Electroorganic synthesis is an emerging area of high impact research in organic chemistry, which considered as one the green and efficient methods attracts growing attention. In this review, we summarized comprehensively recent literature reports on electrochemical oxidative difunctionalization unsaturated C—C bonds. The reaction types described review included intermolecular cyclization, intramolecular alkenes/alkynes. This focuses discussion its synthetic generality for preparation...

An unexpected Cu-catalyzed deoxygenative C2-sulfonylation reaction of quinoline N-oxides in the presence radical initiator K2S2O8 was developed that used sodium sulfinate as a sulfonyl coupling partner. The mechanism studies indicate proceeds via Minisci-like step to give sulfonylated with good chemical yields.

A photoredox and copper catalyzed asymmetric cyanoalkylation reaction of alkenes has been developed, which uses alkyl N-hydroxyphthalimide esters as alkylation reagents. In this radical reaction, the induced adds to styrene, generated benzylic couples with a chiral Box/CuII cyanide complex achieve enantioselective cyanation. This features mild conditions, operational simplicity, broad substrate scope, high yields, enantioselectivities, represents an efficient method for difunctionalization alkenes.

Abstract In the present work, an asymmetric copper‐catalyzed radical multi‐component cascade reaction of unsaturated carboxylic acid, aryldiazonium tetrafluoroborate, and DABCO⋅(SO 2 ) (DABSO) has been developed for enantioselective synthesis sulfonyl lactones. this reaction, SO surrogate, DABSO was applied first time in construction chiral compounds. This multiple‐step carried out under mild conditions tolerated a wide range substrates, resulting corresponding lactones with up to 95%...

A Ni-catalyzed reductive cross-coupling reaction between two electrophiles, amides and aryl iodides, has been developed. This work is the first example using amide as an electrophile to couple with another electrophile, instead of highly basic pyrophoric nucleophiles. Furthermore, Ni catalyst chemoselectively inserting C-N bond triggered reaction, which solves problem that preferentially inserts more reactive C-I form a self-coupling product.

The first example of the electrochemical oxysulfuration reaction alkenes with thiols and nucleophilic oxygen sources has been reported.

An efficient photocatalytic oxidative/reductive cyclization reaction of N-cyanamide alkenes with arylsulfinic acids or arylsulfonyl chlorides, which proceeds through C–S, C–C, and C–N bond formations, is reported. This was carried out under mild conditions, provides a new strategy for the synthesis sulfonated quinazolinones. Furthermore, one-pot procedure to achieve terminal has been explored via elimination obtained quinazolinones basic conditions.

Recent advances in the oxidative reactions of sulfinate salts under electrochemical conditions, and reaction mechanism are discussed.

Comprehensive Summary A novel electrochemical multicomponent cascade reaction of indole‐tethered alkenes with CF 3 SO 2 Na and n ‐Bu 4 NI has been developed, which enables the rapid assembly spiropyrrolidinyl‐oxindoles in good yields. The experimental results DFT calculations suggest that this proceeds through oxidation Na, radical coupling alkene, spirocyclization, sulfinate, iodide substitution, water coupling. This strategy features mild conditions, easy‐to‐handle reactants, chemical...

We report the green, sunlight-initiated radical conversion of aryl alkynoates to 3-iodocoumarins using NIS without use a catalyst or additive. Mechanistic studies indicate that reaction proceeds through iodination, spirocyclization and ring expansion form kinetic product.

Abstract Detrifluoroacetylative generation of fluoro enolates is an emerging area high‐impact research. In this review article we provide, for the first time, a comprehensive and critical treatment subject. The reaction types reported to date include Mannich, aldol, Michael addition halogenation reactions. These processes can be very successfully conducted in asymmetric fashion, stoichiometric or catalytic mode. general, these reactions allow synthetically rather simple practical...

A cascade visible-light photocatalytic difluoroalkylation and intramolecular cyclization reaction has been developed for the synthesis of difluoroalkylated oxygen heterocycles. The was carried out under very mild conditions, affording fluorinated isobenzofuran-1-ones, lactone, cyclic ethers with up to 97% chemical yields. Furthermore, several types bromofluoroalkane precursors bearing ester, keto, amido, phosphate groups could all work well in this reaction, which provides an easy method...

A metal-free hydroxyalkylation-initiated radical six-membered heterocycle formation reaction of N-allylbenzamide is developed. This proceeds through C(sp(3))-H bond cleavage, oxyalkylation the double bond, and intramolecular cyclization, which provides a new route toward 4-substituted 3,4-dihydroisoquinolin-1(2H)-one derivatives.

A coupling reaction for the synthesis of sulfonohydrazides from two types hydrazines and K₂S₂O₅ under air was developed.

An efficient cascade trifunctioalization reaction of alkynoates with N-iodosuccinimide has been developed which proceeds through iodination, aryl migration, decarboxylation, and second iodination. This represents an example 1,1-difunctionalization the acetylene bond also provides a new strategy for preparation 1,1-diiodoalkenes.

An electrochemical homo-coupling reaction of imidazopyridine heterocycles has been developed for the synthesis biheteroaryls. This features good compatibility, high yields and excellent regioselectivities, which provides an efficient access to biheteroaryl compounds.

An eco-friendly and efficient method for the synthesis of organophosphinates via an electrochemical cross-dehydrogenative-coupling reaction between alcohols secondary phosphine oxides has been developed. This was conducted at room temperature without addition any oxidant, metal catalyst, or additive, which provides a new strategy organophosphinates.