Malte Maria Sieren

ORCID: 0000-0002-3669-2892
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Research Areas
  • Aortic aneurysm repair treatments
  • Advanced X-ray and CT Imaging
  • Advanced MRI Techniques and Applications
  • Cardiac Imaging and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Radiation Dose and Imaging
  • Characterization and Applications of Magnetic Nanoparticles
  • Aortic Disease and Treatment Approaches
  • Peripheral Artery Disease Management
  • Surgical Simulation and Training
  • Radiomics and Machine Learning in Medical Imaging
  • Vascular Procedures and Complications
  • Minerals Flotation and Separation Techniques
  • Cardiovascular Function and Risk Factors
  • Geomagnetism and Paleomagnetism Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Coronary Interventions and Diagnostics
  • COVID-19 diagnosis using AI
  • Asthma and respiratory diseases
  • Photoacoustic and Ultrasonic Imaging
  • Anatomy and Medical Technology
  • Cerebrovascular and Carotid Artery Diseases
  • COVID-19 Clinical Research Studies
  • Lung Cancer Diagnosis and Treatment
  • Renal and Vascular Pathologies

University of Lübeck
2016-2025

University Hospital Schleswig-Holstein
2016-2025

Klinik und Poliklinik für Nuklearmedizin
2017-2025

Universitäres Kinderwunschzentrum Lübeck
2020-2025

Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering
2025

Institute for Integrative and Experimental Genomics
2024

Maine Farmland Trust
2024

Homerton University Hospital
2017

Johannes Gutenberg University Mainz
2007-2009

Abstract Rationale To provide an overview of the current status cardiac multimodality imaging practices in Europe and radiologist involvement using data from European Society Cardiovascular Radiology (ESCR) MRCT-registry. Materials methods Numbers on CT MRI examinations were extracted MRCT-registry ESCR, entered between January 2011 October 2023 ( n = 432,265). Data collection included total/annual numbers examinations, indications, complications, reporting habits. Results Thirty-two...

10.1007/s00330-024-10644-4 article EN cc-by European Radiology 2024-02-28

Different software programs are available for the evaluation of 4D Flow cardiovascular magnetic resonance (CMR). A good agreement results between is a prerequisite acceptance method. Therefore, goal was to compare quantitative from cross-over comparison in individuals examined on two scanners different vendors analyzed with four postprocessing packages. Eight healthy subjects (27 ± 3 years, women) were each 3T CMR systems (Ingenia, Philips Healthcare; MAGNETOM Skyra, Siemens Healthineers)...

10.1186/s12968-023-00921-4 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2023-02-01

Abstract Objectives To evaluate work expectations of radiologists at different career levels, their fulfillment, prevalence exhaustion, and exhaustion-associated factors. Methods A standardized digital questionnaire was distributed internationally to all levels in the hospital ambulatory care via radiological societies sent manually 4500 largest German hospitals between December 2020 April 2021. Statistics were based on age- gender-adjusted regression analyses respondents working Germany...

10.1007/s00330-023-09510-6 article EN cc-by European Radiology 2023-03-10

Diagnosing myocarditis relies on multimodal data, including cardiovascular magnetic resonance (CMR), clinical symptoms, and blood values. The correct interpretation integration of CMR findings require radiological expertise knowledge. We aimed to investigate the performance Generative Pre-trained Transformer 4 (GPT-4), a large language model, for report-based medical decision-making in context cardiac MRI suspected myocarditis.

10.1016/j.jocmr.2024.101068 article EN cc-by Journal of Cardiovascular Magnetic Resonance 2024-01-01

Mast cells are thought to contribute allergic airway disease. However, the role of mast cell-produced mediators, such as tumour necrosis factor (TNF), for development disease is unclear. In order define in acute two strains cell-deficient mice (Kit W/Wv and Kit W-sh/W-sh ) were studied. Compared with their wild-type littermates, developed significantly lower responsiveness methacholine less inflammation goblet cell metaplasia, following sensitisation absence adjuvant challenge. Transfer bone...

10.1183/09031936.00058907 article EN European Respiratory Journal 2007-12-19

Magnetic particle imaging (MPI) is a promising modality nearing clinical introduction. MPI's tracer-based principle allows for highly sensitive background-free imaging. Potential applications include cardiovascular and endovascular interventions. In principle, medical instruments are invisible in MPI due to the missing signal generation. Therefore, permanent marking technologies have been introduced. Additionally, temporary markers of interest follow-up examinations after stent implantation...

