A5042019870- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Bacterial biofilms and quorum sensing
- Bee Products Chemical Analysis
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Natural Antidiabetic Agents Studies
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Psidium guajava Extracts and Applications
- Microbial Metabolism and Applications
- African Botany and Ecology Studies
- Bioactive natural compounds
- Traditional and Medicinal Uses of Annonaceae
- Plant-based Medicinal Research
- Piperaceae Chemical and Biological Studies
- Chemical synthesis and alkaloids
- Insect and Pesticide Research
- Plant biochemistry and biosynthesis
- Pharmacological Effects of Natural Compounds
- Moringa oleifera research and applications
- Natural Compound Pharmacology Studies
- Oral microbiology and periodontitis research
- Antimicrobial agents and applications
- Antibiotic Resistance in Bacteria
Muğla University
2019-2025
University of Ngaoundéré
2020-2025
Usak University
2023-2025
"Dunarea de Jos" University of Galati
2020-2024
University of Karachi
2019-2022
International Center for Chemical and Biological Sciences
2019-2022
Université de Yaoundé I
2016-2019
Recently, the honey and propolis of stingless bees have been attracting growing attention because their health-promoting properties. However, studies on these products African Meliponini are still very scarce. In this preliminary study, we analyzed chemical composition honey, two cerumen, resin deposits (propolis) samples Meliponula ferruginea from Tanzania. The M. was profiled by NMR indicated different long-term stability Apis mellifera European (Bulgarian) honey. It differed significantly...
Abstract In recent years, there have been an attempt to develop safe and environmental friendly solvents replace conventional solvents, use for extraction bioactive compounds from natural sources. A current investigation involved the preparation of green, methanolic, ultrasonic extracts S. sclarea , compared their phenolic profiling using HPLC–DAD, antibacterial, antioxidant, enzyme inhibition activities. The HPLC–DAD analysis revealed that Rosmarinic acid was main content in all extracts,...
Propolis is very popular for its beneficial health properties, such as antimicrobial activity and antioxidant effects. It one of the most long-serving traditional medicines to mankind due interesting chemical diversity therapeutic properties. The detailed information propolis samples necessary guarantee safety it be accepted into care systems. phenolic profile hydroethanolic extract was determined using HPLC-DAD, evaluated five complementary methods. Triterpenoids were isolated column...
Gum arabica is a local commercial nutraceutical and food preservative collected mostly from acacia plants. HPLC-DAD analysis identified gallic acid, syringic ferulic coumarin, rutin rosmarinic acid in hydroethanol extracts of all three species with being the most abundant component Acacia ataxacantha (45.25 ± 0.33 mg/g) sieberiana (130.3 0.65 nilotica (125.50 0.51 mg/g). Extracts displayed good antioxidant capacities β-carotene-linoleic DPPH•, ABTS•+, CUPRAC metal chelating assays were more...
Phenolic extracts of
Alzheimer’s disease (AD) and diabetes are non-communicable diseases with global impacts. Inhibitors of acetylcholinesterase (AChE) butyrylcholinesterase (BChE) suitable therapies for AD, while α-amylase α-glucosidase inhibitors employed as antidiabetic agents. Compounds were isolated from the medicinal plant Terminalia macroptera evaluated their AChE, BChE, α-amylase, inhibitions. From 1H 13C NMR data, compounds identified 3,3′-di-O-methyl ellagic acid (1), 3,3′,4′-tri-O-methyl...
The extracts of some propolis samples were analysed by GC-MS and then purified column chromatography. latter led to the isolation a new mono-ether glycerol, 1'-O-eicosanyl glycerol triterpene, methyl-3β,27-dihydroxycycloart-24-en-26-oate together with known triterpenoids namely betulin, 3β-hydroxylanostan-9,24-dien-21-oic acid, mangiferonic mixture ambolic acid β-sitosterol, 3β-hydroxycycloartan-12,24(25)-diene 27-hydroxymangiferonic acid. DPPH radical scavenging potential compounds...
