A5049125470- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Viral gastroenteritis research and epidemiology
- Ultrasound and Hyperthermia Applications
- Bee Products Chemical Analysis
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- Dermatology and Skin Diseases
- Microbial Inactivation Methods
- RNA Interference and Gene Delivery
- Lipid Membrane Structure and Behavior
- HIV/AIDS drug development and treatment
- Essential Oils and Antimicrobial Activity
- Dietary Effects on Health
- Dermatologic Treatments and Research
- Skin Protection and Aging
- Inhalation and Respiratory Drug Delivery
- Textile materials and evaluations
- Gastrointestinal Bleeding Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Microscopic Colitis
- Spectroscopy Techniques in Biomedical and Chemical Research
- Optical Coherence Tomography Applications
- Biochemical and Molecular Research
- Gastrointestinal disorders and treatments
Massachusetts Institute of Technology
2012-2020
Koch Institute for Integrative Cancer Research At MIT
2015
United States Military Academy
2011
Ultrasound enables rapid and local delivery of drugs to the gastrointestinal tract for treatment inflammatory diseases, such as ulcerative colitis.
Wireless capsule endoscopy (WCE) has revolutionized the capacity for evaluation of gastrointestinal (GI) tract. Although WCE provides high quality images GI tract, is limited to mucosal surface. This work investigates feasibility and design considerations wireless endoscopic ultrasound (WCEU) that combines benefits imaging. two goals: (1) evaluate transducer designs appropriate WCEU (2) investigate whether peristalsis can produce sufficient contact ensure acoustic coupling. Between...
Rapid and effective drug delivery to the gastrointestinal (GI) tract can be a significant challenge. This is because of harsh environment present in GI fast transit times disease states. Physical enhancers, such as ultrasound (US), may enable rapid therapeutics while circumventing need for formulation development. Despite being investigated other uses, low frequency US has not been studied GI-based previously. Our group developed hand-held device colonic mucosa. The utilizes low-frequency...
Die Kluft zwischen Wirkstoffentwicklung und der erfolgreichen Umsetzung in die klinische Praxis (Translation) ist gewaltig. Wirksame Lösungen erfordern Zusammenarbeit multidisziplinärer Teams von unterschiedlicher Expertise (Konvergenz). Dieser Essay stellt zwei Fallbeispiele für Entwicklung dauerhafter Wirkstoffverabreichungssysteme Antimalaria- antiretrovirale Medikamente im Magen-Darm-Trakt vor.