- Characterization and Applications of Magnetic Nanoparticles
- Geomagnetism and Paleomagnetism Studies
- Minerals Flotation and Separation Techniques
- Advanced X-ray and CT Imaging
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Advanced MRI Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- Electrical and Bioimpedance Tomography
- Asthma and respiratory diseases
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Vascular Procedures and Complications
- Allergic Rhinitis and Sensitization
- Fluid dynamics and aerodynamics studies
- Moyamoya disease diagnosis and treatment
- Radiomics and Machine Learning in Medical Imaging
- Spacecraft Dynamics and Control
- Nanoparticle-Based Drug Delivery
- Cerebrovascular and genetic disorders
- MRI in cancer diagnosis
- COVID-19 Clinical Research Studies
- Inflammatory Myopathies and Dermatomyositis
- Magnetic properties of thin films
University Hospital Schleswig-Holstein
2018-2025
University of Lübeck
2018-2025
Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering
2025
Universitäres Kinderwunschzentrum Lübeck
2020-2025
Institute for Integrative and Experimental Genomics
2024
Klinik und Poliklinik für Nuklearmedizin
2018-2022
Kerckhoff Klinik
2016-2018
Justus-Liebig-Universität Gießen
2016-2018
Heidelberg University
2002-2016
Heinrich Heine University Düsseldorf
1981-1983
Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or neurosurgical clipping intervention. Here, we propose helically shaped magnetic micro-robot, which can be steered fields in an untethered manner could applied for novel procedure. This is shown navigating the micro-robot through additively manufactured phantom of human cerebral aneurysm. The with particle imaging (MPI) scanner, allows navigation tomographic visualization same machine....
Different software programs are available for the evaluation of 4D Flow cardiovascular magnetic resonance (CMR). A good agreement results between is a prerequisite acceptance method. Therefore, goal was to compare quantitative from cross-over comparison in individuals examined on two scanners different vendors analyzed with four postprocessing packages. Eight healthy subjects (27 ± 3 years, women) were each 3T CMR systems (Ingenia, Philips Healthcare; MAGNETOM Skyra, Siemens Healthineers)...
Magnetic particle imaging (MPI) is a promising modality nearing clinical introduction. MPI's tracer-based principle allows for highly sensitive background-free imaging. Potential applications include cardiovascular and endovascular interventions. In principle, medical instruments are invisible in MPI due to the missing signal generation. Therefore, permanent marking technologies have been introduced. Additionally, temporary markers of interest follow-up examinations after stent implantation...
Background/Objectives: In the burgeoning field of medical imaging and Artificial Intelligence (AI), high-quality annotations for training AI-models are crucial. However, there still only a few large datasets, as segmentation is time-consuming, experts have limited time. This study investigates how experience radiologists affects quality annotations. Methods: We randomly collected 53 anonymized chest radiographs. Fifteen readers with varying levels expertise annotated anatomical structures...
Viral genesis is the most common cause of myocarditis. COVID-19-associated myocarditis seems to be a notable extrapulmonary manifestation, which may result in need for different treatment. There has been no positive polymerase chain reaction (PCR) testing SARS-CoV-2 heart specimens, thus far.A 48-year-old male patient presented with fever, dyspnoea, and haemoptysis. Laboratory findings showed highly elevated inflammatory cardiac damage markers. Thoracic computed tomography (CT) revealed...
Vascular interventions are a promising application of Magnetic Particle Imaging enabling high spatial and temporal resolution without using ionizing radiation. The possibility to visualize the vessels as well devices, especially at same time multi-contrast approaches, enables higher accuracy for diagnosis treatment vascular diseases. Different techniques make devices MPI visible have been introduced so far, such varnish markings or filling balloons. However, all approaches include challenges...
Purpose: Magnetic particle imaging (MPI) is an emerging medical modality that on the verge of clinical use. In recent years, cardiovascular applications have shown huge potential like, e.g., intraprocedural guidance stent placement through MPI. Due to lack signal generation, nano-modifications been necessary visualize commercial instruments until now. this work, it investigated if interventional devices can be tracked with MPI without any nano-modification. Material and Methods: Potential...
A long cylindrical body of circular cross‐section and homogeneous density may float in all orientations around the cylinder axis. It is shown that there are also bodies non‐circular cross‐sections which any direction. Apart from those found by Auerbach for ρ= 1/2 , one‐parameter families ρ≠ have a p ‐fold rotation symmetry. For given they this property − 2 different densities ρ. The differential equation governing boundary curve derived. Its solution expressed terms an elliptic integral.
Explicit solutions of the two-dimensional floating body problem (bodies that can float in all positions) for relative density different from 1/2 and tire track (tire tracks a bicycle, which do not allow to determine, way bicycle went) are given, differ circles. Starting point is differential equation given by author archive physics/0205059 Studies Appl. Math. 111 (2003) 167-183. The curves also trajectories charges perpendicular magnetic field.
Endovascular stents are medical devices, which implanted in stenosed blood vessels to ensure sufficient flow. Due a high rate of in-stent re-stenoses, there is the need noninvasive imaging method for early detection stent occlusion. The evaluation lumen with computed tomography (CT) and magnetic resonance (MRI) limited by material-induced artifacts. purpose this work investigate potential tracer-based modality particle (MPI) visualization quantification.In vitro study, 21 endovascular were...
Anatomically pre-shaped sinus prostheses (SP) were developed to mimic the aortic with goal preserve near physiological hemodynamic conditions after valve-sparing root replacement. Although SP have shown more flow patterns, a comparison straight tube prosthesis and analysis of derived quantitative parameters is lacking. Hence, this study sought analyze differences in wall shear stress (WSS) between anatomically SP, conventional (TP), age-matched healthy subjects) using time-resolved...