- Stroke Rehabilitation and Recovery
- Botulinum Toxin and Related Neurological Disorders
- Acute Ischemic Stroke Management
- Transcranial Magnetic Stimulation Studies
- Cerebral Palsy and Movement Disorders
- Musculoskeletal pain and rehabilitation
- Muscle activation and electromyography studies
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Neurological Disorders and Treatments
- Pain Management and Treatment
- Pain Mechanisms and Treatments
- Dysphagia Assessment and Management
- Atrial Fibrillation Management and Outcomes
- Peripheral Artery Disease Management
- Spatial Neglect and Hemispheric Dysfunction
- Vascular Procedures and Complications
- Peripheral Nerve Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Intraoperative Neuromonitoring and Anesthetic Effects
- Environmental law and policy
- Bone and Joint Diseases
- Trauma Management and Diagnosis
- Advanced Neuroimaging Techniques and Applications
Shirley Ryan AbilityLab
2015-2025
Rancho Research Institute
2024
Northwestern University
2013-2023
Richard Wolf (Germany)
2014-2021
Northwestern Medicine
2018-2019
Pain and Rehabilitation Medicine
2000-2016
Allergan (Ireland)
2012
Foundation for Physical Medicine and Rehabilitation
2012
Middle Georgia State College
2011
Mercer University
1996-2006
Background and Purpose —The aims of this study were to examine the frequency, types, clinical factors associated with medical complications that occur during inpatient rehabilitation identify risk for require a transfer an acute care facility. Methods —A cohort 1029 patients consecutively admitted stroke was studied. Demographic information, impairment, preexisting conditions, admission laboratory abnormalities recorded. Medical complications, defined as new or exacerbated problems,...
Abstract The origins of impaired finger and hand function were examined in 10 stroke survivors with chronic spastic hemiparesis, the intent assessing whether mechanical restraint or altered neurophysiological control mechanisms are responsible for well‐known impairment extension. Simultaneous extension all four metacarpophalangeal (MCP) joints was either externally imposed using a rotary actuator attempted voluntarily by subject. Trials conducted both before after administration local...
Background. This prospective, single-blinded, multicenter study assessed the safety and efficacy of electrical epidural motor cortex stimulation (EECS) in improving upper limb function ischemic stroke patients with moderate to moderately severe hemiparesis. Methods. Patients ≥4 months poststroke were randomized 2:1 an investigational (n = 104) or control 60) group, respectively. Investigational implanted 94) 6-contact lead perpendicular primary a pulse generator. Both groups underwent 6...
Background and Purpose- We aimed to determine whether low-frequency electric field navigated repetitive transcranial magnetic stimulation noninjured motor cortex versus sham avoiding could improve arm function in hemiplegic stroke patients when combined with training. Methods- Twelve outpatient US rehabilitation centers enrolled participants between May 2014 December 2015. delivered 1 Hz active or before each of eighteen 60-minute therapy sessions over a 6-week period, outcomes measured at...
Abstract Background Spasticity is a common impairment that follows stroke, and it results typically in functional loss. For this reason, accurate quantification of spasticity has both diagnostic therapeutic significance. The most widely used clinical assessment the modified Ashworth scale (MAS), an ordinal scale, but its validity, reliability sensitivity have often been challenged. present study addresses deficit by examining whether quantitative measures neural muscular components are...
Ankle movement training is important in motor recovery post stroke and early intervention critical to rehabilitation. However, acute survivors receive rehabilitation only a small fraction of time, partly due the lack effective devices protocols suitable for in-bed Considering first few months recovery, there strong need start early, mobilize ankle, conduct therapy. This study seeks address deliver intensive passive active using wearable ankle robotic device. Isometric torque generation mode...
Assess the effectiveness of intramuscular electrical stimulation in reducing hemiplegic shoulder pain at 12 mos posttreatment.A total 61 chronic stroke survivors with and subluxation participated this multiple-center, single-blinded, randomized clinical trial. Treatment subjects received to supraspinatus, posterior deltoid, middle upper trapezius for 6 hrs/day wks. Control were treated a cuff-type sling Brief Pain Inventory question 12, an 11-point numeric rating scale was administered...
Background. Cortical stimulation (CS) combined with rehabilitation may improve upper limb motor function after stroke. Objective. Describe the study design for Everest Clinical Trial, a randomized single-blinded pivotal device trial, testing safety and efficacy of epidural CS delivered during in patients ischemic Method . A total 174 participants from 21 centers hemiplegia at least 4 months acute stroke are 2:1 ratio to investigational or control groups. Investigational undergo implantation...
Objectives: To investigate the effects of controlled passive stretching and active movement training using a portable rehabilitation robot on stroke survivors with ankle mobility impairment. Methods: Twenty-four patients at least 3 months post st
The aim of this study was to assess the efficacy botulinum toxin type A injections in reducing pain, impairment, and disability patients who have had a stroke with shoulder pain spasticity.In prospective randomized, double-blind, placebo-controlled trial, adults (n = 37) post-stroke spasticity were screened for preinjection spasticity, rated 3 or 4 on Modified Ashworth Scale adductors/internal rotators pain. After baseline screening, 21 subjects randomized receive either onabotulinumtoxinA...
Introduction: The mechanisms of cognitive dysfunction following ischemic cerebellar stroke (CS) are not well understood. Furthermore, traditional clinical MRI protocols often cannot identify subtle and early changes in normal appearing tissue the cerebellum. We aimed to implement an advanced protocol subacute CS patients better understand outcomes. Hypothesis: markers for microstructure cerebrovascular function (CVF) cerebellum will provide mechanistic insight into post-stroke dysfunction....
Objective: To evaluate the feasibility of a fully implanted cortical stimulator for improving hand and arm function in patients following ischemic stroke. Method: Twenty-four chronic stroke with hemiplegia were randomized to targeted electrical stimulation motor cortex upper limb rehabilitation therapy or alone. Results: Using repeated measures regression models, we estimated compared treatment effects between groups over study follow-up period. The investigational group had significantly...
The American Heart Association/American Stroke Association released the adult stroke rehabilitation and recovery guidelines in 2016. A working group of experts reviewed these identified a subset recommendations that were deemed suitable for creating performance measures. These 13 measures are reported here contain inclusion exclusion criteria to allow calculation rates compliance variety settings ranging from acute hospital care postacute home outpatient setting.