaging shows high for combined evaluation of atherosclerotic plaques, due superior morphological conspicuity plaque The purpose this study was evaluate reliability and accuracy uptake quantification compared PET/CT as a reference standard patients carotid plaques.The group comprised...
Objectives In cardiac amyloidosis (CA) protein misfolding and consecutive storage into the extracellular myocardial compartment causes left ventricular hypertrophy and, in later stages of disease, heart failure. The aim this study was to compare volume (ECV) measurements obtained from photon-counting CT (PCCT) imaging reference magnetic resonance (CMR) evaluate coronary artery disease (CAD) a CA cohort. Materials Methods Thirty patients (mean age 77.5 +/− 7.9 years) underwent clinically...
Summary Background The diagnosis of large vessel vasculitis (LVV) is often challenging due to the various clinical appearances and low prevalence. Hybrid imaging by positron emission tomography computed (PET/CT) a highly relevant modality for diagnostics disease surveillance but may be associated with significant amount radiation dose especially in patients complications. Objective aim this retrospective analysis was compare image quality impact hybrid methods PET/CT PET/MRI on potential...
Abstract Objective Epicardial adipose tissue (EAT) quantity is associated with poor cardiovascular outcomes. However, the quality of EAT may be incremental prognostic value. Cardiac magnetic resonance (CMR) gold standard for characterization but has never been applied assessment. We aimed to investigate measured on CMR T1 mapping as a predictor outcomes in an all‐comer cohort. Methods investigated association area and times (EAT‐T1) composite endpoint nonfatal myocardial infarction, heart...
Objective: To compare electrocardiographic (ECG)-triggered high-pitch (HP) dual-source CT angiography (CTA) with non-ECG-triggered HP CTA of the aorta, particularly ascending regard to image quality, motion artefacts, contrast-to-noise ratio (CNR), signal-to-noise (SNR) and radiation dose. Methods: 59 consecutive patients who had been referred for known or suspected aortic disease, previous intervention planned transapical transfemoral valve implantation were prospectively included. Patients...
Purpose To investigate whether elevated glucose metabolism in neurofibroma, determined by [F18]-FDG-PET, is correlated with cell density MRI, as expressed through the apparent diffusion coefficient. Materials and methods Patients diagnosed neurofibromatosis type 1 peripheral nerve sheath tumors (PNST) were enrolled this prospective, IRB-approved study. After a single [F18]-FDG injection, patients consecutively underwent [F18]-FDG-PET/CT [F18]-FDG-PET/MRI on same day. Maximum mean...
Positron emission tomography (PET) and magnetic resonance imaging (MRI) have both been used for decades in cardiovascular imaging. Since 2010, hybrid PET/MRI using sequential integrated scanner platforms has available, with cardiac PET/MR protocols increasingly incorporated into clinical workflows. Given the range of complementary information provided by each method, use may be justified beneficial particular settings evaluation different disease entities. In present joint position...
Abstract Background The pathophysiological hallmark of transthyretin amyloid cardiomyopathy (ATTR-CM) is the deposition within myocardium. However, association between myocardial load and quantitative cardiac 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) uptake barely investigated. Purpose We aimed to investigate relationship 99mTc-DPD load, assessed by extracellular volume (ECV) on magnetic resonance (CMR) imaging, along with function in patients ATTR-CM. Methods Forty...
Abstract Background Hepatic T1 times have been shown to predict adverse clinical outcomes. However, up date, the various causes contributing changes in hepatic are not fully understood. So far, strong correlations with liver congestion and fibrosis demonstrated. Valvular heart disease, especially tricuspid regurgitation (TR), can lead congestive hepatopathy (CH) might significantly increase values. In contrast, steatosis – commonly present patients cardiovascular disease - would result lower...
Abstract Background Neutrophil extracellular traps (NETs) are critical mediators of thromboinflammation during acute myocardial infarction (AMI). However, triggers and signalling pathways NETosis in AMI remain incompletely understood. Levels vesicles (EV) carrying oxidation-specific epitopes (OSE) originating from lipid peroxidation increased at the culprit site AMI. Importantly, natural IgM antibodies with specificity for OSE, such as malondialdehyde (MDA), have been shown to modulate...
Background: Through the development of robust techniques and their comprehensive validation, cardiac magnetic resonance imaging (CMR) has developed a wide range indications in its almost 25 years clinical use. The recording volumes systolic ventricular function as well characterization focal myocardial scars are now part standard CMR imaging. Recently, introduction accelerated image acquisition technologies, new methods T1 T2 mapping 4-D flow measurements, post-processing technique feature...
Poster: ECR 2011 / C-0365 Low-dose CT angiography of the supraaortic arteries: image quality and radiation exposure at 80kV tube voltage settings by: D. Beitzke1, F. Wolf1, G. Berzaczy1, R. Schernthaner1, Nolz1, C. Plank1, J. Lammer2, Loewe1; 1Vienna/AT, 2Wien/AT
Objectives.To investigate the association between global longitudinal strain (GLS) using feature tracking (FT) cardiovascular magnetic resonance imaging (CMR) and prognosis in patients with heart failure preserved ejection fraction (HFpEF). Background.Echocardiography-based studies have demonstrated that HFpEF left ventricular (LV) analyses can detect impaired systolic function despite might also predict outcome.CMR allows analysis FT is furthermore gold standard for assessment of volumes...