A5034288024- Characterization and Applications of Magnetic Nanoparticles
- Geomagnetism and Paleomagnetism Studies
- Microfluidic and Bio-sensing Technologies
- Electrical and Bioimpedance Tomography
- Magnetic properties of thin films
- Minerals Flotation and Separation Techniques
- Advanced Numerical Analysis Techniques
- Tribology and Lubrication Engineering
- Numerical methods in engineering
- Surface Roughness and Optical Measurements
- Advanced MRI Techniques and Applications
- Polynomial and algebraic computation
- Geophysical and Geoelectrical Methods
- Fractional Differential Equations Solutions
- Non-Destructive Testing Techniques
- Nuclear Physics and Applications
- Magneto-Optical Properties and Applications
- Advanced Neuroimaging Techniques and Applications
- Nanoparticle-Based Drug Delivery
- Advanced X-ray Imaging Techniques
- Soil Moisture and Remote Sensing
Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering
2022-2025
University of Lübeck
2014-2022
Magnetic Particle Imaging is a new medical imaging modality, which detects superparamagnetic iron oxide nanoparticles. The particles are excited by magnetic fields. Most scanners have tube-like measurement field and therefore, both the of view object size limited. A single-sided scanner has advantage that not limited in size, only penetration depth prototype for 1D been presented 2009. Simulations published 2D first measurements carried out. In this paper, calibration-based reconstruction...
Magnetic particle imaging (MPI) is a promising modality nearing clinical introduction. MPI's tracer-based principle allows for highly sensitive background-free imaging. Potential applications include cardiovascular and endovascular interventions. In principle, medical instruments are invisible in MPI due to the missing signal generation. Therefore, permanent marking technologies have been introduced. Additionally, temporary markers of interest follow-up examinations after stent implantation...
Magnetic Particle Imaging (MPI) is a multidisciplinary research field. It has many promising applications, and the imaging devices are actively being scaled to human size. As such this work aims at providing insight into some of different fields connected by MPI. The areas covered within include, amongst other things, simulations magnetic particles, particle spectroscopy, MPI scanners future theranostic applications. A short introduction in each field given followed discussion recent trends...
Magnetic Particle Imaging (MPI) is an emerging technology in the field of (pre)clinical imaging. The acquisition a particle signal realized along specific sampling trajectories covering defined view (FOV). In system matrix (SM) based reconstruction procedure, commonly used path MPI Lissajous trajectory. Such trajectory features inhomogeneous coverage FOV, i.e. center region sampled less dense than regions towards edges FOV. Conventionally, respective SM and subsequent do not reflect this...
The imaging technology magnetic particle allows the detection of material, in particular superparamagnetic nanoparticles, by remagnetization material via fields. application is aimed at medical where particles are applied as tracer directly into blood stream. Medical safety considerations such peripheral nerve stimulation limit maximal amplitude fields and turn field view size. To handle this constraint concept patches was introduced, which a shift to different positions order enlarge area....
Vascular interventions are a promising application of Magnetic Particle Imaging enabling high spatial and temporal resolution without using ionizing radiation. The possibility to visualize the vessels as well devices, especially at same time multi-contrast approaches, enables higher accuracy for diagnosis treatment vascular diseases. Different techniques make devices MPI visible have been introduced so far, such varnish markings or filling balloons. However, all approaches include challenges...
Magnetic particle imaging (MPI) is a new medical technique visualizing the concentration distribution of superparamagnetic nanoparticles used as tracer material. MPI not yet in clinical routine, since one challenges upscaling scanners. Typically, magnetic fields scanners are generated electromagnetically, resulting an immense power consumption but providing high flexibility terms adjusting field strengths and very fast image acquisition rates. Permanent magnets provide flux densities do need...
Magnetic Particle Imaging (MPI) is a tomographic imaging modality capable to visualize tracers using magnetic fields. A high gradient strength mandatory, achieve reasonable image quality. Therefore, power optimization of the coil configuration essential. In order realize multi-dimensional efficient field generator, following improvements compared conventionally used Maxwell configurations are proposed: (i) curved rectangular coils, (ii) interleaved and (iii) multi-layered coils. Combining...
