A5078621943- Neuroendocrine regulation and behavior
- Evolutionary Psychology and Human Behavior
- Attachment and Relationship Dynamics
- Traumatic Brain Injury and Neurovascular Disturbances
- Primate Behavior and Ecology
- Spinal Fractures and Fixation Techniques
- Stress Responses and Cortisol
- Physiological and biochemical adaptations
- Traumatic Ocular and Foreign Body Injuries
- Child and Animal Learning Development
- Pelvic and Acetabular Injuries
- Hormonal and reproductive studies
- Human-Animal Interaction Studies
- Intracranial Aneurysms: Treatment and Complications
- Neuroscience of respiration and sleep
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sexual Differentiation and Disorders
- Neurosurgical Procedures and Complications
- Ophthalmology and Eye Disorders
- Marine animal studies overview
- Facial Trauma and Fracture Management
- Cerebral Venous Sinus Thrombosis
- Lanthanide and Transition Metal Complexes
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
University of California, Davis
2019-2025
Cornell University
2024
Weill Cornell Medicine
2024
New York University
2006-2023
Bellevue Hospital Center
2016-2023
Primate Conservation
2022
Oregon National Primate Research Center
2021
Brigham Young University
2017-2019
NYU Langone Health
2016
New York Eye and Ear Infirmary
2003-2004
Withdrawal of support in patients with severe brain injury invariably leads to death. Preconceived notions about futility care intracerebral hemorrhage (ICH) may prompt withdrawal support, and modeling outcome patient populations whom occurs lead self-fulfilling prophecies.Subjects included consecutive supratentorial ICH. Radiographic characteristics the hemorrhage, clinical variables, neurologic were assessed. Attitudes examined among members departments neurology surgery through a written...
Hematomas that enlarge following presentation with primary intracerebral hemorrhage (ICH) are associated increased mortality, but the mechanisms of hematoma enlargement poorly understood. We interpreted presence contrast extravasation into after CT angiography (CTA) as evidence ongoing and sought to identify clinical significance well factors risk extravasation.We reviewed records radiographic studies all patients intracranial undergoing CTA from 1994 1997. Only ICH were included in this...
Injuries to the atlanto-occipital region, which range from complete or atlantoaxial dislocation nondisplaced occipital condyle avulsion fractures, are usually of critical clinical importance. At initial cross-table lateral radiography, measurement basion-dens and basion-posterior axial line intervals comparison with normal measurements may help detect injury. Computed tomography (CT) sagittal coronal reformatted images permits optimal detection evaluation fracture luxation. CT findings that...
We proposed to characterize the radiologic spectrum of occipital condyle fractures in a large series patients and correlate fracture pathology with neurosurgical treatment patient outcome.We conducted retrospective review findings on conventional radiography, CT, MR imaging 95 107 fractures. described patterns according two previously published classification systems. Clinical findings, management, outcome were obtained from medical records.Inferomedial avulsions (Anderson Montesano type...
Recent research has shown that personality similarity between pair-bonded individuals can lead to better compatibility and well-being in humans. In our study, we explored the of 27 pairs captive coppery titi monkeys (Plecturocebus cupreus), using a Hominoid Personality Questionnaire 54 items. We also examined effect pair duration, affiliation, presence offspring on these pairs. built model with five components describe monkey structure colony labeled as aggressive, cool, cautious,...
Intranasal oxytocin (IN OXT) administration has been proposed as a pharmacological treatment for range of biomedical conditions including neurodevelopmental disorders. However, studies evaluating the potential long-lasting effects chronic IN OXT during development are still scarce. Here we conducted follow-up study cohort adult titi monkeys that received intranasal 0.8 IU/kg (n = 15) or saline 14) daily six months their juvenile period (12 to 18 age), with goal behavioral and neural one year...
Abstract Environmental and biological factors contribute to sleep development during infancy. Parenting plays a particularly important role in modulating infant sleep, potentially via the serotonin system, which is itself involved regulating sleep. We hypothesized that maternal neglect system dysregulation would be associated with daytime rhesus monkeys. Subjects were nursery-reared macaques ( n = 287). During first month of life, sleep-wake states rated bihourly (0800–2100). Infants...
Baxter AB, Melnikoff S, Stites DP, Brasch RC. Immunogenicity of gadolinum-based contrast agents for magnetic resonance imaging: induction and characterization antibodies inanimals. Invest Radiol 1991;26:1035–1040.To evaluate the immunogenic potential gadolinium-based imaging (MRI) agents, Sprague-Dawley rats weresensitized with gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) dimeglumine Gd-DTPA covalently linked to either human serum albumin, dextran, or polylysine. IgG directed...
