A5037925740- Cervical Cancer and HPV Research
- Cancer-related molecular mechanisms research
- Endometrial and Cervical Cancer Treatments
- Macrophage Migration Inhibitory Factor
- Circular RNAs in diseases
- Pelvic floor disorders treatments
- Phytoestrogen effects and research
- Ovarian cancer diagnosis and treatment
- Topic Modeling
- Urological Disorders and Treatments
- Advanced Graph Neural Networks
- Data Quality and Management
- Multimodal Machine Learning Applications
- MicroRNA in disease regulation
- Metal-Organic Frameworks: Synthesis and Applications
- Reproductive System and Pregnancy
- Medicinal Plant Pharmacodynamics Research
- Data Mining Algorithms and Applications
- Urinary and Genital Oncology Studies
- Cancer Immunotherapy and Biomarkers
- Medical Research and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Immunotherapy and Immune Responses
- Venous Thromboembolism Diagnosis and Management
- Molecular Biology Techniques and Applications
Shanxi Academy of Medical Sciences
2014-2025
Shanxi Medical University
2011-2025
Huazhong University of Science and Technology
2022-2024
Tongji Hospital
2022-2024
Shanxi Dayi Hospital
2014-2023
Alibaba Group (China)
2019-2020
Alibaba Group (United States)
2020
Shanxi Provincial Cancer Hospital
2013
Academy of Medical Sciences
2012
First Hospital of Shanxi Medical University
2004-2011
Entity Resolution (ER) identifies records from different data sources that refer to the same real-world entity. Conventional ER approaches usually employ a structure matching mechanism, where attributes are aligned, compared and aggregated for decision. The approaches, unfortunately, often suffer heterogeneous dirty problems. That is, entities described using schemas, attribute values may be misplaced, missing, or noisy. In this paper, we propose deep sequence-to-sequence entity model,...
Entity resolution (ER) aims to identify data records referring the same real-world entity. Due heterogeneity of entity attributes and diversity similarity measures, one main challenge ER is how select appropriate measures for different attributes. Previous methods usually employ heuristic selection algorithms, which are highly specialized specific problems hard be generalized other situations. Furthermore, previous studies perform learning independently, often result in error propagation...
Mesenchymal stem cells (MSC) have gained credibility as a therapeutic tool partly due to their potential secrete factors such cytokines and chemokines. Recently, exosomes, which mediate intercellular communication by delivering biomolecules mRNA miRNA into recipient cells, attention new valuable strategy in regenerative medicine. However, the role of exosomes secreted adipose-derived mesenchymal (adMSC-Exos) collagen metabolism is not well understood. The purpose this study was evaluate...
Entity alignment (EA) aims to identify entities located in different knowledge graphs (KGs) that refer the same real-world object. To learn entity representations, most EA approaches rely on either translation-based methods which capture local relation semantics of or graph convolutional networks (GCNs), exploit global KG structure. Afterward, aligned are identified based their distances. In this paper, we propose jointly leverage structure and entity-specific relational triples for better...
Multi-hop reasoning has been widely studied in recent years to seek an effective and interpretable method for knowledge graph (KG) completion. Most previous methods are designed dense KGs with enough paths between entities, but cannot work well on those sparse that only contain reasoning. On the one hand, less information, which makes it difficult model choose correct paths. other lack of evidential target entities also process difficult. To solve these problems, we propose a multi-hop over...
BACKGROUND Having a gynecological tumor or undergoing treatment can be traumatic experience for women, as it affects their self-image and sexual relationships lead to psychological reactions. Psychological adjustment following cancer occurrence remains key issue among the survivors. AIM To examine current status of quality life (QoL), anxiety, depression in patients with analyze factors associated it. METHODS Data 160 malignancies treated at Shanxi Bethune Hospital from June 2020 2023 were...
Despite the demonstrated efficacy of immune checkpoint blockade therapies in various types cancer, their cervical cancer is limited. A crucial pro‑inflammatory cytokine, macrophage migration inhibitory factor (MIF), highly expressed cancers and contributes to tumor progression via regulation inflammatory responses microenvironment. The present study aimed explore role MIF squamous cell carcinoma (CSCC). Western blotting, reverse transcription‑quantitative polymerase chain reaction,...