Magnetic particle imaging (MPI) is a promising new in-vivo medical modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response an applied magnetic field. In this paper we provide mathematical analysis the modeled MPI operator univariate situation. We Hilbert space setup, decomposed into simple building blocks and these analyzed with respect to properties. turn, obtain forward and, particular, its ill-posedness further get that singular values core...
The reconstruction of a particle concentration in magnetic imaging is commonly based on using system matrix, whose acquisition time consuming and storing challenging. It has been shown recently that the can be reduced with methods compressed sensing storage requirements by sparse representation. To improve reconstruction, signals low signal-to-noise ratio (SNR) are discarded. determination SNR difficult for undersampled signals. In this paper, mixing order acquired harmonics calculated to...
The magnetic particle imaging (MPI) technology is a new technique featuring an excellent possibility to detect iron oxide based nanoparticle accumulations in vivo. excitation of the particles and turn signal generation MPI are achieved by using oscillating fields. In order realize spatial encoding, field-free point (FFP) steered through field view (FOV). Such positioning FFP can thereby be mechanical or electromagnetical movement. Conventionally, data acquisition path either planar 2-D 3-D...
Magnetic particle imaging is an modality that acquires quantitative information about the spatial distribution of magnetic nanoparticles. In combination with excellent and temporal resolution due to fact no harmful radiation used, technique offers possibilities respect medical application. As such, interventional scenarios, where it mandatory visualize used instruments, are a perfectly suitable area This paper describes results feasibility study novel single-sided coil arrangement based on...
In this paper, we study the compression of magnetic particle imaging system matrix for setups in which a field free point is moved along a Lissajous trajectory. We show that large number zeros simulated transformed obtained when orthogonal transforms applied to spatial domain have only symmetric and antisymmetric basis functions. For measured matrices, property holds approximately, because noise induced by scanner hardware. The required symmetry properties are naturally fulfilled by some...
Abstract Purpose To evaluate heating of a redilatable stent for the treatment aortic coarctation in neonates and small children new imaging modality magnetic particle established resonance imaging. Materials Methods The cobalt-chromium (BabyStent, OSYPKA AG, Rheinfelden, Germany) has design which allows redilatation adjustment diameter from 6 to 16 mm use coarctation. loses its radial integrity while opening at predetermined breaking points 14 or mm, respectively. We measured temperature...
Magnetic particle imaging (MPI) is a tomographic method to determine the spatio-temporal distribution of magnetic nanoparticles. In this document, file format for standardized storage MPI and spectroscopy (MPS) data introduced. The aim Particle Imaging Data Format (MDF) provide coherent way exchanging MPS acquired with different devices worldwide. focus MDF on sequence parameters, measurement data, calibration reconstruction data. based hierarchical document in version 5 (HDF5). This...
Magnetic particle imaging (MPI) is an technique based on the determination of magnetic material by moving a field-free point along specified trajectories, which are used to sample field view. Due technical and safety reasons, view limited in size. To enlarge size view, trajectory patches used, sampled separately combined consecutively entire The aim this paper analyze effect different trajectories with patch approach. In addition, empiric study performed influence overlapped each cutoff as...
In this paper, we study the efficiency of five different field free point trajectories in two-dimensional magnetic particle imaging for compressed-sensing based reconstruction partially measured system matrices. To show suitability trajectories, with identical repetition times were simulated using on same scanner setup. We that all approach matrix is possible and promising real-world scenarios. Also validate already known fact Lissajous trajectory appropriate compressed sensing approach....
Abstract Magnetic Particle Imaging (MPI) is a new imaging technique with an outstanding sensitivity, high temporal and spatial resolution. MPI based on the excitation detection of magnetic tracer material by using fields. The resolution strongly depends reconstruction parameters selection weighting system function frequency components. Currently, no fundamental strategy to weight for given. In this contribution, influence different methods analyzed. Thereby, proposed select components...