David Tirschwell

ORCID: 0000-0002-8059-2901
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About
Contact & Profiles
Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Stroke Rehabilitation and Recovery
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Atrial Fibrillation Management and Outcomes
  • Genetic Associations and Epidemiology
  • Cardiac Arrest and Resuscitation
  • Venous Thromboembolism Diagnosis and Management
  • Neurosurgical Procedures and Complications
  • Blood Pressure and Hypertension Studies
  • Intracranial Aneurysms: Treatment and Complications
  • Cancer-related gene regulation
  • Cardiovascular and Diving-Related Complications
  • Mechanical Circulatory Support Devices
  • Cardiovascular Health and Disease Prevention
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Health and Risk Factors
  • Traumatic Brain Injury Research
  • Lipoproteins and Cardiovascular Health
  • Long-Term Effects of COVID-19
  • Cardiac Arrhythmias and Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • HIV-related health complications and treatments
  • Cardiac Health and Mental Health

University of Washington
2016-2025

Harborview Medical Center
2016-2025

University of Iowa
2020-2024

University of Pittsburgh
2005-2024

University of Thessaly
2024

Arcadia
2024

MIND Research Institute
2024

Memorial Sloan Kettering Cancer Center
2024

University of Minnesota
2024

Cornell University
1992-2024

The American Heart Association, in conjunction with the National Institutes of Health, annually reports on most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data a range major clinical circulatory disease conditions (including congenital rhythm disorders,...

10.1161/cir.0000000000000757 article EN cc-by-nc Circulation 2020-01-29

Whether closure of a patent foramen ovale is effective in the prevention recurrent ischemic stroke patients who have had cryptogenic unknown. We conducted trial to evaluate whether superior medical therapy alone preventing or early death 18 60 years age.In this prospective, multicenter, randomized, event-driven trial, we randomly assigned patients, 1:1 ratio, ovale. The primary results were analyzed when target 25 end-point events been observed and adjudicated.We enrolled 980 (mean age, 45.9...

10.1056/nejmoa1301440 article EN New England Journal of Medicine 2013-03-20

Whether closure of a patent foramen ovale reduces the risk recurrence ischemic stroke in patients who have had cryptogenic is unknown.

10.1056/nejmoa1610057 article EN New England Journal of Medicine 2017-09-13

Research based on administrative data has advantages, including large numbers, consistent data, and low cost. This study was designed to compare different methods of stroke classification using data.Administrative hospital discharge medical record review 206 patients were used evaluate 3 algorithms for classifying patients. These all (algorithm 1), the first 2 2), or primary 3) diagnosis code(s). The diagnoses after considered gold standard. Then, a set, we compared with their code in...

10.1161/01.str.0000032240.28636.bd article EN Stroke 2002-10-01

Withdrawal of support in patients with severe brain injury invariably leads to death. Preconceived notions about futility care intracerebral hemorrhage (ICH) may prompt withdrawal support, and modeling outcome patient populations whom occurs lead self-fulfilling prophecies.Subjects included consecutive supratentorial ICH. Radiographic characteristics the hemorrhage, clinical variables, neurologic were assessed. Attitudes examined among members departments neurology surgery through a written...

10.1212/wnl.56.6.766 article EN Neurology 2001-03-27

The authors identified 298 diagnoses of moyamoya in California and Washington from hospital discharge databases during the period 1987 to 1998. incidence was 0.086/100,000 persons. ethnicity-specific rate ratios compared whites were 4.6 (95% CI: 3.4 6.3) for Asian Americans, 2.2 1.3 2.4) African 0.5 0.3 0.8) Hispanics. lower than reported Japan, but among U.S. Asians is similar.

10.1212/01.wnl.0000176066.33797.82 article EN Neurology 2005-09-27

<h3>Importance</h3> Many patients receive suboptimal rehabilitation therapy doses after stroke owing to limited access therapists and difficulty with transportation, their knowledge about is often limited. Telehealth can potentially address these issues. <h3>Objectives</h3> To determine whether treatment targeting arm movement delivered via a home-based telerehabilitation (TR) system has comparable efficacy dose-matched, intensity-matched in traditional in-clinic (IC) setting, examine this...

10.1001/jamaneurol.2019.1604 article EN JAMA Neurology 2019-06-25

Although studies have attempted to differentiate intracranial vascular disease using vessel wall magnetic resonance imaging (VWI), none incorporated multicontrast imaging. This study uses T1- and T2-weighted VWI vasculopathies.We retrospectively reviewed patients with clinically defined vasculopathies causing luminal stenosis/irregularity who underwent studies. Two blinded experts evaluated T1 precontrast postcontrast characteristics, including the pattern of thickening; presence, pattern,...