Venous thromboembolism (VTE) is a common post-surgical complication of gynecological malignant tumors that has serious implications on the prognosis and quality-of-life patients. However, there exists only few recognized specific evaluation models for occurrence VTE after tumor surgery. We aimed to establish nomogram model could predict probability in patients with malignancies.We collected clinical information 673 who underwent surgery our hospital between January 2014 May 2020. To reduce...
Associations of functional single nucleotide polymorphisms in MIF-173G/C with early stage cervical cancer were investigated a hospital-based case-control study on 250 patients prior to surgery (including 49 cases and 201 without lymphatic metastasis) 147 healthy controls. The polymorphism was assessed using restriction fragment length polymerase chain reaction, the MIF serum concentration examined enzyme-linked immunosorbent assay analyze correlation between concentration. Carriers variant C...
Influence of obesity on surgical complications and survival patients with ovarian tumors were investigated. In total, 362 who diagnosed cancer by biopsy in the Department Pathology Shanxi Dayi Hospital Affiliated to Medical University from April 2012 July 2017 selected as research subjects for retrospective analysis. The divided into group [body mass index (BMI) ≥28] (n=64), overweight (≥24 BMI <28) (n=124), normal body weight (≥18.5 <24) (n=108) low (BMI <18.5) (n=66). conditions...
LncRNA LOXL1-AS1 has been reported to be upregulated in several types of cancer and plays oncogenic roles. We analysed TCGA dataset observed the downregulation cervical squamous cell carcinoma (CSCC). therefore roles CSCC. that was downregulated predicted interact with miR-21, while overexpression experiments showed miR-21 had no significant effects on expression each other. However, led upregulation RHOB, a direct target miR-21. Cell invasion migration analysis decreased rates CSCC cells...
The aims of this study were to investigate microRNA (miRNA) expression profiles in the periurethral vaginal wall tissues postmenopausal women with and without stress urinary incontinence (SUI) explore putative target genes associated SUI via miRNA-messenger RNA (mRNA) pair prediction.Periurethral (n = 13) matched continent collected during transvaginal surgical operation. Total RNAs extracted miRNAs profiled by TaqMan Array Human MicroRNA assays three case-control pairs. TargetScanS, PicTar,...
Cervical cancer (CC) is one of the most common malignant tumors in women. In order to identify functional roles and interaction between mRNA non-coding RNA (ncRNA, including lncRNA, circRNA miRNA) CC cisplatin (DDP) resistance, transcription profile analysis was performed a regulatory model DDP resistance proposed.In this study, whole-transcriptome sequencing conducted study ncRNA profiles parental SiHa cells resistant SiHa/DDP cells. Gene ontology (GO) Kyoto Encyclopedia Genes Genomes...
Objective The aim of the study was to determine whether proportion positive high-risk human papillomavirus (HR-HPV) tests in endocervical specimens transported dry differs from paired liquid media. Methods Five hundred women aged 30 55 years were recruited, Shanxi Bethune Hospital, China. Two samples collected endocervix per patient, one placed into empty vial, other a transport solution. All analyzed by AmpFire HR-HPV assay. Results Total 1,000 500 patients total invalid rate 0.2%...
The objective was to investigate the correlation between macrophage migration inhibitory factor (MIF) promoter polymorphisms (-794CATT5-7 ) and early-stage cervical cancer (ESCC) identify a potential biomarker for ESCC.A hospital-based case-control study performed. case group contained 250 patients with histologically confirmed ESCC. control included 147 healthy women. Polymerase chain reaction-single strand conformation polymorphism used genotype of MIF -794CATT5-7 . Enzyme-linked...
PURPOSE This ongoing trial is comparing the efficacy and safety of three ablation treatments for cervical intraepithelial neoplasia grade 2 or higher. Here, we present early data regarding pain, side effects, acceptability CO gas-based cryotherapy (CO ), nongas cryotherapy, thermal (TA). Efficacy results are expected to become available in late 2023. MATERIALS AND METHODS noninferiority randomized taking place El Salvador, China, Colombia. Patients 1,152 eligible women with biopsy-confirmed...
To report the management of urinary tract obstruction and infection in a pregnant woman with unrepaired bladder exstrophy. A 27-year-old exstrophy was referred to our hospital complaint bilateral flank pain second trimester. After two-dimensional abdominal ultrasound, magnetic resonance imaging urine analysis, she diagnosed an upper due ureteral secondary congenital intrauterine pregnancy. J-tube insertion performed after locating orifices antibiotics were administered. Symptoms rapidly...