Abstract Chronic arsenic (As) exposure, mainly as a result of drinking contaminated water, is associated with cardiovascular diseases. Mitochondrial dysfunction, oxidative stress, inflammation, apoptosis, and autophagy have been suggested the molecular etiology As cardiotoxicity. Melatonin (Mel) powerful antioxidant. Mel improves diabetic cardiomyopathy, cardiac remodeling, heart failure. Following pre‐treatment (10, 20, or 30 mg/kg/day i.p.), rats were orally gavaged (15 mg/kg/day) for 28...

Abstract: Our objective was to study skin disorders in neonates within the first 48 hours of life Ahvaz, Iran. One thousand consecutive were examined a descriptional prospective cohort for 1 year (2002–03). The rate and their relationship age gestation sex calculated analyzed using computerized program spss version 10 chi‐squared test (χ 2 ). findings Mongolian spots (71.3%), Epstein pearls (70.2%), sebaceous hyperplasia (43.7%), salmon patch (26.2%), hypertrichosis (25.7%), erythema toxicum...

Background: Reducing the wound healing time is crucial in as it lowers chance of infection and decreases complications cost. Grape seed extract has ability to release endothelial growth factor its topical application results contraction closure skin wound. Furthermore, possesses antioxidant antibacterial properties. In several studies been proved effective animals. Therefore, due low side effects recognition herbal medicine, we decided evaluate effect grape 2% cream on human lesions....

The blood-red sap of Dragon's blood has been used in folk medicine for fractures, wounds, inflammation, gastrointestinal disorders, rheumatism, circulation dysfunctions, and cancer. Existing vitro vivo bioactivity this herb on different mechanisms healing shows strong potential wound healing. This clinical trial study was designated to evaluate the effect human wounds. Sixty patients, between ages 14-65 years, who were referred remove their skin tag, assigned double-blind,...

Chronic kidney disease (CKD)-associated pruritus is a significant clinical symptom affecting more than 50% of patients on hemodialysis. The availability effective therapeutic options for management CKD-associated remains treatment challenge.The aim this study was to compare cromolyn sodium cream 4% with placebo the renal pruritus.A randomized, double-blind, prospective, 4-week designed. 60 ESRD in our dialysis ward were randomly allocated or placebo. All them completed period and their...

The purpose of the present study was to evaluate and assess capability Zataria multiflora, Geranium herbarium, Eucalyptus camaldolensis essential oils in treating Saprolegnia parasitica–infected rainbow (Oncorhynchus mykiss) trout eggs. A total 150 infected eggs were collected plated on glucose-pepton agar at 24°C for 2 weeks. antifungal assay against S. parasitica determined by a macrodilution broth technique. treated with concentrations 1, 5, 10, 25, 50, 100 ppm daily three repetitions...

Arsenic (As), a metalloid chemical element, is classified as heavy metal. Previous studies proposed that As induces vascular toxicity by inducing autophagy, apoptosis, and oxidative stress. It has been shown melatonin (Mel) can decrease stress modulate autophagy in different pathological situations. Hence, this study aimed to investigate the Mel effect on As-induced through apoptosis regulation. Forty male rats were treated with (15 mg/kg; oral gavage) (10 20 mg/kg, intraperitoneally; i.p.)...

Systemic and topical treatment options against Leishmaniasis are limited to a few drugs with inconsistent efficacy unacceptable side effects none of them is suitable for all forms the disease.The aim this study was search in vitro activity green tea extract L. major promastigotes compare it glucantime.Extract prepared by percolation method. The dried dissolved DMSO 1% solvent. Leishmania treated 6 concentrations (3, 6, 12, 24, 48, 96 mg/ml) extract. As control positive group glucantime 85...

BackgroundRadiofrequency energy systems are popular options in the treatment of skin laxity and wrinkles. Fractional radiofrequency devices (FRFs) have increased efficacy safety. The thermo-contraction (TC) system is also a novel technology that can promote marked lifting effect.

Abstract Arsenic is a toxic metalloid found in the environment different organic and inorganic forms. Molecular mechanisms implicated arsenic hepatotoxicity are complex but include oxidative stress, apoptosis, autophagy. The current study focused on potential protective capacity of melatonin against arsenic‐induced hepatotoxicity. Thirty‐six male Wistar rats were allocated into control, (15 mg/kg; orally), mg/kg) plus (10, 20, 30 intraperitoneally), alone (30 groups for 28 days. After...

The aim of this work was to study the alleviative role betaine versus arsenite-provoked alterations in testis oxidative status and circulating androgenic indices. Twenty-four adult male rats (204.5 ± 21 g) were divided into four groups, equally. Control group given basal diet tap water. Group 2 received arsenite (100 mg/L) drinking Rats 3 (2% diet) during exposure. 4 at 2% period (30 days). results revealed significant decrease testicular glutathione peroxidase, catalase arsenite-treated...

SummaryInvasive aspergillosis has become an increasing problem in immunocompromised patients recent years. Due to increased antimicrobial resistance, natural agents with medicinal and immunomodulatory effects have gained more attention. Honey is a substance documented antimicrobial, anti-inflammatory wound healing effects. In this study the of three Iranian honeys on some aspects innate immunity survival rate during invasive were investigated. For purpose, mice divided into 10 groups (honey...

This study was performed to determine the effects of 8 weeks testosterone enanthate (TE) injection and resistance training (RT) on cardiac muscle in male Wistar rats. A total 28 adult rats were randomly divided into 4 groups; control + placebo, RT TE RT. Testosterone (20 mg/kg BW, IM) placebo (olive oil; 0.2 ml, injected twice a week for 2 months. The consisted climbing (5 reps/3 sets) ladder carrying load suspended from tail. serum activities aspartate aminotransferase (AST), alanine (ALT),...

Background: The therapeutic potential of honey is related to antioxidant activity against reactive oxygen species because it contains compounds such as polyphenols; therefore, we evaluated the protective effect on subacute toxicity ACR by histopathologic study tissue lesions in rat. Methods: In Ferdowsi University Mashhad, Iran, 2016, male Wistar rats were divided into 7 groups. To induce toxicity, was injected (50 mg/kg for 11 d) 5 treatment groups, received three doses 1.25, 2.5, and g/kg...