The present study investigates the antioxidant and hepatoprotective effects of

Postprandial hyperglycemia plays an important role in the development of type 2 diabetes. Inhibition alpha-amylase was led to a delay breaks down starch and glycogen prevented rapid rise blood sugar. Alpha-amylase isolated by gel filtration chromatography Sephadex G-75 from bovine pancreas. Then, total methanolic extracts plants were prepared IC 50 values on obtained compared with acarbose . The polyphenolic content antioxidant capacity determined Folin-Ciocalteu test DPPH test,...

Abstract Objective To assess the efficacy and tolerability of ondansetron in combination with selective serotonin reuptake inhibitors (SSRIs) patients obsessive‐compulsive disorder (OCD). Methods The study was an 8‐week pilot double‐blind randomized clinical trial. Forty‐two adult outpatients who met Diagnostic Statistical Manual, Fourth Edition, Text Revision (DSM‐IV‐TR) criteria for OCD based on structured interview participated In this study, were randomly assigned to receive either (4...

Total phenolic and flavonoid contents antioxidant activity of four Iranian herbs (Lamiaceae) were investigated. The methanol extracts thyme (Thymus daenensis Celak.), Bakhtiari savory (Satureja bachtiarica Bung.), dragonhead (Dracocephalum multicaule Montbr & Auch), woundwort (Stachys lavandulifolia Vahl.) was evaluated by measuring 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing/antioxidant power (FRAP), trolox equivalent capacity (TEAC). A comparison all plant in the DPPH assay...

Paraoxonase 1 (PON1) is a high- density lipoprotein (HDL)-associated enzyme, displaying esterase and lactonase activity. The PON1 involved in variety of inflammatory diseases, metabolizing toxic oxidized lipids detoxifying organophosphorus insecticide compounds nerve agents.The aim this study was to investigate the effects methanolic date seed extract (DSE) on paraoxonase arylesterase activities hypercholesterolemic rats.Experiments were conducted two groups normal rats continued for four...

This randomized, double-blind, controlled trial (RCT) aimed to evaluate the effect of Phyllanthus Emblica (Amla) as an add-on therapy on COVID-19_ related biomarkers and clinical outcomes in COVID-19 patients.In this RCT, sixty-one patients were randomly assigned into two arms [the intervention (n=31) control (n=30)]. The Amla diagnostic Reverse-transcription Polymerase Chain Reaction (RT-PCR) test results between first last days study, length stay (LOS) hospital, percentage lung involvement...

This study aimed to assess the effect of date palm (Phoenix dactylifera) seed (DPS) extract at 0.5%, 1%, 2% and 4% as a dietary supplement over 60 days, on growth immune-physiology common carp (Cyprinus carpio) fingerlings. The weight gain in fish fed with 0.5% DPS was significantly greater than other treatments control diet no (p < 0.05). With increasing dosage above rate gradually declined. Feed conversion ratio lower treatments, but not so, except for highest concentration (4%). respect...

The present study aimed to investigate the protective effects of two potent natural antioxidants, gallic acid and quercetin as single or combination treatment against bleomycin-induced pulmonary fibrosis (PF). A total 50 Wistar rats were randomly divided into 5 groups. Group 1 2 intratracheally received saline bleomycin (7.5 UI/kg), respectively, on day 7, accompanied by oral administration for 28 day. Groups 3, 4, a dose acid, quercetin, their combination, Finally, lungs removed biochemical...

Background: Di-(2-ethylhexyl) phthalate (DEHP) is a well-known endocrine-disrupting compound inducing degeneration of testes. Gallic acid (GA) polyphenol with various pharmacological properties, including antioxidant and anti-inflammatory effects.Purpose: This research evaluated effects different doses GA on DEHP-induced testicular injury in adult mice.Research Design: Male mice were randomly divided into five groups treated agents for two weeks; group (I) received normal saline corn oil (5...

Abstract Heracleum lasiopetalum Boiss, Kelussia odoratissima Mozaff., and Echinophora platyloba DC. belong the Apiaceae family. They are Iranian endemic plants. These three herbs have been used as food additives in traditional preparations such pickles. Antioxidant activity (AA) of methanol extracts (ME) plants was evaluated by assays, including DPPH, FRAP, TEAC. From all comparing MEs for their IC50 EC1 values, E. had highest AA. Total phenolic content (TPC) ranged from 74 to 120 mg TAE/g....

Phthalates such as di (2-ethylhexyl) phthalate (DEHP) are well known exogenous substances, disrupting reproductive system function and structure. The current research demonstrated the effect of ellagic acid (EA) on DEHP-induced testicular injury in mice.Thirty-five healthy adult male mice were randomly divided to five groups; normal saline receiving group, DEHP (2 g/kg/day, dissolved corn oil, p.o.) EA groups (25, 50 100 mg/kg/day, p.o.). Treatment duration animals was 14 days. Body testes...

Background: The application of natural antimicrobial and antioxidant agents in food pharmaceutical products has recently become a trend due to the high demand for them from consumers. Postbiotics are bioactive compounds that produced when healthy bacteria gut ferment fiber. Objectives: This study aimed compare antibacterial properties postbiotics 5 different lactic acid (LAB) including Lactiplantibacillus fermentum, plantarum, rhamnosus, Lactobacillus casei, acidophilus. Methods: Two methods...

Menopause is an important stage in the life of every woman. Hot flashes are most common climacteric symptom and a major cause suffering postmenopausal women. Licorice one plants that used to relieve menopausal symptoms. The present study was undertaken evaluate effects licorice on hot flash symptoms participants this randomized, double blind, clinical trial were 60 women randomly allocated or hormone replacement therapy (HRT) groups. received (1140 mg/day) HRT (a conjugated estrogen 0.312...

Background: The mosquitoes of Culicidae family are serious vectors several tropical diseases, such as malaria, filariasis, encephalitis, and nuisance. Control protection people from their bites the most important ways to prevent transmitted diseases. Although efficacy N, N-diethyl-m-toluamide (DEET) is high generally used mosquito repellent, yet a number biting diptera tolerant DEET. Furthermore, there concerns about safety DEET its allergic toxic effects. Therefore, it necessary use other...

Systemic and topical treatment options against Leishmaniasis are limited to a few drugs with inconsistent efficacy unacceptable side effects none of them is suitable for all forms the disease.The aim this study was search in vitro activity green tea extract L. major promastigotes compare it glucantime.Extract prepared by percolation method. The dried dissolved DMSO 1% solvent. Leishmania treated 6 concentrations (3, 6, 12, 24, 48, 96 mg/ml) extract. As control positive group glucantime 85...

Background: Skin burn is one of the most common complications and it still considered as a major public health issue throughout world. Objectives: This experiment was conducted in order to study effects Capparis spinosa leaves extract (CSLE) cream compared with silver sulfadiazine (SSD) heal wounds rats. Methods: Different parts plant (fruit, petals) were examined for antioxidant activity by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay leave chosen preparation CSLE cream. Ninety adult male...

Background: Side effects of chemical preservatives and drug resistance have raised interests in the use natural derived from plants. Objectives: The aim this study was to examine possible antibacterial Mentha spicata L., Cuminum cyminum L. longifolia essential oils (EOs) individually combination with sodium benzoate against Escherichia coli O157:H7 Listeria monocytogenes. Methods: In experimental study, EOs were obtained analyzed by gas chromatography mass spectrometry. Disc diffusion broth...