A5082605285- Lysosomal Storage Disorders Research
- Renal Diseases and Glomerulopathies
- Environmental Sustainability in Business
- Parasitic Diseases Research and Treatment
- Biochemical and Molecular Research
- T-cell and B-cell Immunology
- Cellular transport and secretion
- Studies on Chitinases and Chitosanases
- Probiotics and Fermented Foods
- Enzyme Production and Characterization
- Health, Nursing, Elderly Care
- Diverse Aspects of Tourism Research
- Inflammatory mediators and NSAID effects
- Carbohydrate Chemistry and Synthesis
- Biomedical Research and Pathophysiology
- Cleft Lip and Palate Research
- Phytochemistry Medicinal Plant Applications
- Maternal and Neonatal Healthcare
- Environmental Education and Sustainability
- Biotechnology and Related Fields
- Plant-Derived Bioactive Compounds
- Genetic and Kidney Cyst Diseases
- Complement system in diseases
- Education during COVID-19 pandemic
- Tourism, Volunteerism, and Development
Universidade Federal do Piauí
2012-2025
Universidade Estadual do Piau
2025
Secretaria da Saúde
2022-2024
Faculdade de Tecnologia e Ciências
2022
Barcelona Institute for Global Health
2020
University of Pittsburgh
2016
Hospitais da Universidade de Coimbra
2014
University of Stavanger
2012
Conservatoire National des Arts et Métiers
2010-2012
Universidade Federal de Minas Gerais
2001
The overall aim of this case study was to further the understanding tour guides' contribution sustainable tourism. First, it expands on Cohen's (1985 Cohen, E. 1985. tourist guide: origins, structure and dynamics a role. Annals Tourism Research, 12: 5–29. Retrieved from http://dx.doi.org/10.1016/0160-7383(85)90037-4[Crossref], [Web Science ®] , [Google Scholar]) Weiler Davis' (1993) schematic representation roles by adding an "economy sphere" encompass principles. Second, examines congruence...
Aims: This article aims to evaluate the phytochemical characteristics and biological activity of Cinnamomum cassia Blume zeylanicum essential oils, specifically their effects on weight loss, diarrhea, epithelial damage in a murine model 5-fluorouracil-induced intestinal mucositis. Study Design: The study consisted controlled experimental design using therapeutic potential oils mucositis induced by chemotherapy with 5-FU. Location: research was conducted at Medicinal Plant Research Center...
Aims: This study aimed to design and validate primers investigate the expression of key genes canonical inflammation pathway, specifically NEMO (NF-kappaB Essential Modulator), MyD88 IL-1β, in order ensure feasibility, specificity efficiency for use RT-qPCR. Study Design: is an experimental at validation using silico strategies. Methodology: FASTA sequences pathway were obtained from NCBI database open reading frames (ORFs) identified ORF Finder tool, while conserved domains annotated...
Both mucus and mucosa-associated bacteria form a specific environment in the gut; their disruption may play crucial role development of intestinal bowel disease (IBD). Metronidazole, an antibiotic used treatment IBD, alters gut microbiota reduces basal oxidative stress to proteins colonic tissue healthy rats. The aim this study was evaluate impact altered due metronidazole on thickness layer. This performed untreated rats (control group) or treated by (metronidazole-treated rats, 1 mg mL(-1)...
Purpose This paper aims to explore relationships between consumers' sustainable purchasing practices and their related cognitions, evaluations, beliefs when considering purchases of tourist products or general goods. Design/methodology/approach “Cognitions” refers familiarity with the concept “environmentally‐friendly”, “evaluations” are considerations importance responsible practices, “beliefs” convictions effects buying environmentally‐friendly products. Data were collected by...
Many epidemiological and experimental studies have suggested an important role for dietary fibre (DF) of cereals in the prevention colon cancer. The objective present study was to explain effects DF barley Rihane (BR) on azoxymethane (AOM)-induced aberrant crypt foci (ACF) colonic bacterial diversity rats. Following acclimatisation period, rats were divided into four groups fed a control (C) diet or containing 30 % BR. content twice that C (total 8·69 15·24 BR diet). At 7 8 weeks age,...
