The drug delivery system based on supramolecular vesicles that were self-assembled by a novel host–guest inclusion complex between water-soluble pillar[6]arene (WP6) and hydrophobic ferrocene derivative in water has been developed. complexation WP6 was studied 1H NMR, UV–vis, fluorescence spectroscopy, which showed high binding constant of (1.27 ± 0.42) × 105 M–1 with 1:1 stoichiometry. This resulting could self-assemble into displayed significant pH-responsive behavior aqueous solution,...

Based upon the (3,6)-connected metal-organic framework {Cu(L1)·2H(2)O·1.5DMF}(∞) (L1 = 5-(pyridin-4-yl)isophthalic acid) (SYSU, for Sun Yat-Sen University), iso-reticular {Cu(L2)·DMF}(∞) (L2 5-(pyridin-3-yl)isophthalic (NJU-Bai7; NJU-Bai Nanjing University Bai group) and {Cu(L3)·DMF·H(2)O}(∞) (L3 5-(pyrimidin-5-yl)isophthalic (NJU-Bai8) were designed by shifting coordination sites of ligands to fine-tune pore size polarizing inner surface with uncoordinated nitrogen atoms, respectively,...

Abstract Circularly polarized organic light‐emitting diodes (CP‐OLEDs) are particularly favorable for the direct generation of CP light, and they demonstrate a promising application in 3D display. However, up to now, such devices have suffered from low brightness, insufficient efficiency, serious efficiency roll‐off. In this study, pair octahydro‐binaphthol ( OBN )‐based chiral emitting enantiomers, R / S )‐OBN‐Cz , developed by ingeniously merging source luminophore skeleton. These...

Reductive cross-coupling of primary amines and alkyl halides goes through a radical change.

Abstract A spiro‐axis skeleton not only introduces circularly polarized luminescence (CPL) into thermally activated delayed fluorescence (TADF) molecules but also enhances the intramolecular through space charge transfer (TSCT) process. Spiral distributed phenoxazine and 2‐(trifluoromethyl)‐9 H ‐thioxanthen‐9‐one‐10,10‐dioxide act as donor acceptor units, respectively. The resulting TADF enantiomers, ( rac )‐OSFSO, display emission maxima at 470 nm, small singlet‐triplet energy gap (Δ E ST )...

Copper-catalyzed cross-dehydrogenative coupling (CDC) reactions of (benzo)thiazoles with cyclic ethers were developed under mild conditions. In particular, the formation C–C bonds via CDC between non-benzo-fused azoles and are reported for first time. addition, acetals, known as masked 2-thiazolecarboxaldehydes, could be successfully obtained by this reaction. The preliminary mechanism supportive DFT calculations discussed well.

Two novel chiral metal-organic open frameworks with unprecedented multiwalled tubular channels and interweaving of single-helical unequal double-helical units were reported, which possess four-connected 4(2)8(3)10 topology represent the first examples functional based on both flexible tripodal bisdentate ligands.

Aiming to improve the acetylene (C2H2) storage capability of MOFs, we successfully designed NJU-Bai 17, a new analogue MOF-505 with an inserted amide functional group which exhibits almost record high C2H2 uptakes 222.4 cm(3) g(-1) at 296 K and 273 under 1 bar. This result has been further supported by determination heat adsorption Grand Canonical Monte Carlo (GCMC) first-principle calculations.

An unexpected Cu-catalyzed deoxygenative C2-sulfonylation reaction of quinoline N-oxides in the presence radical initiator K2S2O8 was developed that used sodium sulfinate as a sulfonyl coupling partner. The mechanism studies indicate proceeds via Minisci-like step to give sulfonylated with good chemical yields.

Abstract We present a crystal engineering strategy to fine tune the pore chemistry and CH 4 ‐storage performance of family isomorphic MOFs based upon PCN‐14. These exhibit similar size, surface, surface area (around 3000 m 2 g −1 ) were prepared with goal enhance working capacity. [Cu (L2)(H O) ] n (NJU‐Bai 41: NJU‐Bai for Nanjing University Bai's group), (L3)(H 42), (L4)(DMF) 43) we observed that volumetric capacity uptake values are influenced by subtle changes in structure chemistry. In...

This work describes a nickel-catalyzed Ullmann-type thiolation of aryl iodidesunder mild electrochemical conditions. The simple undivided cell with graphene/nickel foam electrode setups offers excellent substrate tolerance, affording and alkyl sulfides in good chemical yields. Furthermore, the mechanism for this cross-coupling reaction has been investigated by cyclic voltammetry.

CO2 capture science and technology, particularly for the post-combustion capture, has become one of very important research fields, due to great concern global warming. Metal-organic frameworks (MOFs) with a unique feature structural fine-tunability, unlike traditional porous solid materials, can provide many powerful platforms explore high-performance adsorbents capture. Until now, several strategies finely tuning MOF structures have been developed, in which either larger quadrupole moment...

