A5056276215- Plant Toxicity and Pharmacological Properties
- Pesticide Exposure and Toxicity
- Seed and Plant Biochemistry
- HIV/AIDS drug development and treatment
- Ethnobotanical and Medicinal Plants Studies
- Biochemical and biochemical processes
- Epilepsy research and treatment
- Natural Antidiabetic Agents Studies
- Cancer, Lipids, and Metabolism
- Computational Drug Discovery Methods
- Plant-based Medicinal Research
- Higher Education and Sustainability
- Nutrition, Genetics, and Disease
- Pharmacological Effects and Toxicity Studies
- Insect and Pesticide Research
- Environmental and sustainability education
- Digestive system and related health
- Lipoproteins and Cardiovascular Health
- Phytochemicals and Antioxidant Activities
- Cancer Treatment and Pharmacology
- Phytochemistry and biological activity of medicinal plants
- Pesticide and Herbicide Environmental Studies
- Glioma Diagnosis and Treatment
- Weed Control and Herbicide Applications
- Social Issues and Sustainability
Universidad Científica del Sur
2022-2025
Universidad de Lima
2022-2025
The major production of artisanal and industrial wines is elaborate in the Ica Valley, Peru. objective was to evaluate antioxidant activity polyphenols permissible values glyphosate from Pisco Routes Samples: six coded two commercial brands as references (60088 60089). Total polyphenol content (TPC) found between 107.90 ± 0.30 (60091) 234.73 0.61 mg GAE/100 mL (60084); total flavonoid (TFC) 9.70 16.83 0.25 QE/100 (60084). Antioxidant activity: DPPH 34.9 0.44 55.6 mM TEAC/100 (60085). FRAP...
The CYP1A1 isoenzyme is responsible for the biotransformation of procarcinogens, such as Benzo(a)pyrene, into reactive metabolites. Meanwhile, GSTM1 facilitates detoxification these metabolites by conjugating them with glutathione. presence CYP1A1*2A genetic variant intensifies production metabolites, and deletion gene ( GSTM1*0 ) impairs their detoxification. This enzymatic imbalance leads to formation DNA adducts, which are known contribute cancer other diseases. Given importance studying...
Heliotropium arborescens (Galán de Mera et al. 2022) is a herbaceous plant that contains various biophenolic compounds exhibit antibacterial property and antioxidant activity could prevent diseases caused by free radicals. The objective was to study the metal ions associated with in vitro of ethanolic extract L. leaves from Andean region Ayacucho-Peru. total polyphenolic content (TPC) determined Folin-Ciocalteu method; Total flavonoid (TFC) spectrophotometry at 510 nm, TFC expressed mg...
Context: Acute inflammation due to persistent stimulation of noxes evolves into chronic that contributes the pathogenesis asthma, arthritis, atherosclerosis, diabetes, aging, and cancer; therefore, it is justified study plants with anti-inflammatory activity fewer adverse effects. Aims: To evaluate potential effect total flavonoid content hydroalcoholic extract leaves Senna alata (L.) Roxb (HELSA) in an experimental model acute induced by carrageenan rats. Methods: The (TFC) was determined...
Currently, there is a greater interest in using natural products various chronic diseases such as type 2 diabetes. However, these investigations have not considered the components of grape seeds. In this context, current study explored vitro antioxidant and vivo hypoglycemic activity biophenols total polyunsaturated fatty acids (PUFA) from Vitis vinifera L. muscat quebranta seeds Ica Valley, Peru. The polyphenol content (TPC) (1.57±0.015 mg GAE/g) (1.43±0.015 was estimated by Folin-Ciocalteu...
Context: Therapeutic drug monitoring (TDM) allows personalizing the dose of valproic acid in patients with epilepsy to optimize therapy, minimize adverse effects and detect interactions. Aims: To determine concentrations serum samples from people analyze its clinical implications. Methods: Cloned donor enzyme immunoassay; descriptive, cross-sectional, non-randomized, convenience recruitment study 57 voluntary (n = 39 male, 68.42%; n 18 female, 31.58%) aged between 19 62 years. After three...
Context: In 14 districts of the valley Ica-Peru, Vitis vinifera L. plants are cultivated that produce grapes for consumption as table and raisins (dried grapes); at same time, production wines Piscos. Aims: To determine levels abamectin emamectin in L from a district Valley Ica-Peru. Methods: 30 lots (30 kg) Moscatel grape variety V. were collected six countryside (artisanal organic cultivation) San Juan Bautista district. The extraction (ABM) benzoate (EMB) was carried out with...
Context: Statins reduce the risk of stroke and prevent cardiac events in people with atherosclerosis diabetes mellitus; could affect proliferation, migration, survival cancer cells. Aims: To review most up-to-date available scientific evidence on allelic variants SLCO1B1 CYP3A4 associated pharmacokinetic interactions adverse reactions induced by simvastatin atorvastatin used Peru, their clinical implications. Methods: The bibliographic search was carried out PubMed/Medline, Google Scholar...
El objetivo de esta investigación fue realizar una intervención educativa con el propósito potenciar los conocimientos participantes acerca la importancia del cuidado medio ambiente y megadiversidad en país a partir ello, buscar generar conciencia protectora que permee su rol ciudadanos futuros profesionales sus respectivos campos laborales. Este trabajo presentó lógica deductiva, alcance descriptivo enfoque cuantitativo. La muestra incluyó 20 carrera profesional Farmacia Bioquímica...