Kübra Solak

ORCID: 0000-0001-6643-3368
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About
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Research Areas
  • RNA Interference and Gene Delivery
  • Nanoparticle-Based Drug Delivery
  • Cancer Research and Treatments
  • Genetics, Bioinformatics, and Biomedical Research
  • Crystal structures of chemical compounds
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Bacteriophages and microbial interactions
  • Nanoplatforms for cancer theranostics
  • MicroRNA in disease regulation
  • Metal complexes synthesis and properties
  • Ultrasound and Hyperthermia Applications
  • Organometallic Compounds Synthesis and Characterization
  • Characterization and Applications of Magnetic Nanoparticles
  • Selenium in Biological Systems
  • SARS-CoV-2 and COVID-19 Research
  • Transgenic Plants and Applications
  • Nanoparticles: synthesis and applications
  • Sulfur Compounds in Biology
  • Mercury impact and mitigation studies
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Polymer Surface Interaction Studies
  • Intramuscular injections and effects
  • Iron oxide chemistry and applications

Atatürk University
2018-2024

Erzurum Technical University
2021-2024

Center for NanoScience
2024

Pediatrics and Genetics
2024

Trakya University
2019

Max Planck Institute for Biology of Ageing
2019

Four new carboxylates complexes with general formula R2SnL2 and R3SnL, where R = n-butyl (1, 3), methyl (2, 4) L 4-Chlorophenoxyacetate, were synthesized in significant yields. FT-IR analysis revealed a chelating (1 2) bridging bidentate (3 coordination modes for the carboxylate ligand solid state which was further confirmed by single crystal X-ray of complex 4. The NMR data (1H, 13C 119Sn) higher number around tin center compared to R3SnL 4). A close matching observed between experimental...

10.3389/fphar.2022.864336 article EN cc-by Frontiers in Pharmacology 2022-04-05

Abstract Conserved lipid transfer proteins of the Ups/PRELI family regulate accumulation in mitochondria by shuttling phospholipids a lipid-specific manner across intermembrane space. Here, we combine structural analysis, unbiased genetic approaches yeast and molecular dynamics simulations to unravel determinants specificity within conserved family. We present structures human PRELID1–TRIAP1 PRELID3b–TRIAP1 complexes, which exert activity for phosphatidic acid phosphatidylserine,...

10.1038/s41467-019-09089-x article EN cc-by Nature Communications 2019-03-08

The introduction of exogenous DNA into a cell can be used to produce large quantities protein. Here, we describe novel gene delivery method for Pichia pastoris based on recombinant using magnetic nanoparticles (MNPs) under forces. For this purpose, linear plasmid (pGKB-GFP) containing the Green Fluorescent Protein (GFP) is loaded polyethyleneimine-coated iron oxide (Fe3O4@PEI) MNPs at doses that are non-toxic yeast cells. pGKB-GFP combined with enhancer PEI (Fe3O4@PEI + PEI) directly...

10.1039/d1na00079a article EN cc-by-nc Nanoscale Advances 2021-01-01

Bacterial infections in medical devices and drug resistance of bacteria can cause chaos the world due to loss lives addition cost device revisions, quarantine, disinfection infected areas, patient treatment. Antibacterial coatings essential oils on prevent bacterial attachment reduce costs. Linalool is an antibacterial constituent oils. Herein, we examine for first time fabrication characterization radio frequency (RF) plasma polymerized hydrophilic thin films from linalool (ppLin) by...

10.3906/kim-1803-81 article EN TURKISH JOURNAL OF CHEMISTRY 2019-02-05

ABSTRACT Magnetic nanoparticles (MNPs) are produced for both diagnosis and treatment due to their simultaneous availability in magnetic resonance imaging (MRI) hyperthermia (MHT). Extensive investigations focus on developing MNPs individual MHT or MRI applications, but the development of theragnostic applications has received very little attention. In this study, through efficient examination synthesis conditions such as metal precursors, reaction parameters, solvent choices, we aimed...

10.1002/jbm.a.37817 article EN cc-by-nc Journal of Biomedical Materials Research Part A 2024-10-30

This study introduces a novel investigation of the interaction between Komagataella phaffii cells and iron oxide-based magnetic nanoparticles (Fe3O4 MNPs) via protein secretion machine learning (ML)-assisted surface-enhanced Raman scattering (SERS). For first time, we produced Fe3O4, Fe3O4@PEG, Fe3O4@PEI10kDa, Fe3O4@PEI25kDa MNPs by one-pot coprecipitation reaction. The addition polymers to reaction conditions significantly affected shape, surface charge, size, size distribution MNPs....

10.1021/acsami.4c18591 article EN cc-by ACS Applied Materials & Interfaces 2024-12-11

10.1166/nnl.2017.2389 article EN Nanoscience and Nanotechnology Letters 2017-05-01

Objective: To determine the side effects and related factors after two doses of CoronaVac vaccine in healthcare workers aged 18 to 65 years, working at hospitals Edirne’s city center. Methods: This study was a cross-sectional conducted 3 different pandemic Turkey. As May 2021, data from 530 who completed 2 were evaluated. Data collection, survey form used inquire about short-term local systemic experienced by vaccination. Results: The average age participating this 36.6±9.9 years. 44.8%...

10.53964/jmbdd.2023008 article EN Journal of Modern Biology and Drug Discovery 2023-11-08
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