In Brief Purpose: To subsegment the choroid in patients with polypoidal choroidal vasculopathy and to determine whether ratio of choriocapillaris/Sattler layer thickness total is decreased at sites pathology. Methods: Retrospective, observational, cross-sectional study. A 320 eyes 305 were studied optical coherence tomography dye angiography. The was calculated lesion subfoveal (SFCT) ≤200 μm. Results: Mean SFCT 267.7 ± 118.5 μm for entire cohort. 151.2 35.0 (n = 124, 39%). this subgroup,...

To study the repeatability and reproducibility of tear meniscus height (TMH) measurements obtained with a keratograph Fourier domain optical coherence tomography (FD-OCT) to assess their agreement in patients dry eye.Sixty-four eyes eye were analyzed by Schirmer test, breakup time fluorescein corneal staining. The TMH was measured 3 times using both devices 2 different examiners. assessed within-subject standard deviation (Sw), (2.77 Sw), coefficient variation (CoV), intraclass correlation...

Abstract To analyze features of the choriocapillaris in eyes with earlier stages pachychoroid spectrum, this study included 46 PPE, 32 age-matched without epitheliopathy, and 30 normal controls. Macular 3 × mm 2 angiographic images were obtained swept-source optical coherence tomography. Vascular density signal void area analyzed. Topographical correlation voids dilated choroidal large vessel (pachyvessel) was assessed. Choriocapillaris vascular significantly lower PPE compared controls ( p...

This retrospective study was to compare the efficacy of intravitreal injection ranibizumab and aflibercept for patients with pachychoroid neovasculopathy. 54 eyes were initially treated 3 monthly loading injections or aflibercept. Treatment switching from aflibercept, photodynamic therapy done at months in case incomplete fluid absorption. At months, rate complete absorption significantly higher aflibercept-treated group than ranibizumab-treated (82.6% vs 51.6%, p = 0.018). The mean...

Aims Automatic identification of pachychoroid maybe used as an adjunctive method to confirm the condition and be help in treatment for macular diseases. This study investigated feasibility classifying disease on ultra-widefield indocyanine green angiography (UWF ICGA) images using automated machine-learning platform. Methods Two models were trained with a set including 783 UWF ICGA patients (n=376) non-pachychoroid (n=349) diseases AutoML Vision (Google). Pachychoroid was confirmed...

To reveal choroidal morphological profiles under pachydrusen.Drusen in pachychoroid disorders show certain differences from conventional drusen and are recently named as "pachydrusen." This study analysed the specific morphology pachydrusen.This is a cross-sectional case series.Enrolled were 136 eyes with pachydrusen 134 patients.The presence of fundus area covered by 12 × 9 mm2 optical coherence tomography (OCT) image was accessed pachychoroid-related diseases or their fellow using colour...

Purpose: To investigate the association between geographic atrophy (GA) and neovascular activity in retinal angiomatous proliferation (RAP) during anti-VEGF treatment. Methods: Ninety-one RAP eyes (74 patients) treated with on an as-needed basis for at least 3 years were evaluated. Development of GA, area injection numbers assessed. Results: Eighteen that developed fibrous scar or massive hemorrhage excluded. Forty-four (60%) GA (GA group), 29 (40%) did not develop (non-GA group) year 3. The...

Purpose: To evaluate the effectiveness of 3% diquafosol tetrasodium for treating dry eye after cataract surgery.Methods: Among patients who underwent bilateral surgery, 34, met diagnostic criteria syndrome 1 week postoperatively, were enrolled. Patients randomly assigned to receive 3.0% ophthalmic solution in one and 0.9% saline other four times daily 8 weeks. Dry severity was measured at 1, 5, 9 postoperative weeks using Schirmer test (SIT), tear film breakup time (TBUT), fluorescein...

Abstract This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow and eyes children with unilateral hyperopic amblyopia. Sixty-four of 32 childeren anisometropic amblyopia 38 19 healthy (controls), aged 3 16 years. Subfoveal thickness (CT) CV were measured using spectral domain optical coherence tomography. The mean subfoveal CT (338.9 ± 60.0 μm) greater than that (315.3 63.3 μm, P = 0.043) (313.0 42.1 0.025). (0.715 0.020) (0.700...

To analyze the differences in vitreous cytokine profiles epiretinal membrane eyes with and without an ectopic inner foveal layer (EIFL).Sixty (32 EIFL 28 EIFL) were included. The samples collected during surgery for membrane. levels of measured using a multiplex bead analysis.The mean logMAR visual acuity was worse (0.42 vs. 0.37; P = 0.331) central thickness higher group (496.9 µm 434.2 µm; 0.007) than they EIFL. 164.1 ± 67.7 group. On analysis cytokines, CD163 (21529 pg/dL 10877 pg/dL;...

This study analyzes a subset of patients with peripapillary polypoidal choroidal vasculopathy (PCV) to determine whether quantifiable pachychoroid features colocalize disease foci.Patients PCV diagnosed by indocyanine green angiography were identified for the analysis medical records and multimodal imaging classified as having or macular PCV. The ratio Haller layer thickness total was calculated at fovea site dilated vessels that showed spatial correlation origin neovascularization....

Purpose: We investigated the outer retinal, RPE, and choroidal changes development of neovascularization (CNV) in fellow eyes patients with unilateral polypoidal vasculopathy or aneurysmal type 1 (PCV/AT1). Methods: In this retrospective observational cohort study, 263 PCV/AT1 were enrolled. Fundus photography, enhanced depth imaging optical coherence tomography, indocyanine green angiography at baseline follow-up analyzed. Incidence risk factors for CNV Results: cases, RPE retinal...

Abstract Background: There has been no study of the effect post end-expiratory pressure (PEEP) on intraocular or intracranial during pneumoperitoneum with steep Trendelenburg positioning. We investigated effects 5 cmH 2 O PEEP and optic nerve sheath diameter as a surrogate for in robot-assisted laparoscopic radical prostatectomy. Methods: Fifty patients scheduled prostatectomy were divided into zero-PEEP (ZEEP) group group. Intraocular pressure, diameter, respiratory hemodynamic parameters...

To investigate the relationships among retinal nonperfusion (NP) area, neovascularization (NV) and aqueous humor vascular endothelial growth factor (VEGF) levels in quiescent proliferative diabetic retinopathy (PDR).Forty-seven eyes from 47 patients with treatment-naïve PDR that did not show macular edema or vitreous hemorrhage were enrolled. NP NV number, area quantitatively measured using ultra-widefield fluorescein angiography an automated manner. Aqueous VEGF level was a bead assay.The...

Purpose: To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients type 2 diabetes mellitus. Methods: Patients without diabetic retinopathy (DR) (n = 54), nonproliferative DR 45), proliferative (PDR) 25), and controls 45) were enrolled. Hemoglobin A1c Early Treatment Diabetic Retinopathy Study (ETDRS) stages of evaluated. Schirmer test (ST), breakup time test, fluorescein corneal staining carried out. Tear height (TMH), depth (TMD), area (TMA)...

Objectives: Controlling blood pressure is a key step in reducing cardiovascular mortality older adults. Gender differences patients’ attitudes after disease diagnosis and their management of the have been identified. However, it unclear whether gender exist hypertension among We hypothesized that would factors associated with control community-dwelling, Methods: This cross-sectional study analyzed data from 653 Koreans aged ≥60 years who participated Korean Social Life, Health, Aging...