Food pathogens represent an important health threat, and it is relevant to study the effect of foodstuffs such as spices which can inhibit bacterial growth. This reports antimicrobial, antibiofilm, enzyme (Acetylcholinesterase, Butyrylcholinesterase, urease, tyrosinase) inhibitory activities two medicinal food belonging Annonaceae family, Monodora myristica Xylopia aethiopica. GC-MS (gas chromatography mass spectrometry) analysis silylated samples Methanol-Dicloromethane (50:50) extracts...
Diabetes as well the enhanced microbial multidrug resistance resulting from biofilm formation, constitutes some of major health problems around world. Triterpenoids and their derivatives have been shown to a great contribution in this domain. A small library benzoyl esters lupeol β-amyrin was synthesized structures were characterized by electronic ionization mass spectrometry (EIMS). Their inhibitory potential on pathogenic bacteria biofilms, action α-amylase β-glucosidase activities...
Diabetes mellitus is a metabolic disorder which one of the leading causes mortality and morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb amputation, heart attack stroke. Physical activity, healthy diets medications reduce incidence diabetes, so search for more efficient antidiabetic therapies, most especially from natural products, necessity. Herein, extract roots medicinal plant Pterocarpus erinaceus was purified by column chromatography afforded...
Microbial infections cause serious health problems especially with the rising antibiotic resistance which accounts for about 700,000 human deaths annually. Antibiotics target bacterial death encounter microbial time, hence, there is an urgent need search of antimicrobial substances disruption virulence factors such as biofilm and quorum sensing (QS) selective pressure on pathogens so to avoid resistance.Natural products are suitable leads drugs that can inhibit biofilms QS. Twenty compounds...
Objective Lamiaceae plants have high aromatic and medicinal qualities. This work reports the chemical composition of essential oils (EOs) from Thymus capitatus, T. fontanesii Lavandula stoechas together with their inhibitory effects selected enzymes microbial virulence factors. Methods EOs were obtained by hydrodistillation compositions determined GC-FID/GC-MS. The enzyme inhibition on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, urease tyrosinase...
ABSTRACT Insufficiency of energy resources affects the economy and constitutes a global crisis. Solar represents an immense renewable source, various photovoltaic cells, such as polymer solar are being developed to tap make it available for consumption. This work describes synthesized anthracene‐conjugated polymers with alkoxyl side‐chain distributions via Horner–Wadsworth–Emmons polyolefination reactions. Nuclear magnetic resonance (NMR), size exclusion chromatography (SEC), x‐ray...
ABSTRACT Macrocyclic calix[ n ]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p ‐ tert ‐butylcalix[4]arene conjugates ( AT10a AT10b ) their ‐butylphenol analogs AT11b were synthesized in good yields characterized using 13 C NMR 1 H experiments. The compounds evaluated for antimicrobial (AM) activity against Gram‐positive...
This study introduces Centaurea napifolia as a novel multifunctional corrosion inhibitor and zinc-electroplating additive previously unexplored in the field. Hydro-methanolic, methylene dichloride, ethyl acetate, n-butanol extracts were investigated for their dual functionality: inhibiting of carbon steel improving performance zinc electrodeposition on mild steel. Using techniques such potentiodynamic polarization, gravimetric methods, electrochemical impedance spectroscopy, scanning...
Medicinal plants from Chad grow under special climatic conditions in between the equatorial forest of Central Africa and desert North are understudied. Three medicinal (T. diversifolia, P. Biglobosa C. Febrifuga) were evaluated for their phenolic composition, antioxidant enzyme inhibition activities. The total composition varied 203.19 ± 0.58 mg GAE/g DW ethyl acetate extract biglobosa, to 56.41 0.89 methanol febrifuga while flavonoid content 51.85 0.91 QE/g biglobosa 08.56 0.25 febrifuga....
Abstract. Arab Y, Sahin B, Ceylan O, Zellagui A, Olmez OT, Kucukaydin S, Tamfu AN, Ozturk M, Gherraf N. 2022. Assessment of in vitro activities and chemical profiling Senecio hoggariensis growing Algerian Sahara. Biodiversitas 23: 3498-3506. The antioxidant, anticholinesterase, tyrosinase inhibitory, antibiofilm, anti-quorum sensing the ethyl acetate extract hoggariensis,growing Sahara, were studied along with its constituents using HPLC-DAD. chromatographic analysisunveiled seven phenolic...