A photoredox and copper catalyzed asymmetric cyanoalkylation reaction of alkenes has been developed, which uses alkyl N-hydroxyphthalimide esters as alkylation reagents. In this radical reaction, the induced adds to styrene, generated benzylic couples with a chiral Box/CuII cyanide complex achieve enantioselective cyanation. This features mild conditions, operational simplicity, broad substrate scope, high yields, enantioselectivities, represents an efficient method for difunctionalization alkenes.

Chiral materials with circularly polarized luminescence (CPL) are potentially applicable for 3D displays. In this study, by decorating the pyridinyl-helicene ligands -CF3 and -F groups, platinahelicene enantiomers featured superior configurational stability, as well high sublimation yield (>90 %) clear CPPL properties, dissymmetry factors (|gPL |) of approximately 3.7×10-3 in solution about 4.1×10-3 doped film. The evaporated phosphorescent organic light-emitting diodes (CP-PhOLEDs) two...

A bis-urea-functionalized pillar[5]arene has been synthesized and shown to form [2]pseudorotaxanes spontaneously with linear alkyl dicarboxylates in highly polar solvent DMSO, which the hydrogen bonding interactions between bis-urea hydrogens dicarboxylate oxygens play an important role stabilizing novel alongside C–H⋯π interactions.

Abstract In the present work, an asymmetric copper‐catalyzed radical multi‐component cascade reaction of unsaturated carboxylic acid, aryldiazonium tetrafluoroborate, and DABCO⋅(SO 2 ) (DABSO) has been developed for enantioselective synthesis sulfonyl lactones. this reaction, SO surrogate, DABSO was applied first time in construction chiral compounds. This multiple‐step carried out under mild conditions tolerated a wide range substrates, resulting corresponding lactones with up to 95%...

An iron-catalyzed oxidative esterification reaction between unactivated C(sp(3))-H bonds from symmetric and asymmetric ethers carboxylic acids using di-tert-butyl peroxide (DTBP) as the oxidant via a cross dehydrogenative coupling (CDC) was established, which tolerates wide range of cyclic ether substrates to react with aromatic phenylacetic acid, providing an efficient method for preparation α-acyloxy good excellent yields. Intermolecular competing kinetic isotope effect (KIE) experiments...

A Ni-catalyzed reductive cross-coupling reaction between two electrophiles, amides and aryl iodides, has been developed. This work is the first example using amide as an electrophile to couple with another electrophile, instead of highly basic pyrophoric nucleophiles. Furthermore, Ni catalyst chemoselectively inserting C-N bond triggered reaction, which solves problem that preferentially inserts more reactive C-I form a self-coupling product.

A new approach of finely tuning multinuclear clusters metal–organic frameworks (MOFs) through symmetry-upgradingly isoreticular transformation was first presented and a bcu-type MOF, {[Cu4(μ4-O)Cl2(IN)4][CuCl2]}∞ (NJU-Bai35; NJU-Bai for Nanjing University Bai group), with cluster [Cu4(μ4-O)Cl2(COO)4N4] higher symmetry compared to the pristine successfully synthesized. The upgrading implemented on inorganic part triggers adjustment channels in NJU-Bai35 fit CO2 molecules, leading high...

A linear pillar[5]arene-modified conjugated polymer was synthesized, and novel side-chain polypseudorotaxanes were formed via the host–guest interactions between pillar[5]arene unit n-octylpyrazinium salt. Compared with which shows strong fluorescence, show very weak fluorescence due to efficient electron transfer from backbone cation. Moreover, upon addition of chloride anion solution polypseudorotaxanes, a disassembly process occurred, leading recovery polymer. Therefore, could serve as an...

Abstract A Cu‐catalyzed asymmetric detrifluoroacetylative aldol addition reaction of 2‐fluoro‐1,3‐diketones/hydrates to aldehydes in the presence base and chiral bidentate ligand was developed. The carried out under convenient conditions tolerated a wide range substrates, resulting fluorinated quaternary stereogenic α‐fluoro‐β‐hydroxy ketone products with good chemical yields, diastereo‐ enantioselectivities. This catalytic provides new approach for preparation biologically relevant...

Difunctionalization of olefins represents a powerful synthetic tool and yet challenging task. This work describes an electrochemically enabled fluoroalkylation–migration reaction unactivated in the absence strong oxidant or heavy metal catalyst, affording fluorinated (hetero)aryl ketones good yields excellent regioselectivities. The efficient sustainable electrochemical strategy provides rapid access to dual functionalized fluorine-containing heterocyclic manifold.

The first example of the electrochemical oxysulfuration reaction alkenes with thiols and nucleophilic oxygen sources has been reported.

An oxidative C(sp(3))-H bond functionalization of alkanes and alkylation-initiated radical 1,2-aryl migration in α,α-diaryl allylic alcohols using di-tert-butyl peroxide (DTBP) as the oxidant was established, which tolerates a wide range simple alkane substrates for direct preparation α-aryl-β-alkylated carbonyl ketones.