10.1002/mabi.202400495 article EN cc-by Macromolecular Bioscience 2025-02-06

Background/Objectives: In the burgeoning field of medical imaging and Artificial Intelligence (AI), high-quality annotations for training AI-models are crucial. However, there still only a few large datasets, as segmentation is time-consuming, experts have limited time. This study investigates how experience radiologists affects quality annotations. Methods: We randomly collected 53 anonymized chest radiographs. Fifteen readers with varying levels expertise annotated anatomical structures...

10.3390/diagnostics15060777 article EN cc-by Diagnostics 2025-03-19

10.1055/s-0045-1802941 article DE RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2025-03-01

Purpose 4D and 2D phase-contrast MRI (2D Flow MRI, respectively) are increasingly being used to noninvasively assess pulmonary hypertension (PH). The goals of this study were i) evaluate whether established quantitative parameters in associated with can be assessed using MRI; ii) compare results from on a digital broadband 3T MR system data clinically MRI-techniques as well conservation mass analysis phantom correction iii) elaborate the added value secondary flow patterns detecting PH....

10.1371/journal.pone.0224121 article EN cc-by PLoS ONE 2019-10-24

Abstract Purpose To assess the technical feasibility, safety, and clinical success rate of trans-arterial embolization (TAE) as an emergency treatment for acute lower gastrointestinal bleeding (LGIB). Materials methods Consecutive patients who received urgent TAE due to active LGIB at five academic centers in Germany were retrospectively analyzed. was confirmed localized using contrast-enhanced computed tomography (CT) or endoscopy. Outcome parameters including rates well ischemia-related...

10.1007/s00330-024-11102-x article EN cc-by European Radiology 2024-10-16

Abstract Purpose During endovascular aneurysm repair (EVAR) procedures, medical instruments are guided with two-dimensional (2D) fluoroscopy and conventional digital subtraction angiography. However, this requires X-ray exposure contrast agent is used, the depth information missing. To overcome these drawbacks, a three-dimensional (3D) guidance approach based on tracking systems introduced evaluated. Methods A multicore fiber Bragg gratings for shape sensing three electromagnetic (EM)...

10.1007/s11548-020-02167-2 article EN cc-by International Journal of Computer Assisted Radiology and Surgery 2020-05-07

Medical ultrasound (US) is a commonly used modality for image-guided procedures. Recent research systems providing an in situ visualization of 2D US images via augmented reality (AR) head-mounted display (HMD) were shown to be advantageous over conventional imaging through reduced task completion times and improved accuracy. In this work, we continue the direction recent developments by describing first AR HMD application visualizing real-time volumetric (3D) guiding vascular punctures. We...

10.3390/s23042168 article EN cc-by Sensors 2023-02-15

Purpose: Magnetic particle imaging (MPI) is an emerging medical modality that on the verge of clinical use. In recent years, cardiovascular applications have shown huge potential like, e.g., intraprocedural guidance stent placement through MPI. Due to lack signal generation, nano-modifications been necessary visualize commercial instruments until now. this work, it investigated if interventional devices can be tracked with MPI without any nano-modification. Material and Methods: Potential...

10.2147/ijn.s447823 article EN cc-by-nc International Journal of Nanomedicine 2024-03-01

The assessment of lymph node metastases is critical for accurate cancer staging and consequently the decision treatment options. Lymph a challenging, time-consuming task due to fact that nodes have ill-defined borders as well varying sizes morphological characteristics. purpose this study evaluate effects using different anatomical priors with aim guiding network attention within application segmentation pathological in mediastinum. first presented prior, distance map, displays commonly...

10.1117/12.3006158 article EN Medical Imaging 2018: Computer-Aided Diagnosis 2024-04-02

Currently, uoroscopy and conventional digital subtraction angiography are used for imaging guidance in endovascular aortic repair (EVAR) procedures. Drawbacks of these image modalities X-ray exposure, the usage contrast agents lack depth information. To overcome disadvantages, a catheter prototype containing multicore fiber with Bragg gratings shape sensing three electromagnetic (EM) sensors locating was built this study. Furthermore, model processing input data from tracking systems to...

10.1117/12.2548094 article EN 2020-03-16
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