A5015942063- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Venous Thromboembolism Diagnosis and Management
- Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Gastrointestinal disorders and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pleural and Pulmonary Diseases
- Bone health and treatments
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Voice and Speech Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bladder and Urothelial Cancer Treatments
- Pneumothorax, Barotrauma, Emphysema
- MRI in cancer diagnosis
- Multiple Myeloma Research and Treatments
- Biliary and Gastrointestinal Fistulas
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Cardiac tumors and thrombi
- Hematological disorders and diagnostics
University of Lübeck
2019-2025
University Hospital Schleswig-Holstein
2019-2025
Universitäres Kinderwunschzentrum Lübeck
2020-2025
University Medical Center
2023
University Hospital and Clinics
2023
Klinik und Poliklinik für Nuklearmedizin
2019-2022
Abstract Background Pulmonary arterial embolism (PE) is not well characterized in elderly patients. In addition, unnecessary computed tomography pulmonary angiography (CTPA) examinations are often performed within this patient group, especially if the pretest probability low. Objective To identify differences clinical presentation patients aged ≥80 years compared to <80 and effect of a BGA-optimized reduce CTPAs according age category. Materials methods A retrospective analysis with...
Background: The introduction of checkpoint inhibitors is a long-awaited new option for urothelial cancer with poor prognosis. Apart from clinical studies, the data on real world experience scarce. Methods: Patients monotherapy either Atezolizumab, Nivolumab or Pembrolizumab after chemotherapy were included. Adverse events and immune related adverse as well survival imaging analyses recorded in prospectively designed multi-center base. Duration response, progression free (PFS), overall (OS)...
Abstract Background The composition of the tumor microenvironment (TME) is conditioned by immunity and inflammatory response. Nutritional inflammation-based risk scores have emerged as relevant predictors survival outcome across a variety hematological malignancies. Methods In this retrospective multicenter trial, we ascertained prognostic impact established nutritional [Glasgow Prognostic Score (GPS), C-reactive–protein/albumin ratio (CAR), neutrophil–lymphocyte (NLR), index (PNI), (PI)] in...
Abstract In patients with suspected pulmonary embolism (PE), the number of unnecessary computed tomography angiography (CTPA) scans remains high, especially in low pre-test probability (PTP). So far, no study showed any additional benefit capillary blood gas analysis (BGA) diagnostic algorithms for PE. this retrospective PE and subsequent CTPA, clinical data, D-dimer levels BGA parameters (including standardized PaO2) were analyzed. Logistic regression analyses performed to identify...
Abstract Purpose Iodine-containing contrast agent (CA) used in contrast-enhanced CT angiography (CTA) can pose a health risk for patients. A system that adjusts the frequently standard CA dose individual patients based on their clinical parameters be useful. As basis quality of image CTA volumes has to determined, especially recognize excessive induced by overdosing. However, manual assessment with ROI-based classification is time-consuming step everyday practice. Methods We propose method...
Abstract Objectives In this paper, an artificial intelligence-based algorithm for predicting the optimal contrast medium dose computed tomography (CT) angiography of aorta is presented and evaluated in a clinical study. The prediction reduction modelled as classification problem using image main feature. Methods This performed by random decision forests (RDF) k-nearest-neighbor methods (KNN). For selection parameter subsets all possible combinations 22 parameters (age, blood pressure, etc.)...
Iodine-containing contrast agents (CA) are important for enhanced image in CT imaging especially angiography (CTA). CA however poses a risk to the patient since it can e.g. harm kidneys. In clinical routine often standard dose is applied that does not take differences between individual patients into account. We propose method as preliminary stage determines excessive and overdosing by assessing CTA images obtained with ulrich medical motion media injector RIS/PACS interface. A resulting...
Bei der aktuell 62-jährigen Patientin war 1992 ein invasiv-duktales, multifokales Mammakarzinom diagnostiziert worden. Nach Ablatio mammae rechts mit Axilladissektion und anschließender Radiatio rechten Brustwand sowie parasternalen infraklavikulären Lymphknotenstationen waren mehrfach lokoregionäre Rezidive aufgetreten, die lokal reseziert teilweise nachbestrahlt wurden. 5 Jahre vor aktuellen Vorstellung 2 Rippen rechtsseitig eine Defektdeckung einem gestielten Latissimus-dorsi-Lappen...
This work aims to recognize the patient individual possibility of contrast dose reduction in CT angiography. system should help identify whether agent angiography can be reduced avoid side effects. In a clinical study, 263 angiographies were performed and, addition, 21 parameters recorded for each before administration. The resulting images labeled according their quality. It is assumed that could with excessive contrast. These data was used develop model predicting based on using logistic...
Die Bewertung von Biomarkern in der Medizin ist eine Stärke Radiologie und Ziel des Radiomics-Projekts. Computertomografie eignet sich gut zur wie Muskelmasse (CSMA), die z.B. bei Vorhersage Krankheitsmortalität -morbidität verwendet werden. Daher war es das dieser Studie, neuartige halbautomatische Software zeiteffizienten CSMA-Quantifizierung zu evaluieren.
Die Sarkopenie kann als wichtiger prognostischer Marker maligner Erkrankungen auf Basis der cross-sectional muscle area (CSMA) mittels Computertomografie (CT) zuverlässig bestimmt werden. Aktuelle Studien zeigen, dass neben bereits validierten CSMA-Beurteilung Höhe des dritten Lendenwirbels eine Quantifizierung M. pectoralis-Querschnitts vierten Brustwirbels zu einer verbesserten Aussage führt. Ziel war es daher, neue Software Ihre Anwendung zur semiautomatischen Pectoralis-CSMA überprüfen.
Zielsetzung Standardprotokolle oder gewichtsadaptierte Injektionsprotokolle werden bei der Kontrastmittelgabe im Rahmen von CT Angiografien (CTA) hohen Variabilität patientenspezifischen Einflussgrößen nicht ausreichend gerecht. In unserer Studie sollen nichtinvasiv und einfach messbare Parameter identifiziert werden, aus denen mit Hilfe künstlicher Intelligenz patientenindividuelle abgeleitet können.
Einleitung Die häufigste Ursache eines mechanischen Dickdarmileus ist das kolorektale Karzinom, gefolgt von chronischer Divertikulitis, Adhäsionen und Volvulus [1]. Betroffen sind vor allem ältere Patienten. typische Klinik umfasst ein geblähtes Abdomen, abdominelle Schmerzen sowie Stuhl- Windverhalt. Wir präsentieren einen Fall mit einer seltenen Dickdarmileus.