10.1161/strokeaha.115.009037 article EN Stroke 2015-05-08

The incidence and prevalence of most cardiovascular disorders increase with age, disease is the leading cause death major disability in adults ≥75 years age; however, despite large impact on quality life, morbidity, mortality older adults, patients aged have been markedly underrepresented trials, virtually all trials excluded complex comorbidities, significant physical or cognitive disabilities, frailty, residence a nursing home assisted living facility. As result, current guidelines are...

10.1161/cir.0000000000000380 article EN Circulation 2016-04-12
Hooman Kamel W. T. Longstreth David Tirschwell Richard A. Kronmal Randolph S. Marshall and 95 more Joseph P. Broderick Rebeca Aragón García Pamela Plummer Noor Sabagha Qi Pauls Christy Cassarly Catherine Dillon Marco R. Di Tullio Eldad A. Hod Elsayed Z. Soliman David J. Gladstone Jeff S. Healey Mukul Sharma Seemant Chaturvedi L. Scott Janis Balaji Krishnaiah Fadi Nahab Scott E. Kasner Robert J. Stanton Dawn Kleindorfer Matthew Starr Danilo Toni Wayne M. Clark Benjamin Miller Mitchell S.V. Elkind Ganesh Asaithambi Maxwell Klaiman Konark Malhotra Mary Fetter Anna Wanahita Stacie Merritt Rehan Sajjad Kate McPolin Bruce M. Coull Shriya Kavathia Murali Kolikonda S Calhoun Felipe De Los Rios La Rosa Ian Del Conde Josette Elysée Amin Aghaebrahim Melissa Stratoberdha Andria L. Ford James Giles Yan Wang Jennifer Babka Rahul Damani Barbara Gutierrez-Flores Sandeep Kumar Sarah Marchina Marc Swerdloff Margaret Scott Amandeep Sangha Kelly Patterson Julie Shulman Steven K. Feske José R. Romero Hugo J. Aparicio David M. Greer Rebecca Stafford Arturo Tamayo Leanne Anderson Stelios M. Smirnakis Quinn Rademaker Maurice Hourihane Robert G. Sawyer Marilou Ching Amit Kandel Rakesh Magun Annemarie Crumlish Annaliese Bosco Sanjay Singh Abhishek Singh Elizabeth Traynor Ram Mohan Sankaraneni Toufik Mahfood Haddad Carly C. Isder L. Larsen Rasmussen Dustin Rochestie Nancy Brunetti Dhruvil J. Pandya Rosemarie R. Baligod Dan J. Capampangan Allegra Sahelian Jason T. Nomura Kimberly Gannon Jonathan Raser-Schramm Kathleen Murphy Ahmed Itrat Debra Hudock Dolora Wisco Laura Sweeney William Likosky Rebekah Garcia H Schumacher

Importance Atrial cardiopathy is associated with stroke in the absence of clinically apparent atrial fibrillation. It unknown whether anticoagulation, which has proven benefit fibrillation, prevents patients and no Objective To compare anticoagulation vs antiplatelet therapy for secondary prevention cryptogenic evidence cardiopathy. Design, Setting, Participants Multicenter, double-blind, phase 3 randomized clinical trial 1015 participants cardiopathy, defined as P-wave terminal force...

10.1001/jama.2023.27188 article EN JAMA 2024-02-07

To perform a health maintenance organization-based case-control study to evaluate the association of total and high density lipoprotein (HDL) cholesterol with risk stroke subtypes in patient subgroups.Cases had confirmed incident ischemic (n = 1,242) or hemorrhagic 313). Controls 6,455) were identified companion myocardial infarction study. Risk was modeled using logistic regression.The highest quintile associated an increased compared lowest (OR 1.6, 95% CI 1.3 2.0) strongest subtype...

10.1212/01.wnl.0000144282.42222.da article EN Neurology 2004-11-23

Object. The goal of this study was to determine whether a hospital's volume subarachnoid hemorrhage (SAH) cases affects mortality rates in patients with SAH. For certain serious illnesses and surgical procedures, outcome has been associated hospital case volume. Subarachnoid hemorrhage, usually resulting from ruptured cerebral aneurysm, yields high rate. There no multistate diverse set hospitals in-hospital are influenced by SAH cases. Methods. authors conducted an analysis retrospective,...

10.3171/jns.2003.99.5.0810 article EN Journal of neurosurgery 2003-11-01

Hematomas that enlarge following presentation with primary intracerebral hemorrhage (ICH) are associated increased mortality, but the mechanisms of hematoma enlargement poorly understood. We interpreted presence contrast extravasation into after CT angiography (CTA) as evidence ongoing and sought to identify clinical significance well factors risk extravasation.We reviewed records radiographic studies all patients intracranial undergoing CTA from 1994 1997. Only ICH were included in this...

10.1161/01.str.30.10.2025 article EN Stroke 1999-10-01
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