A simple, high-yielding synthesis of 2,4,5-trisubstituted imidazoles from 1,2-diketones and aldehydes in the presence NH4OAc is described. Under microwave irradiation, alkyl-, aryl-, heteroaryl-substituted are formed yields ranging 80 to 99%. Short syntheses lepidiline B trifenagrel illustrate utility this approach.

Abstract Circularly polarized organic light‐emitting diodes (CP‐OLEDs) are particularly favorable for the direct generation of CP light, and they demonstrate a promising application in 3D display. However, up to now, such devices have suffered from low brightness, insufficient efficiency, serious efficiency roll‐off. In this study, pair octahydro‐binaphthol ( OBN )‐based chiral emitting enantiomers, R / S )‐OBN‐Cz , developed by ingeniously merging source luminophore skeleton. These...

Although per- and polyfluoroalkyl substances (PFASs) have always been a key issue in the global environmental field, there are still lot of undiscovered PFASs environment due to new PFAS alternatives developed by manufacturers. Wastewater treatment plants (WWTPs), as one sources for PFASs, an important part process releasing into environment. In this study, suspect screening homologue analysis with quadrupole time-of-flight tandem mass spectrometry were used discover wastewater from WWTP...

Reductive cross-coupling of primary amines and alkyl halides goes through a radical change.

A efficient and sustainable approach for the synthesis of 3-alkylquinoxalin-2(1H)-ones has been developed through visible-light-mediated decarboxylative alkylation quinoxalin-2(1H)-ones with phenyliodine(III) dicarboxylates. This photocatalytic reaction could be conducted at ambient temperature by employing eco-friendly PEG-200 as medium. Various were easily obtained present ruthenium(II) catalytic system, which successfully recycled five times without significant decrease its efficiency.

This work describes a nickel-catalyzed Ullmann-type thiolation of aryl iodidesunder mild electrochemical conditions. The simple undivided cell with graphene/nickel foam electrode setups offers excellent substrate tolerance, affording and alkyl sulfides in good chemical yields. Furthermore, the mechanism for this cross-coupling reaction has been investigated by cyclic voltammetry.

The CF 2 group has found applications as a substituent in all classes of organic chemical products from medicinal to materials, although it is less frequently encountered than the C–F and 3 substituents. In this review, geometric influence placing two fluorine atoms on carbon considered particular, deviations tetrahedral geometry are noted. incorporation into phosphonates phosphate mimics reviewed steric influences when placed within aliphatic chains ring (cyclododecane) systems.

A facile, practical and environmentally attractive protocol for the direct diversification of N-heterocycles under ambient, metal- base-free conditions was developed.

Pure organic materials with intrinsic room-temperature phosphorescence typically rely on heavy atoms or heteroatoms. Two different strategies towards constructing (RTP) species based upon the through-space charge transfer (TSCT) unit of [2.2]paracyclophane (PCP) were demonstrated. Materials bromine atoms, PCP-BrCz and PPCP-BrCz, exhibit RTP lifetime around 100 ms. Modulating PCP core non-halogen-containing electron-withdrawing units, PCP-TNTCz PCP-PyCNCz, successfully elongate to 313.59...

Chiral materials with circularly polarized luminescence (CPL) are potentially applicable for 3D displays. In this study, by decorating the pyridinyl-helicene ligands -CF3 and -F groups, platinahelicene enantiomers featured superior configurational stability, as well high sublimation yield (>90 %) clear CPPL properties, dissymmetry factors (|gPL |) of approximately 3.7×10-3 in solution about 4.1×10-3 doped film. The evaporated phosphorescent organic light-emitting diodes (CP-PhOLEDs) two...

Difunctionalization of olefins represents a powerful synthetic tool and yet challenging task. This work describes an electrochemically enabled fluoroalkylation–migration reaction unactivated in the absence strong oxidant or heavy metal catalyst, affording fluorinated (hetero)aryl ketones good yields excellent regioselectivities. The efficient sustainable electrochemical strategy provides rapid access to dual functionalized fluorine-containing heterocyclic manifold.

