Morteza Saki

ORCID: 0000-0001-7419-0116
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Escherichia coli research studies
  • Bacterial Identification and Susceptibility Testing
  • Antibiotics Pharmacokinetics and Efficacy
  • Helicobacter pylori-related gastroenterology studies
  • Salmonella and Campylobacter epidemiology
  • Clostridium difficile and Clostridium perfringens research
  • Essential Oils and Antimicrobial Activity
  • Pneumonia and Respiratory Infections
  • Urinary Tract Infections Management
  • Vibrio bacteria research studies
  • Tuberculosis Research and Epidemiology
  • Bacterial Infections and Vaccines
  • Computational Drug Discovery Methods
  • Water Treatment and Disinfection
  • Probiotics and Fermented Foods
  • Legionella and Acanthamoeba research
  • Infective Endocarditis Diagnosis and Management
  • Biosensors and Analytical Detection
  • Healthcare Systems and Reforms
  • Veterinary medicine and infectious diseases

Ahvaz Jundishapur University of Medical Sciences
2013-2025

Imam Khomeini Hospital
2022-2023

Institute for Health Metrics and Evaluation
2023

University of Washington
2023

Czech Academy of Sciences, Institute of Microbiology
2022

This study aimed to evaluate the presence of CRISPR-Cas system genes and their possible association with antibiotic resistance patterns Enterococcus faecalis faecium species isolated from hospital wastewater (HWW) samples several hospitals.HWW (200 mL) were collected discharged different hospitals October 2020 March 2021. The isolation identification enterococci performed by standard bacteriology tests polymerase chain reaction (PCR). Antibiotic was determined using disc diffusion. various...

10.2147/idr.s358248 article EN cc-by-nc Infection and Drug Resistance 2022-03-01

This study aimed to determine the prevalence of bacterial vaginosis (BV) and aerobic vaginitis (AV) their associated risk factors among pregnant women from Ethiopia. Also, this investigated pathogens antibiotic resistance in AV cases. A total 422 northern Ethiopia were participated study. Socio-demographic clinical data recorded. Vaginal swabs collected used for wet mount Gram stain methods evaluate BV scores according Nugent's Donder's criteria, respectively. In cases determined using...

10.1371/journal.pone.0262692 article EN cc-by PLoS ONE 2022-02-25

Abstract This study aimed to assess the presence of qnrA , qnrB qnrC qnrD qnrS qepA and aac(6′)-Ib-cr determinants as well quinolone resistance pattern clinical isolates P. aeruginosa in Ahvaz, southwest Iran. A total 185 were collected from 5 university-affiliated hospitals The disk diffusion method was applied pattern. genes investigated by polymerase chain reaction (PCR) method. Overall, 120 (64.9%) non-susceptible quinolones. most less rates observed against ciprofloxacin (59.4%)...

10.1038/s41598-022-06128-4 article EN cc-by Scientific Reports 2022-02-10

Bacterial biofilm is one of the major hazards facing food industry. Biofilm-forming ability most important virulence properties enterococci. The genus Enterococcus includes pathogenic, spoilage, and pro-technological bacteria. presence enterococci in milk dairy products usually associated with inadequate hygiene practices. study examined isolates' capacity for formation identification genetic determinants its among 85 strains isolated from raw (n = 49) soft-ripened cheeses made unpasteurized...

10.3390/life13020495 article EN cc-by Life 2023-02-10

To evaluate the potential probiotic properties of Lactobacillus strains isolated from feces infants and also to determine their antimicrobial activity against some enteropathogenic bacteria.The Fecal samples were prepared 120 aged less than 24 months. In total, 105 identified by phenotypic tests. Thirty isolates randomly selected study properties. These examined for resistance acid (pH: 2.5, 2 h) bile (oxgall 0.3%, 8 h), adhesion HT-29 cells, antibiotic susceptibility, activities.On basis...

10.1016/j.ijid.2020.05.034 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-05-18

Beta-lactams resistance is a major clinical problem in treating pneumonia. This study aimed to detect the extended-spectrum beta-lactamases (ESBL) genes Klebsiella pneumoniae among patients with community-acquired pneumonia (CAP) Al-Najaf City, Iraq.A total of 511 sputum samples were obtained from all suspected CAP Iraq, March 2020 September 2020. Sputum subjected microbiological tests. The disk diffusion method was used test antibiotic sensitivity. Production ESBLs identified using...

