Marcos Caique Santana-Silva

ORCID: 0000-0001-6744-1669
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About
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Research Areas
  • RNA Research and Splicing
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms
  • Bacteriophages and microbial interactions
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • SARS-CoV-2 and COVID-19 Research

Universidade Federal do Rio de Janeiro
2021-2022

National Education and Research Network
2021-2022

ABSTRACT The SARS-CoV-2 nucleocapsid protein (N) is a multifunctional promiscuous nucleic acid-binding protein, which plays major role in assembly and discontinuous RNA transcription, facilitating the template switch of transcriptional regulatory sequences (TRS). Here, we dissect structural features N N-terminal domain (N-NTD), either with or without SR-rich motif (SR), upon binding to single double-stranded TRS DNA, as well their activities for dsTRS melting TRS-induced liquid-liquid phase...

10.1101/2021.07.21.453232 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-07-22
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