A5021140746- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- Black Holes and Theoretical Physics
- Reconstructive Surgery and Microvascular Techniques
- Neutrino Physics Research
- High-Energy Particle Collisions Research
- Wound Healing and Treatments
- Nonlinear Waves and Solitons
- Atrial Fibrillation Management and Outcomes
- Quantum, superfluid, helium dynamics
- Dermatologic Treatments and Research
- Pressure Ulcer Prevention and Management
- Atomic and Subatomic Physics Research
- Orthopedic Surgery and Rehabilitation
- Cosmology and Gravitation Theories
- Advanced NMR Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Superconducting Materials and Applications
- Cold Atom Physics and Bose-Einstein Condensates
- Reconstructive Facial Surgery Techniques
- Physics of Superconductivity and Magnetism
- Nonlinear Photonic Systems
- Computational Physics and Python Applications
- Antibiotics Pharmacokinetics and Efficacy
- Head and Neck Cancer Studies
Showa University
2003-2024
Nagasaki University Hospital
2019-2024
Nagasaki University
2011-2023
Showa University Koto Toyosu Hospital
2020-2023
Showa University Hospital
2008-2023
Koto Hospital
2020-2023
Yokohama Sakae Kyosai Hospital
2018
Osaka University of Pharmaceutical Sciences
1987-2016
Lake Biwa Museum
2009-2011
Tokyo Metropolitan Komagome Hospital
2010
Cisplatin (cis-diamminedichloroplatinum II), an anticancer chemotherapeutic agent with the dose-limiting side effect of nephrotoxicity, caused a statistically significant increase in lipid peroxidation, monitored by measuring production malondialdehyde, rat kidney 72 hr after injection. Treatment rats beforehand antioxidant α-tocopherol or N-N′-diphenyl-p-phenyl-enediamme (DPPD) effectively decreased such peroxidation. DPPD was more effective inhibitor than α-tocopherol, since it is known...
The forkhead box O (FOXO) family has been extensively investigated in aging and metabolism, but its role tissue-repair processes remains largely unknown. Herein, we clarify the molecular aspect of FOXO skin wound healing. We demonstrated that Foxo1 Foxo3a were both up-regulated during murine Partial knockout Foxo1(+/-) mice throughout body led to accelerated healing with enhanced keratinocyte migration, reduced granulation tissue formation, decreased collagen density, accompanied by an...
Research Article31 August 2018Open Access Source DataTransparent process Targeting miR-223 in neutrophils enhances the clearance of Staphylococcus aureus infected wounds Maiko de Kerckhove Department Pathology, Nagasaki University School Medicine and Graduate Biomedical Sciences, Nagasaki, Japan Search for more papers by this author Katsuya Tanaka Plastic Reconstructive Surgery, Ehime Prefectural Center Hospital, Ehime, Takahiro Umehara Forensic Pathology Science, Momoko Okamoto Immunology...
The operators and commutators of the space-time coordinates momenta in quantized are formulated. Then eigenfunctions eigenvalues found. Finally, time spectrum plane-wave solution Dirac equation is determined a convergent perturbation analysis proposed.
Pediatric burn wounds can be problematic because an accurate evaluation is difficult as the result of anatomically immature vasculature or immobilization failure, especially in patients with second-degree burns, and surface areas depth tend to worsen over course time. Delayed wound healing results unsightly scarring, such hypertrophic scars, which are both esthetically functionally. Among cytokines growth factors, basic fibroblast factor (bFGF) clinically proven, having demonstrated...
Various methods have been attempted for the treatment and management of keloids; however, there is little satisfactory clinical evidence in long-term follow ups. Also, a preference occurrence recurrence anatomic location. Usually locations with higher regional tension more sebaceous glands are inclined toward pathogenesis. Thirty-eight keloids treated combined surgical excision postoperative irradiation, using electron beams only 10-mm opening by lead shielding, were investigated at mean up...
307 probands with febrile convulsions classed as the simple type (131 children) and complicated (176 were genetically analyzed. There was a tendency toward familial aggregation of convulsions, genetic involvement suggested. The multifactorial mode inheritance best agreed observations. (1) ratio incidence in siblings present study (19.9%) to general population (2.9%), i.e., 6.85, rather close expected 5.87 from system. (2) tended be higher when either or both their parents had history...
