Sousan Akrami

ORCID: 0000-0001-6643-140X
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Antibiotic Use and Resistance
  • Bacterial biofilms and quorum sensing
  • Essential Oils and Antimicrobial Activity
  • Gastric Cancer Management and Outcomes
  • Pharmacological Effects of Natural Compounds
  • Helicobacter pylori-related gastroenterology studies
  • Probiotics and Fermented Foods
  • Mycobacterium research and diagnosis
  • Long-Term Effects of COVID-19
  • Tuberculosis Research and Epidemiology
  • Phytochemistry and Biological Activities
  • Eosinophilic Esophagitis
  • Nanoparticles: synthesis and applications
  • Garlic and Onion Studies
  • Microbial Metabolites in Food Biotechnology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotics Pharmacokinetics and Efficacy
  • Urinary Tract Infections Management
  • SARS-CoV-2 and COVID-19 Research
  • Fungal Plant Pathogen Control
  • Phytochemistry Medicinal Plant Applications
  • Berberine and alkaloids research
  • Bacterial Infections and Vaccines
  • Burn Injury Management and Outcomes

Tehran University of Medical Sciences
2022-2025

Ahvaz Jundishapur University of Medical Sciences
2020-2024

Beta-lactams resistance is a major clinical problem in treating pneumonia. This study aimed to detect the extended-spectrum beta-lactamases (ESBL) genes Klebsiella pneumoniae among patients with community-acquired pneumonia (CAP) Al-Najaf City, Iraq.A total of 511 sputum samples were obtained from all suspected CAP Iraq, March 2020 September 2020. Sputum subjected microbiological tests. The disk diffusion method was used test antibiotic sensitivity. Production ESBLs identified using...

10.1590/1806-9282.20220222 article EN Revista da Associação Médica Brasileira 2022-06-01

In recent years, the resistance rate to quinolone antibiotics has been increasing in Klebsiella pneumoniae. Plasmid-mediated (PMQR) genes are one of factors causing quinolones. Hence, this study aimed determine incidence PMQR clinical K. pneumoniae isolates from southwest Iran. total, 96 were identified during period. Sixty-seven (69.8%) resistant at least antibiotic. Resistance rates levofloxacin, norfloxacin, nalidixic acid, ofloxacin, and ciprofloxacin 50% (48/96), 56.3% (54/96), 60.4%...

10.1186/s12879-025-10596-0 article EN cc-by-nc-nd BMC Infectious Diseases 2025-02-14

There is a widespread distribution of gram-negative bacteria worldwide, which are responsible for the deaths numerous patients each year. The illnesses they cause can be localized and systemic, these possess several key virulence factors that contribute to their pathogenicity. In recent years, distinct mechanisms pathogenesis have evolved remain largely unknown scientists medical experts. Among these, outer membrane vesicles (OMVs) undoubtedly one most significant influencing virulence. OMVs...

10.3389/fimmu.2025.1541636 article EN cc-by Frontiers in Immunology 2025-04-01

Abstract The Food and Drug Administration (FDA) has licensed many antiretroviral medications to treat human immunodeficiency virus type 1 (HIV-1), however, treatment options for people with multi-drug resistant HIV remain limited. Medication resistance, undesirable effects, prior tolerance, previous interlacement incapacity deliver new drug classes all lead the requirement medication combination therapy. Fostemsavir (FTR) is a CD-4 attachment inhibitor medicine that was recently authorized...

10.1186/s12879-024-09122-5 article EN cc-by BMC Infectious Diseases 2024-02-23

Abstract Background Pseudomonas aeruginosa as an opportunistic pathogen produces several virulence factors. This study evaluated the relative frequency of exoenzymes ( exo ) A, U and S genes integron classes (I, II, III) among multi‐drug‐resistant clinical P. isolates from burn patients in Ahvaz, southwest Iran. Methods In this cross‐sectional were recovered 355 wound samples. The antimicrobial susceptibility test was done by disk agar diffusion method on Muller‐Hinton according to Clinical...