Abstract Social cognition is facilitated by oxytocin receptors (OXTR) in the hippocampus, a brain region that changes dynamically with pregnancy, parturition, and parenting experience. We investigated impact of parenthood on hippocampal OXTR male female titi monkeys, pair-bonding primate species exhibits biparental care offspring. hypothesized postmortem tissue, binding formation would differ between parents non-parents, density correlate frequencies observed affiliative behaviors partners....
Abstract The second‐to‐fourth digit (2D:4D) ratio is a sexually‐dimorphic biomarker for prenatal sex hormone exposure. We investigated whether titi monkeys ( Plecturocebus cupreus ) exhibit 2D:4D ratio, and variation in correlates with maternal testosterone estrogen levels during early pregnancy. Subjects were 61 adult (32 males, 29 females). For 26 subjects, urine samples collected approximately 15–20 weeks before birth assayed estrone conjugate (E 1 C). Titi exhibited human‐like pattern of...
Prenatal androgen exposure (PAE) plays a pivotal role in masculinizing the developing body and brain, extreme may contribute to autism, anxiety disorder schizophrenia. One commonly used biomarker for PAE is pointer-to-ring-finger digit length (2D:4D) ratio. Although this widely human studies, relatively few studies have investigated 2D:4D ratio nonhuman primates, particularly rhesus macaques (Macaca mulatta), one of most animals biomedical research. Thus far, data suggest that sexual...
Romantic first impressions seem to linger, but why? Few studies have investigated how romantic desire during initial interactions predicts later relational outcomes (e.g., interest, contact attempts) using a design that can tease apart different possible mechanisms mate value, selectivity, compatibility). Across three speed-dating ( n = 559) with longitudinal follow-ups (including college and community samples, sample of men who date men), we whether components predicted relationship...
RATIONALE AND OBJECTIVES. To investigate the mechanism of anaphylactoid reactions to contrast media, in vitro histamine release induced by magnetic resonance imaging, and iodinated agents was examined a dog mastocytoma cell line. METHODS. Two gadolinium (Gd)-based agents, Gd diethylenetriamine pentaacetic acid (Gd-DTPA), dimeglumine, Gd-bismorpholide, two diatrizoate meglumine iohexol, were incubated with histamine-containing canine cells. Release into supernatant determined at various...
Abstract Behavioral compatibility plays a critical role in shaping how potential mates interact with and evaluate each other whether they choose to pursue relationship. Compatibility is especially important for mate choice relationship quality pair‐bonding species that form long‐term attachments between mates. Although this process has been studied humans birds, relatively few studies have investigated it non‐human primates. In study, we pairing titi monkeys ( Plecturocebus cupreus ) based...
Delayed cerebral artery pseudoaneurysm after nail gun injury.B A Blankenship, B Baxter and G M McKahn, 2ndAudio Available | Share
Abstract Social bonds influence physiology and behavior, which can shape how individuals respond to physical affective challenges. Coppery titi monkey ( Plecturocebus cupreus ) offspring form selective with their fathers, making them ideal for investigating father–daughter juveniles’ responses oxytocin (OT) arginine‐vasopressin (AVP) manipulations. We quantified the expression of bond‐related behaviors in females n = 10) gave acute intranasal treatments saline, low/medium/high OT, low/high...
Abstract Parenting induces many neurological and behavioral changes that enable parents to rear offspring. Vasopressin plays an important role in this process via its effects on cognition, affect, neuroplasticity, some cases, interactions with decreased parental androgens. Thus far, the of these hormones has been primarily studied rodents. To address gap, we explored vasopressin receptors androgens titi monkeys, a pair‐bonding biparental primate species. In Studies 1 2, used receptor...
Steroid hormones are critical to the regulation of sociosexual behavior. Their role in formation pair bonds is complicated by relative scarcity this social system mammals, as well species and taxonomic differences endocrine systems. In present study, we experimentally manipulated hypothalamic–pituitary-adrenal axis female titi monkeys (Plecturocebus cupreus), a neotropical monkey studied for its strong, selective bonds. We validated an assay plasma urinary cortisol species, showing strong...
Gould R, Brasch RC, Sievers Baxter A, Aicher K. Comparison of vascular opacification after bolus injection iodixanol-320 and iohexol-350. Invest Radiol 1992;27:1031–1034. RATIONALE AND OBJECTIVES. The characteristics a new nonionic, dimeric contrast agent, iodixanol, have been compared with monomeric iohexol, using ultrafast computed tomography (UFCT). METHODS. In 10 experiments mongrel dogs, the agents were alternately injected into animal's left atrium, UFCT images obtained at four...