Abstract Herein, visible‐light‐driven iron‐catalyzed nitrene transfer reactions with dioxazolones for intermolecular C(sp 3 )‐N, N=S, and N=P bond formation are described. These occur exogenous‐ligand‐free process feature satisfactory to excellent yields (up 99 %), an ample substrate scope (109 examples) under mild reaction conditions. In contrast intramolecular C−H amidations strategies, regioselective amidation via visible‐light‐induced is devised. Mechanistic studies indicate that the...

The C-O bond cleavage for activation of alcohols is synthetically useful and practically challenging. This work describes carbazate as a new type electrochemically activated alkylating agent derived from ubiquitous direct functionalization heteroarenes under mild electrolytic conditions. simple undivided cell at low oxidative potentials with carbon/platinum electrode set-ups offers excellent substrate tolerance, affording variety primary, secondary tertiary alkyl-decorated heterocycles in...

Electrochemical fluorination (ECF) refers to the introduction of fluorine-containing moieties into organic molecules under electrochemical conditions.

Electrosynthesis has received great attention among researchers in both academia and industry as an ideal technique to promote single electron reduction without the use of expensive catalysts. In this work, we report electrochemical Katritzky salts alkyl radicals by sacrificing easily accessible metal anode. This catalyst electrolyte free platform broad applicability transfer chemistry, including fluoroalkenylation, alkynylation thiolation. The deaminative functionalization is facilitated...

Sulfonyl fluorides are key components in the fields of chemical biology, materials science and drug discovery. In this line, highly active SO2F radical has been employed for construction sulfonyl fluorides, but utilization gaseous ClSO2F as precursor is limited due to tedious hazardous preparation. Meanwhile, synthesis from inert SO2F2 gas through a fluorosulfonyl (·SO2F) process met with inevitable difficulties high homolytic bond dissociation energy S(VI)-F bond. Here we report...

In this study, we report the first circularly polarized white organic light-emitting diodes (CP-WOLEDs) based on all thermally activated delayed fluorescence (TADF) materials. Two pairs of spiro-type TADF enantiomers, (R/S)-SPOCN (5,5'-((2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diyl)bis(oxy))bis(4-(10H-phenoxazin-10-yl)phthalonitrile)) and (R/S)-OSFSO (2'-(trifluoromethyl)-spiro[quinolino[3,2,1-kl]phenoxazine-9,9'-thioxanthene]-10',10'-dioxide), serve as emitters with complementary...

A Markovnikov-selective hydroacylation of alkenes has been achieved via the synergistic merger cobalt, photoredox and N-heterocyclic carbene catalysis. The closely incorporated catalytic cycles allow for Co(III) generation by photochemical oxidation instead chemical oxidants or anodizing process. This mild, operationally simple protocol converts a wide variety commercially available aroyl fluorides into corresponding ketones in high yield with branched selectivity.

Abstract Direct seawater hydrogen production via electrolysis would be a transformative technology for large‐scale pathways future sustainable energy systems. However, prohibiting the formation of insoluble hydroxides and promoting proton supply at electrode‐seawater interface are extremely desirable but remain challenging. Herein, inspired by dual‐metal pair sites in natural enzyme, de novo design an efficient, robust, precise electron‐donating Cu‐modulated ruthenium clusters on porous...

Redox-active esters (RAEs) as alkyl radical precursors have been extensively developed for C-C bond formations. However, the analogous transformations of fluoroalkyl radicals from corresponding acid or ester remain challenging because high oxidation potential carboxylate anions. The newly N-hydroxybenzimidoylchloride (NHBC) provides a general leaving group assisted strategy to generate portfolio radicals, and can be successfully applied in photoinduced decarboxylative hydrofluoroalkylation...

Two circularly polarized delayed fluorescent materials were applied in non-doped and doped CP-OLEDs with |<italic>g</italic>_EL| up to 2.9 × 10⁻³, an EQE_max of 12.4% a low efficiency roll-off.