A5077860405- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Blood properties and coagulation
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Artery Anomalies
- Advanced Chemical Sensor Technologies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Water resources management and optimization
- Spinal Cord Injury Research
Harefield Hospital
2022-2024
Guy's and St Thomas' NHS Foundation Trust
2022-2024
Morriston Hospital
2015-2024
Swansea Bay University Health Board
2014-2024
Swansea University
2018-2024
Royal Brompton & Harefield NHS Foundation Trust
2023
National Health Service
2021
Institut Arnault Tzanck
2017
St. Antonius Ziekenhuis
2017
Ziekenhuis Oost-Limburg
2017
Background— Small observational studies demonstrate the feasibility of transradial approach for chronic total occlusion (CTO) percutaneous coronary intervention. The aim current study is to assess technical success, complication rates, and procedural efficiency in fully (fTRA) transfemoral (TFA) a large prospective European registry adopting hybrid algorithm CTO intervention (Registry CrossBoss Hybrid Procedures France, Netherlands, Belgium United Kingdom, RECHARGE registry). Methods...
Limited data is available to guide operators as the optimal revascularisation strategy in patients with previous CABG representing angina.Retrospective analysis of 161 prior undergoing PCI two centres between September 2005 and April 2008.161 (132 male, 68 ± 8 years) underwent at 126 65 months after index CABG. Clinical presentation recurrent ischaemia was stable 59.7% an acute coronary syndrome 40.3% patients. Mean follow-up 13.5 4.8 months. About 62.7% native vessel PCI, 32.9% had a graft...
Zschauer, A. O. A., M. W. Sielczak, D. S. Smith, and Wanner. Norepinephrine-induced contraction of isolated rabbit bronchial artery: role α 1 - 2 -adrenoceptor activation. J. Appl. Physiol. 82(6): 1918–1925, 1997.—The contractile effect norepinephrine (NE) on artery rings (150–300 μm in diameter) the -adrenoceptors (AR) smooth muscle endothelium were studied. In intact arteries, NE increased tension a dose-dependent manner, sensitivity for was further absence endothelium. but not...
Severe aortic stenosis is a major cause of morbidity and mortality. The existing treatment pathway for transcatheter valve implantation (TAVI) traditionally relies on tertiary Heart Valve Centre workup. However, this has been associated with delays to treatment, in breach British Cardiovascular Intervention Society targets. A novel emphasis comprehensive patient workup at local centre, alongside close collaboration Centre, may help reduce the time TAVI.The centre performing implemented TAVI...
Introduction Prolonged dual anti-platelet therapy (DAPT) may cause excess bleeding in certain patients. The biolimus-A9 drug-coated stent (BA9-DCS) has a rapid drug-elution profile allowing shortened DAPT. Data were gathered on the early experience implanting this drug-eluting eligible patients deemed to be at high risk of bleeding. Background and Methods demographics, procedural data clinical outcomes prospectively for 249 treated with BA9-DCS 2 UK centres, compared cohort same period...
Ultrasound denervation has recently become a subject of intense research in connection with the treatment complex medical conditions including neurological conditions, development pain management, reproduction skin sensation, neuropathic and spasticity. The objective this study is to investigate use intravascular ultrasound produce nerve damage renal sympathetic nerves without significant injury artery. This technique may potentially be used treat various such as hypertension. was approved...
A 72-year-old man who had undergone coronary artery bypass grafting 18 years previously (including left internal mammary (LIMA) graft to the anterior descending artery) presented with an acute syndrome. He underwent angiography assess patency. Attempts locate origin of LIMA in subclavian were unsuccessful (figure 1A). An …
Abstract Objectives To determine whether a permanent pacemaker (PPM) in situ can enhance survival after transcatheter aortic valve implantation (TAVI), predominantly inoperable or high risk cohort. Background New conduction disturbances are the most frequent complication of TAVI, often necessitating PPM before hospital discharge. Methods We performed an observational cohort analysis UK TAVI registry (2007–2015). Primary and secondary endpoints were 30‐day post‐discharge all‐cause mortality...
<i>The UK government is considering establishing a national primary angioplasty service for patients with acute myocardial infarction. David Smith and Kevin Channer debate whether moving away from first line thrombolysis appropriate or practical</i>
To explore differences in the use of lipid lowering therapy and/or achievement guideline targets patients with and without prior depression influence sex very high-risk coronary patients.A retrospective observational cohort study was conducted using individual-level linked electronic health record data who underwent percutaneous intervention (2012-2017) Wales. The comprised 13,781 (27.4% female), 26.1% having depression. Lipid levels were recorded 10,050 whom 25% had History independently...
Increased demand for transcatheter aortic valve implantation (TAVI) procedures patients with severe stenosis has not been matched a proportional increase in available resources recent years. This article highlights the importance of developing integrated care pathways TAVI, which incorporate standardised protocols permanent pacemaker (PPI) to ensure best practice, service efficiency and reduce rates PPI post-TAVI.