Fabry nephropathy is a major cause of morbidity and premature death in patients with disease (FD), rare X-linked lysosomal storage disorder. Gb3, the main substrate α-galactosidase A (α-Gal A), progressively accumulates within cells variety tissues. Establishment cell models has been useful as tool for testing hypotheses pathogenesis. We applied CRISPR/Cas9 genome editing technology to GLA gene develop human kidney FD immortalized podocytes, which are affected renal type. Our podocytes lack...
Resumo Introdução: A doença de Fabry (DF) é uma desordem lisossômica ligada ao cromossomo X ocasionada por mutações no gene que codifica a enzima α-galactosidase (α-GAL). redução ou ausência da atividade dessa leva acúmulo progressivo gb3. renal importante consequência clínica acumulação Gb3. Podócito o tipo celular mais afetado na renal, mostra apenas resposta parcial à Terapia Reposição Enzimática. Além disso, disfunção podocitária principal contribuinte para perda progressiva função e...
The present study examines the extent to which topics of sustainability – considered innovative subjects in guiding are included guide training programmes eight European countries. To best our knowledge, this is first its kind Europe. It assumed that tourist guides have unique opportunity improve visitors’ understanding and appreciation a destination thus contribute sustainability. Data were collected from institutions Belgium, France, Hungary, Italy, Malta, Netherlands, Norway Spain, all...
The quest for an ideal biomaterial perfectly matching the microenvironment of surrounding tissues and cells is endless challenge within biomedical research, in addition to integrating this with a facile sustainable technology its preparation. Engineering hydrogels through click chemistry would promote invention tailor-made hydrogels. Herein, we disclose versatile catalyst-free generation innovative hydrogel by combining chondroitin sulfate (CS) polyethylene glycol (PEG). Various multi-armed...
Bowel-associated dermatosis-arthritis syndrome (BADAS) is a neutrophilic dermatosis, characterized by the occurrence of arthritis and skin lesions related to bowel disease with or without bypass. We report an unusual case BADAS in 15-year-old white male congenital aganglionosis colon hypoganglionosis small intestine multiple surgeries childhood complicated short syndrome. He presented recurrent peripheral polyarthritis, tenosynovitis, painful erythematous subcutaneous nodules located on...
De seis amostras de pernil desossado curado e três salame tipo italiano artesanal foram isoladas 288 cepas bactérias lácticas. Pelo teste inibição direta 59 delas capazes inibir in vitro o desenvolvimento Listeria monocytogenes Staphylococcus aureus, que demonstra produzem compostos inibitórios.
Background : To evaluate the influence of previous physical activity (PA) during childhood, adolescence, and current PA practice on production antibodies inflammatory response between first second doses COVID-19 vaccine. Methods Fifty-nine men 56 women were evaluated before vaccine, 12 weeks later, blood samples taken to quantify anti-severe acute respiratory syndrome coronavirus-2 immunoglobulin G cytokines. Previous childhood adolescence was self-referred, assessed using International...
A análise cromossômica, uma prática clinicamente crucial realizada tradicionalmente por geneticistas, pode ser suscetível à fadiga ao longo do tempo, afetando a qualidade dos diagnósticos. Neste artigo, exploramos classificação automatizada de imagens cromossomos meio diversas arquiteturas redes neurais profundas. Avaliamos 23 pares humanos em tarefa multiclasse, revelando resultados promissores. Destacam-se os desempenhos superiores da arquitetura DenseNet169, alcançando acurácia, precisão,...
As doenças raras, afetando cerca de 13 milhões brasileiros, enfrentam desafios significativos no diagnóstico e tratamento devido à falta infraestrutura conhecimento especializado. Este estudo descreve a implantação padronização do teste qualitativo porfobilinogênio (PBG) Laboratório Imunogenética Biologia Molecular da Universidade Federal Piauí (LIB-UFPI), visando ao Porfiria Intermitente Aguda (PIA). A Ehrlich permitiu oferta uma ferramenta diagnóstica acessível em região com recursos...