Ge Luo

ORCID: 0000-0001-6681-9308
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About
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Research Areas
  • Herpesvirus Infections and Treatments
  • Spine and Intervertebral Disc Pathology
  • Pain Mechanisms and Treatments
  • Healthcare and Venom Research
  • Nerve Injury and Rehabilitation
  • Sympathectomy and Hyperhidrosis Treatments
  • Anesthesia and Pain Management
  • Trigeminal Neuralgia and Treatments
  • Genomics, phytochemicals, and oxidative stress
  • Pain Management and Opioid Use
  • Shoulder Injury and Treatment
  • Migraine and Headache Studies
  • Peripheral Nerve Disorders
  • Pain Management and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Botulinum Toxin and Related Neurological Disorders
  • Spinal Hematomas and Complications
  • Cardiac Valve Diseases and Treatments
  • Nausea and vomiting management
  • Bone Metabolism and Diseases
  • Research on Leishmaniasis Studies
  • Thyroid and Parathyroid Surgery
  • Developmental Biology and Gene Regulation
  • Biochemical effects in animals
  • Infrared Thermography in Medicine

Sichuan Normal University
2025

Zhejiang University
2025

Second Affiliated Hospital of Zhejiang University
2024

Bengbu Medical College
2021-2023

Jiaxing University
2021-2023

First Hospital of Jiaxing
2020-2022

Background: The burden of migraine is increasing and has become the leading neurological cause disability among children adolescents aged 5-19. We aim to provide updated epidemiological evidence on incidence, prevalence disability-adjusted life years (DALYs) adolescents.

10.2139/ssrn.5083853 preprint EN 2025-01-01

Observational fear learning delineates the process by which individuals learn about potential threats through observing others' reactions. Prior research indicates that with high trait anxiety (HTA) manifest pronounced responses in direct scenarios. However, specific influence of on observational remains insufficiently explored. This study aimed to fill this gap examining 64 university students, divided equally between those HTA and low (LTA), selected from an initial pool 483 participants....

10.1016/j.neuroimage.2025.121037 article EN cc-by-nc-nd NeuroImage 2025-01-17

Bone cancer pain (BCP) is a pervasive clinical symptom which impairs the quality life. Long noncoding RNAs (lncRNAs) are enriched in central nervous system and play indispensable roles numerous biological processes, while its regulatory function nociceptive information processing remains elusive. Here, we reported that functional modulatory role of ENSRNOT00000071132 (lncRNA71132) BCP process sponging with miR-143 downstream GPR85-dependent signaling cascade. Spinal lncRNA71132 was...

10.1097/j.pain.0000000000002678 article EN Pain 2022-05-11

Bone cancer pain (BCP) is a clinical pathology that urgently needs to be solved, but research on the mechanism of BCP has so far achieved limited success. Nuclear factor erythroid 2 (NFE2)-related (Nrf2) been shown involved in pain, its involvement and specific have yet examined. This study aimed test hypothesis induces transfer Nrf2 from cytoplasm nucleus further promotes nuclear transcription activate heme oxygenase-1 (HO-1) inhibit activation factor-kappa B (NF-κB) signalling, ultimately...

10.1111/jnc.15468 article EN cc-by-nc-nd Journal of Neurochemistry 2021-07-13

Bone cancer pain (BCP) is a serious clinical problem that affects the quality of life patients. However, current treatment methods for this condition are still unsatisfactory. This study investigated whether intrathecal injection rosiglitazone modulates noxious behaviors associated with BCP, and possible mechanisms related to effect were explored. We found relieved bone cancer-induced mechanical hyperalgesia in dose-dependent manner, promoted expression peroxisome proliferator-activated...

10.1155/2021/6086265 article EN cc-by PPAR Research 2021-08-25

Primary trigeminal neuralgia can achieve satisfactory results through clinical treatment and intervention. The pathogenesis of caused by varicella-zoster virus infection the nerve is more complex, it still difficult to relieve pain in some patients simply drug or surgical intervention.A 66-year-old woman was hospitalized with herpetic after herpes zoster ophthalmicus (varicella-zoster infects ophthalmic branch nerve). On admission, patient showed spontaneous, electric shock-like...

