Ana C. Almeida-Santos

ORCID: 0000-0001-6711-4780
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About
Contact & Profiles
Research Areas
  • Antimicrobial Resistance in Staphylococcus
  • Probiotics and Fermented Foods
  • Bacterial Identification and Susceptibility Testing
  • Oral microbiology and periodontitis research
  • Oral Health Pathology and Treatment
  • Clostridium difficile and Clostridium perfringens research
  • Infective Endocarditis Diagnosis and Management
  • Mycobacterium research and diagnosis
  • Genomics and Phylogenetic Studies
  • Gut microbiota and health
  • HIV/AIDS oral health manifestations
  • Microbial Natural Products and Biosynthesis
  • Antibiotic Resistance in Bacteria
  • Milk Quality and Mastitis in Dairy Cows
  • Salivary Gland Disorders and Functions
  • Bacterial biofilms and quorum sensing

Universidade do Porto
2020-2025

Instituto de Saúde
2024

Rede de Química e Tecnologia
2021-2022

Centro de Investigação em Biodiversidade e Recursos Genéticos
2020

ABSTRACT Multidrug-resistant Enterococcus faecium strains represent a major concern due to their ability thrive in diverse environments and cause life-threatening infections. While antimicrobial resistance virulence mechanisms have been extensively studied, the contribution of bacteriocins E. ’s adaptability remains poorly explored. , within Bacillota phylum, is prominent bacteriocin producer. Here, we developed tailored database 76 (217 sequences, including 40 novel bacteriocins) applied it...

10.1128/aem.01376-24 article EN Applied and Environmental Microbiology 2024-09-16

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that becoming significant global health care problem. Several studies have shown people with are more susceptible to oral problems, such as periodontitis and, although the causes still inconclusive, microbiota considered play major role in health. This study aimed characterize microbiome of sample representing T2DM patients from Portugal and exploit potential associations between some microorganisms variables like teeth brushing,...

10.3389/fmicb.2021.610370 article EN cc-by Frontiers in Microbiology 2021-02-05

Enterococcus faecium is a WHO priority pathogen that causes severe and hard-to-treat human infections. It was recently proposed E. colonizing the gut (previous clade B) actually corresponds to lactis ; therefore, some of infections occurring globally are being misidentified.

10.1128/spectrum.03268-22 article EN cc-by Microbiology Spectrum 2022-12-01

Multidrug-resistant (MDR) Enterococcus faecium (Efm) infections continue to increase worldwide, although epidemiological studies remain scarce in lower middle-income countries. We aimed explore which strains circulate E. causing human Tunisian healthcare institutions order compare them with from non-human sources of the same country and finally position within global epidemiology by genomic analysis. Antibiotic susceptibility testing was performed transfer vancomycin-vanA ampicillin-pbp5...

10.3390/microorganisms10030632 article EN cc-by Microorganisms 2022-03-16

Enterococcus spp. are opportunistic human pathogens colonizing the gut and a significant reservoir for continuous adaptation of hospital clones. However, studies on features enterococci species co-colonizing healthy individuals scarce. We investigated prevalence, antibiotic resistance, bacteriocin profiles in fecal samples from adults Portugal using culture-based methods, WGS, inhibition assays. Results were compared with data 2001 study same region. (n = 315; 24% MDR) recovered all...

10.1128/aem.01699-24 article EN cc-by Applied and Environmental Microbiology 2024-12-19

ABSTRACT Multidrug-resistant Enterococcus faecium represent a major concern due to their ability thrive in diverse environments and cause life-threatening infections. While antimicrobial resistance virulence mechanisms have been extensively studied, the contribution of bacteriocins E. ’s adaptability remains poorly explored. , within Bacillota phylum, is prominent bacteriocin producer. Here, we developed tailored database 76 (217 sequences, including 40 novel bacteriocins) applied it uncover...

10.1101/2023.11.13.566347 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-11-13

Introduction: Forensic Microbiology is an emerging discipline in clinical diagnostics and public health that can be applied, for example, to clarify the origin of a hospital-acquired infection [1].Enterococcus faecium (Efm) colonizes human gut but also one leading hospital pathogen worldwide.Last year, taxonomic restructuration proposed Efm inhabiting may actually correspond Enterococcus lactis species, while those causing infections are truly [2].Objectives: Our main goal was assess current...

10.51126/revsalus.v4isup.355 article EN cc-by RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia 2022-04-06

Abstract Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that becoming significant global health care problem. Several studies have shown people with are more susceptible to oral problems, such as periodontitis and, although the causes still inconclusive, microbiota seems be an important factor in this interaction. This study aimed characterize microbiome of sample representing T2DM patients from Portugal and exploit potential associations between some microorganisms variables...

10.1101/2020.04.07.031070 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-04-10
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