A5017879739- Reproductive Biology and Fertility
- Ovarian function and disorders
- Hemoglobinopathies and Related Disorders
- Birth, Development, and Health
- Thyroid Cancer Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Thyroid Disorders and Treatments
- Diet, Metabolism, and Disease
- Growth Hormone and Insulin-like Growth Factors
- Peroxisome Proliferator-Activated Receptors
- Sexual Differentiation and Disorders
- Genetic Associations and Epidemiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- MicroRNA in disease regulation
- Nutritional Studies and Diet
- S100 Proteins and Annexins
- Ovarian cancer diagnosis and treatment
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Vitamin D Research Studies
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Hormonal and reproductive studies
- Metabolism, Diabetes, and Cancer
- Meta-analysis and systematic reviews
Research Institute for Endocrine Sciences
2015-2024
Shahid Beheshti University of Medical Sciences
2015-2024
Indianapolis Zoo
2022
Denver School of Nursing
2022
Triangle
2022
Gainesville Obstetrics & Gynecology
2022
Committee on Publication Ethics
2022
Shahid Beheshti University
2013
Zahedan University of Medical Sciences
2008-2012
Pasteur Institute of Iran
2003
Abstract Hashimoto’s thyroiditis (HT) is the most prevalent autoimmune disorder characterized by destruction of thyroid cells caused leukocytes and antibody-mediated immune processes accompanied hypothyroidism. In recent years, evidence has emerged pointing to various roles for vitamin D, including, proliferation differentiation normal cancer cells, cardiovascular function, immunomodulation. Vitamin D deficiency been especially demonstrated in HT patients. The aim this study was investigate...
To evaluate cross-sectional and longitudinal relationships between sugar sweetened beverages (SSBs), carbonated soft drinks (SSSDs), fruit juice drink consumption risk of chronic kidney disease (CKD) in a population based study.At baseline, 2382 participants, aged >27 years, the Tehran Lipid Glucose Study with complete data on serum creatinine, cardio-metabolic factors, diet were included for analysis. After 3 1690 subjects, free baseline CKD follow-up data, Estimated glomerular filtration...
This study was designed to examine the hypothesis that dietary of intake different types fiber could modify risk cardiovascular disease (CVD) in a large prospective cohort among Iranian adults.In 2006-2008, we used validated food frequency questionnaire assess 2295 health professionals with no previous history heart disease. Subjects were subsequently followed until 2012 for incidence CVD events. Multivariate Cox proportional hazard regression models, adjusted potential confounders estimate...
Although the positive relationship between insulin resistance (IR) and central obesity is well known, direct waist circumference IR not clear yet there no consensus regarding cut off value for as a surrogate index obesity. The present study was aimed to determine optimal cut-off of (WC) predicting in reproductive aged Iranian women.Using stratified, multistage probability cluster sampling method 1036 women were randomly selected from among different geographic regions Iran. Following...
Limited data are available regarding the association of major dietary patterns and risk cardiovascular disease (CVD) in Middle Eastern countries. We aimed to evaluate patterns, using factor analysis, with CVD. Participants without CVD (n = 2284) were recruited from Tehran Lipid Glucose Study followed for a mean 4.7 years. Dietary intake participants was assessed at baseline (2006–2008); biochemical variables evaluated follow-up examination. Multivariate Cox proportional hazard regression...
The aim of the present study was to investigate association between matrix metalloproteinase-9 (MMP-9) expression with BRAF V600E mutation and clinicopathological features, in Iranian papillary thyroid cancer (PTC) patients. In total, 90 participants including 60 PTC patients (15 males 45 females) 30 individuals benign multinodular goiter (MNG) (5 25 which were confirmed by surgical pathology, investigated. MMP-9 evaluated at both mRNA protein levels, using SYBR-Green Real-Time PCR...
Peroxisome proliferator-activated receptor gamma (PPARγ) is a promising therapeutic molecule. Epigenetic mechanisms, including non-coding RNAs, regulate the expression level of PPARγ gene.We aimed to examine in non-diabetic individuals four body mass index (BMI) categories and its association with miR-34a miR-143 expression.Visceral subcutaneous adipose tissues (VAT SAT) samples were collected from patients undergoing bariatric or elective open abdominal surgeries. The subjects (mean age:...
To determine the molecular spectrum of β-thalassemia mutations among at-risk Balouch couples in Iran.Mutations' detection DNAs extracted from blood partners was characterized, and chorion villus sampling by amplification refractory mutation system DNA sequencing performed. Fetal diagnosis also confirmed linkage analysis.Out a total 1234 referred to center for prenatal (PND) June 2002 2010, high percentage '67.4%' were consanguineous marriages 37.4% had between one four affected children. The...
Transient congenital hypothyroidism (TCH) could disturb carbohydrate metabolism in adulthood. Aging is associated with increased risk of type 2 diabetes. This study aims to address effects TCH on mRNA expressions glucose transporters (GLUTs) and glucokinase (GcK) islets insulin target tissues aged offspring rats.The group received water containing 0.025% 6-propyl-2-thiouracil during gestation. Offspring from control groups (n=6 each group) were followed until month 19. Gene GLUTs GcK...
This study aimed to characterize the molecular spectrum of β-thalassemia (β-thal) mutations and evaluate services available for prenatal diagnosis (PND) among Sistani population Iran. Mutations were analyzed with amplification refractory mutation system (ARMS), gap-polymerase chain reaction (gap-PCR), multiplex ligation-dependent probe (MLPA) analysis direct sequencing. Fetal was also confirmed by linkage analysis. Over a 9-year period (2002-2011), 405 at-risk couples referred and/or PND. Of...