10.1590/1806-9282.20220222 article EN Revista da Associação Médica Brasileira 2022-06-01

One of the most common viral infections worldwide is Human Papilloma Virus (HPV) which has been linked to cancer and other diseases in many countries. Monosaccharide esters are significant field carbohydrate chemistry because they efficient synthesis pharmacologically active compounds. Therefore, present study aimed perform thermodynamic, molecular docking dynamics a series previously designed monosaccharaides, methyl β-d-galactopyranoside (MGP, 1) (2–10) with along their physicochemical...

10.1080/07391102.2023.2198606 article EN Journal of Biomolecular Structure and Dynamics 2023-04-07

Abstract Helicobacter pylori is a prominent gastrointestinal pathogen associated with various illnesses. It presents substantial health risks due to its antibiotic resistance. Therefore, it crucial identify alternative treatments for H. infections. Limosilactobacillus spp exhibit probiotic properties beneficial effects in humans; however, the mechanisms by which counteracts infection are unknown. This study aimed evaluate potential of fermentum T0701 lyophilized cell-free supernatants (LCFS)...

10.1038/s41598-024-64443-4 article EN cc-by Scientific Reports 2024-06-13

In recent years, the resistance rate to quinolone antibiotics has been increasing in Klebsiella pneumoniae. Plasmid-mediated (PMQR) genes are one of factors causing quinolones. Hence, this study aimed determine incidence PMQR clinical K. pneumoniae isolates from southwest Iran. total, 96 were identified during period. Sixty-seven (69.8%) resistant at least antibiotic. Resistance rates levofloxacin, norfloxacin, nalidixic acid, ofloxacin, and ciprofloxacin 50% (48/96), 56.3% (54/96), 60.4%...

10.1186/s12879-025-10596-0 article EN cc-by-nc-nd BMC Infectious Diseases 2025-02-14

Infections caused by extended-spectrum β-lactamases (ESBLs) producing bacteria, including Klebsiella pneumoniae have increasingly subjected to therapeutic limitations and patients with these infections are at high risk for treatment failure, long hospital stays, health care costs, mortality. The aim of this study was screen the prevalence blaTEM,blaCTX-M blaSHV ESBL genes in K. strains isolated from nosocomial urinary tract (UTIs). During March 2016 December 2017, one hundred isolates were...

10.1016/j.heliyon.2019.e02349 article EN cc-by-nc-nd Heliyon 2019-09-01

The COVID-19 pandemic, caused by SARS-CoV-2, has globally affected both human health and economy. Several variants with a high potential for reinfection the ability to evade immunity were detected shortly after initial reported case of COVID-19. A total 30 mutations in spike protein (S) have been SARS-CoV-2 (BA.2) variant India South Africa, while half these are receptor-binding domain spread rapidly throughout world. Drug repurposing offers advantages over discovery novel drugs, one is that...

10.1016/j.imu.2023.101281 article EN cc-by Informatics in Medicine Unlocked 2023-01-01

Enteroaggregative Escherichia coli (EAEC) has been implicated as an emerging cause of traveler's diarrhea, persistent diarrhea among children, and immunocompromised patients. The present study aimed to investigate the prevalence antibiotic resistance, extendedspectrum β-lactamase (ESBL) production, virulence factors EAEC isolates obtained from Iranian children suffered diarrhea.In this cross-sectional study, March 2015 February 2016, 32 were collected fecal samples aged <12 years with in...

10.2147/idr.s167271 article EN cc-by-nc Infection and Drug Resistance 2018-08-01

The spread of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli has increased in different environments. This study aimed to evaluate the patterns antibiotic resistance and ESBL genes among E. isolates collected from wastewater recipient surface water South Africa. Fifteen samples containing nine six river were a local treatment plant. detected using standard microbiology methods. Antibiotic susceptibility testing was performed disc diffusion agar. occurrence blaCTX-M, blaSHV...

10.1016/j.nmni.2020.100803 article EN cc-by-nc-nd New Microbes and New Infections 2020-10-31

Shigellosis is a significant global human health problem, and Shigella in charge of almost 165 million cases this disease annually, whom 163 are developing countries 1.5 developed countries. The main aims the current survey were to identify spp. isolated from diarrheal patients by conventional biochemical tests, determine antimicrobial susceptibility profiles disk diffusion method, detect ipaH gene using PCR assay.The bacterial isolates identified as microbiological tests serogrouped slide...

10.2147/idr.s187861 article EN cc-by-nc Infection and Drug Resistance 2019-01-01
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