Background: There is currently no reliable treatment for secondary lymphedema caused by lymph node dissection or radiotherapy; however, stem cell–based regenerative medicine emerging as a promising remedy such complications. The purpose of this study was to examine the effects adipose-derived cells on lymphangiogenesis involving human dermal lymphatic endothelial exposed ionizing radiation. Methods: Proliferation, migration, and tube formation were analyzed in that co-cultured with cultured...
Background: Although a number of cytokine or growth factor therapies for wound acceleration have been reported, few mentioned the quality outcome. The lower extremity is important in esthetics as well function, because it exposed. Recently, factor, namely basic (bFGF) widely used difficult healing with porcine-derived bilayered artificial dermis better closure. Thus, their combination use was tested clinically. Methods: Sequential reconstruction by an without bFGF administration and...
We introduce a modified SO(3) model of weak- and electromagnetic-interaction symmetry. The is renormalizable reproduces the usual theory weak interactions. Four additional heavy leptons five quarks are necessary. electromagnetic charge radius neutrino calculated in $\ensuremath{\xi}$-limiting procedure finite result found.
\ifmmode \check{C}\else \v{C}\fi{}erenkov radiation is investigated for the following cases: charged particles and neutrons moving in isotropic crystals; an arbitrary direction with respect to optic axis uniaxial crystals.
Background: Distraction osteogenesis has some advantages, such as less hazardous complications, scarring, and fewer bone defects. However, it not been fully accepted yet because of a unidirectional expansion along the distraction device. Because cranial is limited by scalp tension soft-tissue undercorrection cranium relapse vault deformities have occasionally seen on long-term follow-up. These patients also had so much defect that donor was inadequate for immediate revisions, dissection...
The prevalence of pressure injuries is an essential indicator prevention and quality care. Population-based data on are scarce in Japan. This study aimed to estimate the per 1000 adults older people Japan.Cross-sectional survey.This was conducted Goto, a city located remote rural archipelago In 2017, population 37,855; aged ≥65 years accounted for 37.7%.Participants were enrolled various facilities city. total, 1126 participants (median age 85 years) assessed calculate age-specific numbers...
Xeroderma pigmentosum (XP) is a genodermatosis defined by cutaneous photosensitivity with an increased risk of skin tumors because DNA repair deficiency. The worldwide prevalence XP ~1 to 4 in million, higher incidence some countries and regions including Japan (1 22,000) North Africa due founder mutations high degree consanguinity. Among XP, the complementation group F (XP-F), rare form (1% XP); however, this underdiagnosed, ERCC4 / XPF gene essential for fetal development most previously...
Color changes of visible and exposed body surfaces, such as the face extremities, after burn injury or surgery, skin grafting, flap, sclerotherapy for vascular malformations, are sometimes a concern. The consequences reduce satisfaction both patients physicians. An easy reproducible method has not yet been established an objective analysis color changes; therefore, we tested hand-held analyzer (NF-333; Nippon Denshoku Co. Ltd) with data transport to computer database software posttreatment...
The Japanese Society for Burn Injuries (JSBI) published the third edition of guidelines to present standard care inpatient treatment burn injuries in Japan. guideline is not a mere revision first and second editions but has been carefully designed be user friendly high quality medical professionals engaged care. We think it important share these with other countries work toward consensus care, then develop new research establish evidence future.
The $\ensuremath{\Delta}Q=0$, $\ensuremath{\Delta}S=1$ component of the unitary spin current is used in interactions that are both weak and electromagnetic. effective coupling constant determined from experimental decay rate ${\ensuremath{\Sigma}}^{+}\ensuremath{\rightarrow}p+\ensuremath{\gamma}$. With aid symmetry arguments, rare rates modes $B\ensuremath{\rightarrow}{B}^{\ensuremath{'}}+\ensuremath{\gamma}$, $B\ensuremath{\rightarrow}{B}^{\ensuremath{'}}+{e}^{+}+{e}^{\ensuremath{-}}$,...