- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Hepatitis C virus research
- Antibiotic Resistance in Bacteria
- Liver Disease Diagnosis and Treatment
- Glutathione Transferases and Polymorphisms
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Global Cancer Incidence and Screening
- Vibrio bacteria research studies
- Malaria Research and Control
- Mosquito-borne diseases and control
- Immune Cell Function and Interaction
- Neonatal Health and Biochemistry
- Hemoglobinopathies and Related Disorders
- Genital Health and Disease
- HIV, Drug Use, Sexual Risk
- Cancer Risks and Factors
- Viral Infections and Immunology Research
- Urinary Tract Infections Management
- HIV/AIDS drug development and treatment
- COVID-19 Clinical Research Studies
- Viral Infections and Vectors
- Animal Disease Management and Epidemiology
Université Joseph Ki-Zerbo
2014-2024
University of Koudougou
2021-2024
Joseph Ayo Babalola University
2019-2023
Université Ouaga II
2017-2021
Institut Pasteur de Côte d'Ivoire
2017-2018
University of Cape Coast
2018
University of Lomé
2018
Creative Research Enterprises (United States)
2018
Institut Pasteur
2017-2018
Centre Hospitalier Universitaire de Cocody
2015
Qnr genes are known to confer a low-level resistance fluoroquinolone in Enterobacteriaceae. They often found on the same plasmids as extended spectrum β-lactamase (ESBL) and constitute most common antibiotic mechanism. This study aimed detect presence of qnr ESBL-producing E. coli Klebsiella spp. From May 2013 July 2015, 91 64 strains with phenotypic quinolone were collected from several specimens analyzed for detection qnrA, qnrB, qnrS (blaCTX-M, blaTEM, blaSHV) using simplex multiplex PCR....
The presence of HBV DNA in the liver (with detectable or undetectable serum) individuals tested HBsAg negative by currently available assays is defined occult B Infection (OBI). It remains a potential transmission threat and risk to chronic infection. purpose this study was determine OBI prevalence among subjects characterize associated genotypes.Blood samples 219 HBsAg-negative ELISA were collected. investigated all samples. Viral loads determined using quantitative real-time PCR. All...
To investigate 4 combinations of mutations responsible for glucose-6-phosphate dehydrogenase (G6PD) deficiency in a rural community Burkina Faso, malaria endemic country.Two hundred individuals were genotyped the A376G, G202A, A542T, G680T and T968C using TaqMan single nucleotide polymorphism assays polymerase chain reaction followed by restriction fragment length polymorphism.The prevalence G6PD was 9.5% study population. It significantly higher men compared to women (14.3% vs 6.0%,...
This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus (HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso.Among 131 attending Tenkodogo Urban Medical Center, endocervical samples were collected prior screening for precancerous lesions. After viral DNA extraction, fourteen HR-HPV characterized by real-time multiplex PCR these cervical samples.The mean age 35.5 ± 9.5 years. Of women, 45 infected with at least one genotype....
Studies on host factors, particularly the APOBEC3G gene, have previously found an association with AIDS progression in some populations and against HIV-1 strains but not others. Our study had two main objectives: firstly, to screen a population from Burkina Faso for three variants of described, secondly analyze effect these their haplotypes infection Circulating Recombinant Forms (CRFs) present Faso. This case control involved 708 seropositive seronegative individuals. Genotyping was done by...
African swine fever (ASF) has been endemic in sub-Saharan Africa since the 1960s. Following its introduction Senegal, 1957, ASF steadily progressed through West Africa, reaching Burkina Faso 2003, and later Mali 2016. Despite heavy burden of disease on pig production, little information is available genetic diversity virus (ASFV) Faso, Senegal. Here, we used real-time PCR ASFV to detect genome samples collected between 1989 2016, conventional approaches for isolate characterization. The...
The low rate of screening for hepatitis B virus (HBV) in pregnant women is a highrisk factor its vertical transmission. objectives this study were: i) to screen HBV infection; ii) vaccinate all children from birth against regardless their mother status; and iii) evaluate after 7 months the level AbHBs among babies who received vaccine at birth. Serological markers (HBsAg, HBeAg, AbHBs, AbHBe, AbHBc) were determined on venous blood samples 237 using Abon Biopharm Kit. One hundred two (102)...
Epstein Barr Virus (EBV) and Human Herpes 6 (HHV-6) are responsible for severe diseases, particularly in immunocompromised persons. There is limited data of the infection these opportunistic viruses Burkina Faso. The purpose this study was to characterize EBV HHV-6 subtypes assess their impact on CD4 T cell count, HIV-1 viral load antiretroviral treatment people living with HIV-1. population consisted 238 HIV-positive patients information HAART. Venous blood samples collected EDTA tubes were...
Introduction: breast cancer is a common cause of death among women in Burkina Faso. The aim this study was to determine descriptive profile 80 and establish description risk factors associated with these women.
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G (APOBEC3G) is a potent host defense factor, which interferes with HIV-1 and HBV. Our study had three objectives, to screen population of infected uninfected patients in Burkina Faso for HBV, the APOBEC3G variants rs6001417, rs8177832, rs35228531 previously described, analyze effect these their haplotypes on HIV-1/HBV co-infection Faso.HBV detection was performed samples from subjects using rapid tests real-time PCR. APOBEC3...
Abstract Objectives A cluster of specialized KIR genes has been shown to be associated with susceptibility or resistance viral infections in humans. Therefore, this pilot study, investigation sought determine the frequencies human immunodeficiency virus type 1( HIV-1) patients and establish their potential clinical involvement disease progression staging. Methods HIV-1 infected healthy individuals were selected for study. Hepatitis B surface antigen (HBsAg), anti-HCV antibodies anti-HIV-1/2...
Background and ObjectiveThe improved performance of serological tests has significantly reduced the risk human immunodeficiency hepatitis B C viruses transmission by blood transfusion, but there is a persistence residual risk. The objective this study was to evaluate impact multiplex PCR in reducing these seronegative donors Burkina Faso.MethodsThis cross-sectional conducted from March September 2017. were performed on sera using ARCHITECTSR i1000 (Abbot diagnosis, USA). Detection viral...
The G-6-PD deficiency has an important polymorphism with genotypic variants such as 202A/376G, 376G/542T and 376G/968T known in West African populations. It would confer protection against severe forms of malaria although there are differences between the various associations different studies. In this study we genotyped six (06) gene people symptomatic urban areas Burkina Faso. One hundred eighty-two (182) patients who tested positive using rapid detection test microscopy were included...
Hepatitis B virus (HBV) genotype E (HBV‐E) accounts for the majority of chronic hepatitis (CHB) infections in West Africa. We aimed to determine factors associated with HBV‐E‐induced hepatocellular carcinoma (HCC) Data on patients from Burkina Faso who were surface antigen positive (HBsAg+) and had CHB analyzed. HBV viral load e (HBeAg) status measured 3,885 individuals without HCC (CHB HCC−) 59 HCC+). genotyping was performed 364 subjects HCC− 41 HCC+. Overall, 2.5% group HBeAg+ compared 0%...
Hepatitis B virus (HBV) infection is the leading risk factor for cirrhosis and hepatocellular carcinoma (HCC). The objective of this investigation was to assess association between "Killer Cell Immunoglobulin-Like Receptor" (KIR) gene frequencies chronic HBV infection.Chronic carriers healthy patients were selected study. viral load performed, SSP-PCR used characterize KIR genes.The study suggested that inhibitory genes KIR2DL2 (crude OR = 2.82; p < 0.001), KIR2DL3 2.49; 0.001) activator...