A5100340277- Radiomics and Machine Learning in Medical Imaging
- Facial Rejuvenation and Surgery Techniques
- Advanced Fiber Laser Technologies
- Cardiac Arrest and Resuscitation
- Burkholderia infections and melioidosis
- Dermatologic Treatments and Research
- MRI in cancer diagnosis
- Alzheimer's disease research and treatments
- Photonic Crystal and Fiber Optics
- Facial Nerve Paralysis Treatment and Research
- Morinda citrifolia extract uses
- Sepsis Diagnosis and Treatment
- Nerve injury and regeneration
- Traditional Chinese Medicine Studies
- Botulinum Toxin and Related Neurological Disorders
- Advanced Fiber Optic Sensors
- Medical Imaging Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Acute Kidney Injury Research
- Lipid metabolism and disorders
- Bacillus and Francisella bacterial research
- Cardiac electrophysiology and arrhythmias
- Machine Learning in Materials Science
- Osteoarthritis Treatment and Mechanisms
- Inflammatory Biomarkers in Disease Prognosis
Shanghai Jiao Tong University
2013-2024
Beijing Shijitan Hospital
2024
Army Medical University
2021-2024
Columbia University
2024
Hebei University
2023-2024
Medomics (China)
2024
Capital Medical University
2020-2024
Zhejiang Chinese Medical University
2013-2024
Shanxi Province Hospital of Traditional Chinese Medicine
2024
Shanghai First People's Hospital
2010-2023
Abstract The development of modern civil industry, energy and information technology is inseparable from the rapid explorations new materials. However, only a small fraction materials being experimentally/computationally studied in vast chemical space. Artificial intelligence (AI) promising to address this gap, but faces many challenges, such as data scarcity inaccurate material descriptors. Here, we develop an AI platform, AlphaMat, that can complete preprocessing downstream models. With...
Abstract Background Poly L‐lactic acid (PLLA) can stimulate fibrous tissue regeneration to exert a filling effect. However, severe inflammatory reactions and unsatisfactory effects remain concern. Objective Herein, we describe the mechanism of action, efficacy, safety PLLA microspheres in suspension (PLLA‐b‐PEG/HA) for facial contouring soft augmentation. Methods PLLA‐b‐PEG/HA, ssynthesized by copolymerization with ethylene glycol, were suspended hyaluronic (HA). Physiological verification...
Mesenchymal stem cells (MSC) have gained credibility as a therapeutic tool partly due to their potential secrete factors such cytokines and chemokines. Recently, exosomes, which mediate intercellular communication by delivering biomolecules mRNA miRNA into recipient cells, attention new valuable strategy in regenerative medicine. However, the role of exosomes secreted adipose-derived mesenchymal (adMSC-Exos) collagen metabolism is not well understood. The purpose this study was evaluate...
ABSTRACT Background The responses to poly‐L‐lactic acid (PLLA) filler implantation exhibit variability across various animal models. This study aimed investigate these differences in order identify suitable models for diverse experimental applications. Methods PLLA fillers were implanted into two distinct skin layers (periosteum and subcutaneous tissue), rabbits, guinea pigs, rats, mice. At 1, 2, 4, 12 weeks postimplantation, biopsy samples collected hematoxylin eosin staining, Masson's...
The nose, eyebrow, and forehead are critical elements of the T-zone, vital for enhancing facial three-dimensionality. Many Asians seek a more contoured sculpted appearance by T-zone augmentation. novel poly-L-lactic acid microsphere hyaluronic suspension (PLLA-b-PEG/HA) has proven to be safe effective dermal filler, making it an appealing choice individuals aiming To retrospectively assess efficacy safety PLLA-b-PEG/HA injection into aesthetic enhancement. Fifteen participants were included...
A high optical signal-to-noise ratio (OSNR) single-frequency 2 μm Brillouin fiber laser (BFL) with watt-level output and transfer efficiency is demonstrated for the first time to best of our knowledge. The pump constructed a two-stage thulium-doped amplifier (TDFA) seeded by diode, providing 4.02 W average power 1 MHz linewidth. Using an optimized length 14 m ring cavity, BFL works stably in single-mode region 8 kHz linewidth because narrowing effect. 51% 1.08 62 dB OSNR 3.22 power.
This study aims to improve the osteogenic differentiation in vitro and bone formation vivo through polycaprolactone (PCL) scaffolds modified with growth peptide (OGP). Three-dimensional (3D)-printed PCL were designed computer-aided design (CAD) software fabricated by 3D layer-by-layer fused deposition. After scaffold surfaces surface amination, OGP was successfully loaded onto using a electrostatic self-assembly method. The effects of these on biocompatibility rat marrow-derived stem cells...
