- Diabetes, Cardiovascular Risks, and Lipoproteins
- Healthcare Systems and Practices
- Cervical Cancer and HPV Research
- Diet, Metabolism, and Disease
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Food composition and properties
- Liver Disease Diagnosis and Treatment
- African Botany and Ecology Studies
- HIV Research and Treatment
- HIV, Drug Use, Sexual Risk
- Natural Compound Pharmacology Studies
- HIV-related health complications and treatments
- Nutritional Studies and Diet
- Enzyme Production and Characterization
- Syphilis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Birth, Development, and Health
- Otolaryngology and Infectious Diseases
- Infections and bacterial resistance
- Child Nutrition and Water Access
- HIV/AIDS oral health manifestations
- Lipid metabolism and disorders
- Gestational Diabetes Research and Management
Université de Parakou
2013-2023
Université d'Abomey-Calavi
2016-2022
Nigeria’s rich biodiversity hosts various psychoactive plants that have been pivotal in traditional medicine and cultural practices. This review examines the medicinal uses, prevalence, mechanisms of action prominent Nigerian plants, including Datura stramonium Carica papaya. These utilized for centuries, exhibit pharmacological activities such as anti-inflammatory, analgesic, neuroactive effects, driven by their bioactive compounds like alkaloids flavonoids. Traditional applications range...
Diabetes mellitus is a chronic metabolic disorder with significant global health consequences due to its rising prevalence and associated complications. Current management strategies, such as blood glucose monitoring insulin administration, often fall short in maintaining optimal glycaemic control require high patient compliance. Nanotechnology has emerged breakthrough approach diabetes management, offering innovative solutions for continuous monitoring, targeted drug delivery, β-cell...
Human papilloma virus (HPV) infection remains a worldwide concern, especially in Sub-Saharan Africa where cervical cancer is the leading cause of death women. The aim study was to determine prevalence and genotypic distribution High-Risk HPV (HR-HPV) involved Cervical Intraepithelial Neoplasia (CIN) II III Parakou. Out total 149 samples tissues archived, fixed paraffin-embedded, 78 with histological diagnosis CIN-II, CIN-III went through deparaffinization xylene, followed by an extraction...
Pediatric bacterial meningitis (PBM) remains an important cause of disease in children Africa. We describe findings from sentinel site surveillance <5 years age the Republic Benin, 2011-2016.Cerebrospinal fluid (CSF) was collected admitted to Parakou, Natitingou, and Tanguieta hospitals with suspected meningitis. Identification Streptococcus pneumoniae (pneumococcus), Haemophilus influenzae, Neisseria meningitidis (meningococcus) performed by rapid diagnostic tests, microbiological culture,...
Introduction: Tobacco consumption alters many biological parameters, as well α-amylase activity. This research work aims to study the activity of serum and salivary alpha-amylase in habitual adult tobacco consumers. Methods: We carried out a cross-sectional descriptive analytical on 234 adults (54 smokers, 60 snuffers, chewers non-consumers). Serum was measured using kinetic enzymatic method. ANOVA, Kruskal-Wallis test were used compare averages according cases. Linear regression enabled...
Aims: To identify glycemic index (GI) and load (GL) of four local alcoholic drinks Benin in young healthy adult subjects.Study Design: An experimental study.Methodology: After ethic advice, 40 voluntary subjects (24 men, 16 women), were selected among the students University Parakou (Benin) divided into 4 groups 10.Each group consumed 100 mL one beverages (tchoukoutou, sodabi, fresh palm wine, fermented wine), alone with g whole wheat bread (50 carbohydrates).The response for 2 hours was...
Deaths linked to the consumption of plants are sometimes overlooked by health personnel in tropical environments. Parts several recognized as potentially toxic, including fruit ackee. This review paper aimed synthesize data on toxicity ackee (Blighia sapida) and a brief overview measures management its acute intoxication. was documentary analytical study. We made an analysis/synthesis articles relating poisoning with immature The PubMed, AJOL Google scholar databases were used. is plant...
The aim of this study was to determine the distribution high-risk human papillomavirus genotypes (HR-HPV) in women from general population five West African countries. This a cross-sectional descriptive study, involving 2133 nine cities countries: Benin, Burkina Faso, Cote d'Ivoire, Niger and Togo. Women were screened for precancerous cervical lesions HR-HPV infection. detection done by multiplex real-time PCR on extracted viral DNA. average age 35.06 ± 10.00 years with range 15 65 years....
