- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Air Quality and Health Impacts
- Atmospheric chemistry and aerosols
- Pharmaceutical and Antibiotic Environmental Impacts
- Heavy Metal Exposure and Toxicity
- Per- and polyfluoroalkyl substances research
- Recycling and Waste Management Techniques
- Carcinogens and Genotoxicity Assessment
- Aeolian processes and effects
- Pesticide Residue Analysis and Safety
- Infection Control and Ventilation
- Thallium and Germanium Studies
- Retinoids in leukemia and cellular processes
- Female Genital Mutilation/Cutting Issues
- Arsenic contamination and mitigation
- Computational Drug Discovery Methods
- Agriculture Sustainability and Environmental Impact
- Pregnancy and Medication Impact
- Medical History and Research
- SARS-CoV-2 and COVID-19 Research
- Selenium in Biological Systems
- Trace Elements in Health
- SARS-CoV-2 detection and testing
Zhejiang University
2022-2025
Research Center for Eco-Environmental Sciences
2021-2025
Chinese Academy of Sciences
2021-2025
Beijing Normal University
2016-2021
Human uptake abundance of microplastics via various pathways, and they accumulate in human liver, kidney, gut even placenta (especially with a diameter 1 μm or less). Recent scientific studies have found that exposure to causes intestinal inflammation liver metabolic disorder, but it remains largely unknown whether the damage may cause further development severe diseases. In this study, we discovered one such potential diseases be induced by small-sized (with μm) performing multi-organ...
We have been effectively protected by disposable propylene face masks during the COVID-19 pandemic; however, they may pose health risks due to release of fine particles and chemicals. measured micro/nanoparticles organic chemicals in medical masks, surgical (K)N95 respirators. In breathing-simulation experiment, no notable differences were found total number among mask types or between breathing intensities. However, when considering subranges, <2.5 μm accounted for ∼90% micro/nanoparticles....
The global practice of reusing sewage sludge in agriculture and its landfill disposal reintroduces environmental contaminants, posing risks to human ecological health. This study screened from 30 Chinese cities for androgen receptor (AR) disruptors, utilizing a disruptor list the Toxicology 21st Century program (Tox21), identified 25 agonists 33 antagonists across diverse use categories. Predominantly, natural products 5α-dihydrotestosterone thymidine emerged as agonists, whereas industrial...
ADVERTISEMENT RETURN TO ISSUEViewpointNEXTResurgence of Sandstorms Complicates China's Air Pollution SituationGang LiGang LiState Key Laboratory Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy Beijing 100085, ChinaMore by Gang Li, Dawei LuDawei LuState Lu, Xiaoxi YangXiaoxi YangState Yang, Haiyan ZhangHaiyan ZhangSchool Environment, Hangzhou Institute Advanced Study, University 310024, Zhang, Yunhe GuoYunhe GuoState Guo, Guangbo...
Groundwater can be contaminated by PFAS emissions, yet research on the presence and associated risks of in groundwater underlying different land-use areas remains limited. Herein, high-resolution mass spectrometry-based suspect nontarget analyses were performed to determine occurrence samples obtained from a rural area, planting region, vicinities pharmaceutical park, an airport, industrial park Datong City, China. A total 31 (16 emerging 15 legacy PFAS) identified, ΣPFAS concentrations...
Despite extensive poly/perfluoroalkyl substance (PFAS) discovery studies in various samples, the exposure spectrum fluorochemical occupational workers remains largely unexplored. Here, serum samples from 28 at a facility were analyzed using nontarget techniques, identifying 64 PFAS classes, including 15 novel ones such as pentafluorosulfur ether-substituted perfluoroalkyl sulfonic acids, hydrogen-substituted perfluoroalkylamines, and perfluoroalkylsulfonyl protocatechualdehyde esters....
Despite the fact that coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome 2 (SARS-CoV-2), has been disrupting human life and health worldwide since outbreak in late 2019, impact of exogenous substance exposure on viral infection remains unclear. It is well-known that, during infection, organism receptors play a significant role mediating entry viruses to enter host cells. A major receptor SARS-CoV-2 angiotensin-converting enzyme (ACE2). This study proposes deep...
Although rubber shoes have been extensively produced and used for the past century, chemical additives released from shoe soles, as well aquatic ecological risks, overlooked. Using nontargeted analysis, this study detected 106 70 chemicals in soles leachates, respectively. The total concentrations were range of 203 to 3.21 × 103 μg/g 247 5.32 104 μg/L leachates. distributed 10 groups, among which phthalate esters dominant additives. Chemical compositions varied significantly different shoes,...
Exposure to organochlorine pesticides (OCPs) can cause adverse health effects in the female population. We investigated dietary OCP intake of childbearing-age women living large agricultural areas Northern China, as well their associated risks. Ten were recruited during 2015–2016. Their weekly diaries and food samples collected over course five visits. The residues 322 from seven categories (i.e., cereal, vegetable, fruit, fish, meat, egg, milk) analyzed by gas chromatography-mass...
Knowledge of the biotransformation tetrabromobisphenol A (TBBPA) and its related contaminants by human gut microbiota (GM) remains unexplored. Here, TBBPA four analogs were incubated with mixed GM strains, nine rhamnosylated or debrominated transformation products (TPs) discovered. Remarkably, rhamnosylation was identified as a common unique microbial pathway for these contaminants, six seven TPs reported first time. Additionally, kinetic study also showed rapid strong bioaccumulation
Exposure to electronic and electrical waste (e-waste) has been related a few adverse health effects. In this study, sediment samples from an e-waste recycling town in China were collected, aryl hydrocarbon receptor (AhR) agonists the identified using effect-directed analysis (EDA) strategy. The CBG2.8D cell line reporter gene bioassay was used as toxicity test, while suspect screening against chemical databases performed for potential AhR agonist identification where both gas chromatography-...
The problem of food-mediated transregional delivery polybrominated diphenyl ethers (PBDEs) in China is widespread but seriously ignored. Meanwhile, the risk assessment exposure to dietary pollutants for regional populations based on bioaccessibility considered better reflect real exposure. Herein, we drew a spectrum eight PBDEs and 43 typical foods obtained from Beijing using three-stage vitro digestion simulation method. Further, Monte Carlo was used simulate impact PBDE residents, studied...
The problem of food-mediated transregional delivery polybrominated diphenyl ethers (PBDEs) in China is widespread but seriously ignored. Meanwhile, the risk assessment exposure to dietary pollutants for regional populations based on bioaccessibility considered better reflect real exposure. Herein, we drew a spectrum eight PBDEs and 43 typical foods obtained from Beijing using three-stage vitro digestion simulation method. Further, Monte Carlo was used simulate impact PBDE residents, studied...