Since the invention of graphene, two-dimensional (2D) materials have attracted great interest in both fundamental science and potential applications. Here, we report saturable absorption features 2D (multilayered structure) molybdenum disulfide (MoS2) mid-infrared (mid-IR) wavelength region, use it to passively Q-switch an Er3+-doped ZBLAN fiber laser at 2.8 µm. This MoS2 absorber has a moderate modulation depth 5% µm, making appropriate candidate for light modulating mid-IR spectral range....
Graphitic carbon nitrides (CNs) have appeared as a new type of photocatalyst for water splitting, but their optical properties (e.g., nonlinear absorption), to the best our knowledge, been seldom explored. Here, we report saturable absorption effects novel 2D carbon-nitride-type nanosheets and use them absorbers passively mode-lock Yb-doped fiber lasers. The CN-based absorber is manufactured by solution coating CN on gold mirror has modulation depth saturation intensity 12.5% 7.5 MW/cm2,...
Myelin and axon losses are associated with cognitive decline in healthy ageing but worse people diagnosed tauopathy. To determine whether tauopathy is also enhanced myelin plasticity, we evaluated the behaviour of OPCs mice that expressed a human pathological variant microtubule-associated protein tau (MAPTP301S ). By 6 months age (P180), MAPTP301S overexpressed hyperphosphorylated had developed reactive gliosis hippocampus not overt locomotor or memory impairment. performing cre-lox lineage...
Abstract Background Polydioxanone (PDO) threads have been widely used to tighten and lift the facial soft tissue. Objective This research aims determine collagenation inflammation changes that occur in adipose tissue over time when different types of are implanted. Methods & Materials Three types, PDO, poly glycolic‐co‐lactic acid (PGLA), nylon, were inserted subcutaneous fat 12‐month‐old Bama miniature pigs. Collagen production inflammatory response evaluated by hematoxylin eosin Masson...
Abstract Background When poly-p-dioxanone (PDO) thread is implanted subcutaneously, in addition to collagen hyperplasia, it can also cause denaturation of surrounding adipocytes and reduce the thickness fat layer. Hitherto, no studies have thoroughly investigated effects PDO on adipose tissue. Objectives In this study, effect tissue was an animal model. Methods current into subcutaneous back a miniature pig. Implantation site control were taken 12 weeks after implantation for hematoxylin...
The clinical management and decision-making process related to breast cancer are based on multiple histological indicators. This study aims jointly predict the Ki-67 expression level, luminal A subtype grade molecular biomarkers using a new deep multitask learning method with multiparametric magnetic resonance imaging. network structure was proposed by introducing common-task layer task-specific layers learn high-level features that common all tasks specific task, respectively. pretrained...
Abstract Background Female androgenetic alopecia (FAGA) is a condition that affects women and involves the gradual loss of terminal hair in specific areas scalp. The limited treatment options for FAGA necessitate development new strategies. This study aimed to evaluate potential benefit using combination therapy composed autologous platelet‐rich plasma (PRP) non‐cross‐linked hyaluronic acid (HA) compound FAGA. Methods was retrospective, case‐series study, which enrolled nine female patients...
Background Horizontal neck wrinkle formation is gaining more attention among cosmetic practitioners and clients. To date, hyaluronic acid products are one of the most common treatment options for this aesthetic concern. However, different therapeutic strategies should be given to solve problem due multiple etiological reasons. Given that oxidative damage plays a critical role in formation, anti-oxidative compounds now considered by physicians when making plan. Aims evaluate efficacy safety...
Background and Objective: The optimization of macrocirculatory hemodynamics is recommended by current sepsis guidelines. However, microcirculatory dysfunction considered the cause severe sepsis. In present study, we designed to verify whether application Shenfu injection (SFI) restores microcirculation, thereby improving tissue perfusion inhibiting organ dysfunction, resulting in improved outcomes. Design: We conducted a prospective, single-center, randomized, double-blind,...
In this letter, we report a digital-wavelength ytterbium-doped fiber laser passively mode-locked with layered molybdenum disulfide (MoS2). The MoS2 based saturable absorber (SA) is made by solution coating the on gold mirror, showing modulation depth and saturation intensity of 11.4% 1.37 MW cm−2, respectively. output pulse has duration ~300 ps, 3 dB spectral width ~0.5 nm maximum power 2.6 mW. fundamental frequency 2.67 MHz ~36 signal-to-noise ratio. Through tuning polarization controller...
Vascular dementia (VD) is one of the leading causes neurological disorder following Alzheimer's disease. The present study evaluated possible role asiaticoside in treatment rats with VD and its inhibitory effects on autophagy hippocampal tissues. Double ligation was used for permanent occlusion arteries, spatial memory assessed using T‑maze test. Western blotting determination protein expression levels H&E staining histological analysis. Treatment significantly alleviated impairment...