A5055581828- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Neurodevelopmental Disorders
- Stress Responses and Cortisol
- Autism Spectrum Disorder Research
- Estrogen and related hormone effects
- Genetic and phenotypic traits in livestock
- Receptor Mechanisms and Signaling
- Neurogenesis and neuroplasticity mechanisms
- Neurobiology and Insect Physiology Research
- Neuroendocrine regulation and behavior
- Adipose Tissue and Metabolism
- Olfactory and Sensory Function Studies
- Gene expression and cancer classification
- Genetics, Bioinformatics, and Biomedical Research
- Cardiovascular Disease and Adiposity
- Cognitive Abilities and Testing
- Bioinformatics and Genomic Networks
- Hormonal Regulation and Hypertension
- Alzheimer's disease research and treatments
- Genetics and Plant Breeding
- Circadian rhythm and melatonin
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurotransmitter Receptor Influence on Behavior
Institut de Neurosciences Cognitives et Intégratives d’Aquitaine
2013-2022
Centre National de la Recherche Scientifique
2013-2022
Université de Bordeaux
2013-2022
Mayo Clinic
2021-2022
WinnMed
2021-2022
Goethe University Frankfurt
2021-2022
Shanghai University
2021-2022
Tehran University of Medical Sciences
2021-2022
Children's Medical Center
2021-2022
Ludwig-Maximilians-Universität München
2021-2022
Abstract Previous studies showed the Fmr1 knockout (KO) mouse to be an excellent animal model for human fragile‐X syndrome. The aim of this study was further characterize phenotype these animals. Neuroanatomically, KO male mice were compared wild‐types (littermates) with respect their sizes hippocampal intra‐ and infrapyramidal mossy fiber (IIPMF) terminal fields. Behaviorally, they tested in four different paradigms, each measuring aspects cognitive emotional behavior: elevated plus maze...
The active component of the acne drug Accutane is 13- cis -retinoic acid (RA), and it highly teratogenic for developing central nervous system. Very little known, however, regarding effect this on adult brain. Regions brain that may be susceptible to RA are those continue generate new neurons. In mouse, neurogenesis maintained in hippocampus subventricular zone. This report demonstrates a clinical dose (1 mg/kg/day) -RA mice significantly reduces cell proliferation zone, suppresses...
Background No animal models of autism spectrum disorders (ASD) with good construct validity are currently available; using genetic pathologies characterized by ASD-like deficits, but known causes, may be therefore a promising strategy. The Fmr1-KO mouse is an example this approach, modeling Fragile X syndrome, well-known disorder presenting ASD symptoms. available on different backgrounds (FVB versus C57BL/6), which explain some the conflicting results that have been obtained these mutants...
What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice J. N. Crawley Wiley Interscience, 2nd edn., 2007. $99.95 (hardcover), xvi + 523 pp. ISBN 978-0-471-47192-9 This book hardly needs any description. Since the first edition was published in 1999, this has become a ‘must’ for every behavioral neuroscientist working mice. The second contains many upgrades additions. only very minor quibble would be that chapter on how to produce transgenic knockout mice is not...
Since Genes, Brain and Behavior (G2B) started publication in 2002, the journal has become one of favored outlets for, among many other subjects, mouse mutant studies. Unfortunately, a significant proportion studies suffer from serious methodological problems, which are most frequent reason rejection without review for manuscripts submitted to G2B. Most these problems currently not always appreciated field authors sometimes protest such summary reject decisions by arguing that they followed...