10.1002/hsr2.2164 article EN cc-by-nc-nd Health Science Reports 2024-06-01

This study aims to investigate the frequency of cas1 and cas3 CRISPR1,2,3 genes in Klebsiella pneumoniae isolates, as well their connection with antibiotic resistance.

10.1186/s12879-024-10018-7 article EN cc-by BMC Infectious Diseases 2024-10-07

There are limited studies on the antibiotic resistance patterns of slowly growing mycobacteria (SGM) species and their related gene mutations in Iran. This study aimed to elucidate susceptibility profiles some genes that associated with among SGM isolates from The strains were isolated sputum samples suspected tuberculosis (TB) patients. identified by standard phenotypic tests assigned level amplification sequencing dnaK gene. minimum inhibitory concentration (MIC) eight antibiotics was...

10.1080/20477724.2022.2049029 article EN Pathogens and Global Health 2022-03-09

Abstract Background and Aims Resistance to antibiotics the capability develop biofilm as two main virulent determinants of Klebsiella pneumoniae have important role in infection persistence. The aim study was evaluate association between prevalence aminoglycoside resistance virulence genes formation capacity K. strains isolated from hospitalized patients South‐West Iran. Methods A total 114 non‐duplicate clinical isolates collected Ahvaz teaching hospitals. Identification species performed...

10.1002/hsr2.1266 article EN cc-by Health Science Reports 2023-05-01

This study aimed to evaluate the antibiotic resistance patterns and prevalence of carbapenemase genes in Klebsiella pneumoniae isolates different clinical samples from Tabriz city, northwestern Iran.This cross-sectional was conducted Department Microbiology, Islamic Azad University, Ahar Branch, Iran, 2020. K. were collected samples, including blood, wounds, sputum, urine. The identified using a series standard bacteriological tests. Antibiotic determined by disc diffusion method. presence...

10.1186/s13104-023-06558-x article EN cc-by BMC Research Notes 2023-11-03

Abstract This study investigated the bacterial causes of superinfections and their antibiotic resistance pattern in severe coronavirus disease 2019 (COVID‐19) patients admitted to intensive care unit (ICU) Razi Hospital Ahvaz, southwest Iran. In this cross‐sectional study, endotracheal tube (ETT) secretion samples 77 intubated COVID‐19 patients, confirmed by reverse transcription‐quantitative polymerase chain reaction, were standard microbiology test analytical profile index kit. Antibiotic...

10.1002/jmv.28403 article EN Journal of Medical Virology 2022-12-14

Abstract Background and Aims Multidrug extensive drug‐resistant Pseudomonas aeruginosa was extracted from burn patients referring to centers in southwest Iran so that biofilm generation antibiotic resistance could be investigated. Methods A specific primer used confirm all our considered 110 P. culture‐positive reports on 345 patients. The of seven antibiotics Colistin with minimum inhibitory concentration (MIC) assessed. Biofilm formation assessed by the phenotypic study specimens under...

10.1002/hsr2.2138 article EN cc-by-nc-nd Health Science Reports 2024-06-01

Abstract The goal of this research was to create dried fruits loaded with probiotic microorganisms ( Lactobacillus casei and plantarum ). In separate bottles for each microbe, apple banana pieces have been submerged into the impermeability solution gentle shaking. vacuum pressure applied. By conclusion incubation time, L. colonies were enumerated (CFU/g). scanning electron microscope method applied confirm penetration impregnation solutions intercellular spaces fruit tissue. On day 28,...

10.1002/jemt.24639 article EN Microscopy Research and Technique 2024-06-24

This study aimed to evaluate the association of intimin (eae) and pagC genes with biofilm formation multidrug resistance (MDR) phenotype in Escherichia coli Salmonella enterica collected from calves diarrhea.Fecal samples (n: 150) were diarrhea. Of 150 fecal samples, 122 (81.3%) culture positive 115/122 (94.2%) Gram-negative bacteria. Among them, E. (n = 64/115, 55.6%) was most common isolate followed by S. 41/115, 35.6%). Also, 10 (8.6%) isolates other Enterobacteriaceae bacteria including...

10.1186/s13104-022-06218-6 article EN cc-by BMC Research Notes 2022-10-11
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