10.12998/wjcc.v10.i13.4220 article EN World Journal of Clinical Cases 2022-04-29

Different views have been proposed on the radiofrequency treatment modes and parameters of thermocoagulation spinal dorsal root ganglion for postherpetic neuralgia (PHN). It is urgent to identify a more effective therapy patients with PHN.Patients who underwent PHN were retrospectively reviewed divided into (CRF) double neddles (DCRF). The pain scores (numerical rating scale, NRS) evaluated at following time points: before operation, 1 day, 3 months, 6 year, 2 years after operation....

10.3344/kjp.2022.35.1.114 article EN cc-by-nc The Korean journal of pain 2021-12-30

Although video-assisted thoracoscopy has a smaller incision than traditional surgery, the postoperative pain is still severe. Ultrasound-guided pectoral nerve block (PECS) II new technique that can reduce in patients, and it had not been reported analgesia after thoracoscopic lobectomy.40 patients scheduled for lobectomy were randomly divided into two groups. Patients PECS group received 0.5% ropivacaine 25 ml before general anesthesia, while placebo 0.9% saline. Thirty minutes was...

10.1155/2021/6693221 article EN cc-by BioMed Research International 2021-04-16

To analyze the influencing factors of motor dysfunction in patients with limb herpes zoster and to construct a nomogram predict risk this complication.A total 213 First Hospital Jiaxing from January 2015 June 2020 were enrolled. The muscle strength affected was evaluated by Medical Research Council (MRC) score. less than grade 5, lower that contralateral (normal side) defined as dysfunction. Univariate multivariate logistic regression analyses used determine zoster. drawn R software....

10.2147/jpr.s346564 article EN cc-by-nc Journal of Pain Research 2022-02-01

Postherpetic neuralgia (PHN) is a painful condition that persists for 1 month or more after herpes zoster rash has healed. Radiofrequency thermocoagulation (RF-TC) provides analgesia by destroying the dorsal root ganglion and blocking pain upload pathway; nonetheless, concomitant neurological-related side effects recurrence remain concern.In this study, 228 patients with PHN in thoracic segment treated RF-TC of spinal nerve were included, followed up regularly surgery. The numerical rating...

10.1007/s40122-022-00412-x article EN cc-by-nc Pain and Therapy 2022-07-02

Abstract Notch signal plays an important role in regulating cell–cell interactions with the adjacent cells. However, it remains unknown whether Jagged1 (JAG‐1) mediated signaling regulates bone cancer pain (BCP) via spinal cell mechanism. Here, we showed that intramedullary injection of Walker 256 breast cells increased expression JAG‐1 astrocytes and knockdown reduced BCP. The supplementation exogenous to cord induced BCP‐like behavior promoted c‐Fos hairy enhancer split homolog‐1 (Hes‐1)...

10.1111/jnc.15910 article EN Journal of Neurochemistry 2023-07-08

Postinduction hypotension (PIH), occurring between anaesthesia induction and surgical incision, is particularly concerning in older adults undergoing transcatheter aortic valve replacement (TAVR) due to their multiple comorbidities age-related cardiovascular changes. This study aimed assess the relationship PIH postoperative adverse events TAVR patients.

10.2147/cia.s487629 article EN cc-by-nc Clinical Interventions in Aging 2024-11-01

The purpose of this study was to evaluate the effectiveness and safety computed tomography (CT)-guided radiofrequency thermocoagulation (RFTA) sphenopalatine ganglion (SPG) for patients with refractory headache. A total 14 migraine 10 cluster headache (CH) who underwent CT-guided SPG RF between May 2019 August 2021 at Jiaxing First Hospital, located in City, Zhejiang Province, China, were included analyzed retrospective cohort study. Pain score, sleep quality scores, treatment effects...

10.1007/s40122-022-00401-0 article EN cc-by-nc Pain and Therapy 2022-07-06

Objective: To investigate the efficacy and safety of CT-guided radiofrequency ablation posterior root spinal nerve in treatment postherpetic neuralgia (PHN). Methods: A total 102 PHN patients (42 males 60 females) aged (69.7±9.4) years who underwent Department Pain Medicine Affiliated Hospital Jiaxing University from January 2017 to April 2020 were retrospectively included. Patients followed up, numerical rating scale (NRS) score, Pittsburgh sleep quality index (PSQI), satisfaction score...

10.3760/cma.j.cn112137-20220519-01105 article EN PubMed 2023-02-21
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