Background: The administration of extracts Garcinia kola seed to experimental rats has a hypoglycemic and hepatoprotective effect.
 Objective: Assess the effect daily consumption on glycemia, creatinine serum aminotransferases among adult subjects.
 Methods: We carried out an intervention study based quasi-experimental approach during three months i.e. from May 1 July 30, 2019. A sample consisting 40 subjects (18 men, 22 women) had participated after their written consent approval...
Objectifs : L'infection au VIH constitue un problème de santé publique. La transmission mère-enfant l'un des principaux modes contamination. présente étude a pour objectif décrire les obstacles dépistage volontaire du et partage statut sérologique avec le conjoint d'une part déterminer la prévalence l'infection d'identifier facteurs associés d'autre part.Patients méthodes Il s'agit transversale à visée descriptive analytique chez gestantes suivies dans maternités Parakou. Les variables...
Background: The lipid lowering effects of Nigella sativa extracts have been reported in numerous research works. In Benin, seeds are consumed by the populations order to treat various ailments and diseases. Objective: This study was aimed assess effect daily consumption seed on serum lipids adult subjects. Methods: work, being an interventional quasi-experimental category, involved 67 voluntary subjects (mean age: 33.51±11.40 years; 32 men; 35 women), conducted Parakou (Benin), from January...
Au regard des connaissances actuelles, aucune étude n’est disponible au Bénin sur le profil lipidique personnes vivant avec VIH. L’objectif de la présente est décrire VIH sous antirétroviral suivies CHU-O/P Porto-Novo. Il s’est agi d’une transversale, descriptive et analytique. La population d’étude a été constituée les collecte données faite à base fiche chez éligibles ayant donné leur consentement. Le apprécié par bilan réalisé patients jeun. total 244 ont inclus dans l’étude. On noté une...
Objective: Determine the prevalence and factors associated with dyslipidemia in adult subjects sickle cell disease Parakou 2017. Methods: This research work was a descriptive, analytical, cross-sectional observational study carried out from January 6 to June 6, It involved 100 (mean age: 28.77 ± 8.73 years) city of (Benin). Serum lipid parameters were measured through enzymatic colorimetric methods on Mindray ® BS-120 automaton (Guangdong, China). The different types classified according...
Background and Objective: Most chemical pesticides used in agriculture are endocrine disruptors.Several studies report the adverse effect of disruptors on male sex hormones.This study aimed to investigate profile hormones cotton growers directly exposed synthetic North-East Benin.Materials Methods: This was an observational, cross-sectional, descriptive analytical carried out from May 6 August 30, 2016 Republic Benin.Study sample consisted 95 (mean age: 33.54±9.43years) non-exposed subjects...
Introduction: Lipid profile abnormalities at birth indicate that initial genetic inheritance is already risk of developing a cardiovascular disease. Objective: Investigate the umbilical cord blood lipids term newborns in Parakou (Benin). Materials and Methods: This research work was cross-sectional study with descriptive analytical purpose, based on prospective collection data. It involved recruited through complete census three health-care facilities located city (Republic Benin), after...
<i>Background</i>: The genital infection due to Human papillomavirus (HPV) is considered as the most common sexually transmitted across world, including high-risk oncogenic HPV (HR/HPV). <i>Objective</i>: This study aimed determine prevalence of HR/HPV genotypes among active women in Parakou (Benin) 2017. <i>Methods</i>: research work was a cross-sectional descriptive carried out city (Benin), from January 15 April 15, Sample consisted 247 selected through systematic random sampling....
Genetic polymorphisms of certain classes glutathione S-transferase (GST), enzyme responsible for the biotransformation drugs and xenobiotics, have been associated with risk several cancers such as cervical cancer. The aim this study is to investigate impact M1 T1 deletion on high-risk human papillomavirus (HR-HPV) infections dysplasia. A case-control was carried out 1069 endocervical samples from West African women including 482 HR-HPV positive 139 patients had lesions according visual...
Background: Daily consumption of fruits is recommended due to their positive impact on the control glycemia, cholesterol and coronary heart disease. Objectives: This study aimed determine glycemic index load (GL) four local grown in Benin, namely papaya, pineapple, watermelon grafted mango, among apparently healthy young adult subjects. Methods: research work, being an interventional quasi-experimental category, involved 33 voluntary subjects (mean age: 23.4±1.9 years; mean body mass index:...