A5071811930- Ovarian function and disorders
- Circadian rhythm and melatonin
- Growth Hormone and Insulin-like Growth Factors
- Thyroid Disorders and Treatments
- Reproductive Biology and Fertility
- Hormonal and reproductive studies
- Birth, Development, and Health
- Sperm and Testicular Function
- Neurological and metabolic disorders
- Hypothalamic control of reproductive hormones
- Ovarian cancer diagnosis and treatment
- Nitric Oxide and Endothelin Effects
- Transplantation: Methods and Outcomes
- Pancreatic function and diabetes
- Sexual Differentiation and Disorders
- Biomedical Ethics and Regulation
- Digestive system and related health
- Blood Pressure and Hypertension Studies
- Aluminum toxicity and tolerance in plants and animals
- Heart Failure Treatment and Management
- Peripheral Artery Disease Management
- Inflammatory mediators and NSAID effects
- Sleep and related disorders
- Muscle and Compartmental Disorders
- Diet, Metabolism, and Disease
European Gravitational Observatory
2021-2024
Sapienza University of Rome
2011-2024
Hospital Juárez de México
2024
Universidad Nacional Autónoma de México
2024
ASL Roma
2024
Fondazione Cassa di Risparmio Civitavecchia
2021
Policlinico Umberto I
2013
Prefeitura Municipal de Campos dos Goytacazes
2012
Foro Italico University of Rome
1999
University of Padua
1986-1993
Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been matter contention. Since 1990 scientific societies in field human reproduction have tried define pivotal criteria for diagnosis PCOS. The consensus Rotterdam included presence hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology (PCOM), now updated evidence based 2018 2023 International Guideline endorsed by...
Akkermansia muciniphila is a mucin-degrading bacterium of the intestinal niche, exerting beneficial effects on host metabolic profile. Accumulating evidence indicated as promising therapeutic probiotic against disorders such obesity, type 2 diabetes and cardiovascular diseases. However, in specific microenvironments, its excessive enrichment may be not beneficial. Conditions like inflammatory bowel disease (IBD), Salmonella typhimurium infection or post-antibiotic reconstitution benefit from...
The aim of this clinical trial was to evaluate the efficacy seven different ratios between two inositols stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), in therapy polycystic ovary syndrome (PCOS).fifty-six PCOS patients (8 for each group) were treated by oral route using following formulations: DCI alone, 1:3.5; 2.5:1; 5:1; 20:1; 40:1, 80:1 MI/DCI ratio. They received 2 g twice a day 3 months. primary outcome ovulation, secondary included improvement FSH, LH, Sex Hormone...
Background. Hashimoto's thyroiditis (HT), also known as chronic lymphocytic or autoimmune thyroiditis, is the most common form of affecting more than 10% females and 2% males. The present study aims to evaluate beneficial effect a combined treatment, Myo-Inositol plus selenomethionine, on subclinical hypothyroidism. Methods. was designed double-blind randomized controlled trial. Eligible patients were women diagnosed with hypothyroidism having Tg antibodies (TgAb) titer higher 350 IU/mL....
Purpose The combination of lifestyle changes and nutraceuticals, such as inositols, can reduce excess weight, leading to a reduction in insulin resistance normalization the metabolic profile. As such, this study investigated hormonal observed women who were overweight/obese with undergoing hypocaloric Mediterranean diet combined high-dose D-chiro-inositol (DCI) treatment. Methods In total, 48 insulin-resistant between 25 40 years old, body mass index (BMI) 26 32 divided into two groups: both...
Clinical evidences have highlighted the efficacy of myo-inositol and selenium in treatment autoimmune thyroiditis. Aim this study was to further analyze role plus (Myo-Ins-Se) restoring a normal thyroid function Hashimoto’s patients with subclinical hypothyroidism. Eighty-six thyroiditis having thyroid-stimulating hormone (TSH) levels between 3 6 mIU/L, elevated serum antithyroid peroxidase (TPOAb) and/or antithyroglobulin (TgAb), free thyroxine (fT 4 ) triiodothyronine were enrolled study:...
Background: Recent studies reported possible concerns following long-lasting treatments with high doses of D-chiro-inositol in women. However, to date, no clinical trial has investigated or validated these concerns. We addressed this issue both retrospectively and a prospective pilot study. Methods: For the retrospective analysis, we searched our databases for insulin-resistant women who took 1200 mg/day 6 months. In study, enrolled 10 healthy supplement same therapeutic scheme. performed...
The present study was designed to evaluate the effects of endothelin (ET) on rat testicular steroidogenesis in vitro and involvement prostaglandins (PG) extracellular calcium its mechanism action. To this purpose we examined ET-1 ET-3 basal testosterone secretion, influence PGE2 release, interaction with human chorionic gonadotrophin (hCG) interference indomethacin (an inhibitor cyclooxygenase) nifedipine (a calcium-channel blocker) purified Leydig cells. data indicate that stimulate...
To see whether cardiac morphological and functional abnormalities in uraemic patients are determined by high blood pressure or if they an expression of a specific cardiomyopathy.Cross sectional study.City general hospital Italy.35 receiving haemodialysis (17 men, 18 women; mean age 60.3 (11.2); duration dialysis 52 months) were selected from the 64 Venice who dialysis; subjects with diabetes, haemochromatosis, valvar dysfunction, regional dyskinesias, pericarditis excluded. 19 control...
The primary control of dysmetabolic patients is extremely challenging worldwide, with inadequate dietary habits and sporadic physical activity among the key risk factors for metabolic syndrome onset. Nowadays, there no exclusive treatment this condition, considering that preventive measures usually fail, new therapeutic approaches need to be proposed investigated. This present pilot study compared effects diet alone in association a combination myo-inositol d-chiro-inositol their 40:1 ratio,...
DI LUIGI, L., L. GUIDETTI, F. PIGOZZI, C. BALDARI, A. CASINI, M. NORDIO, and ROMANELLI. Acute amino acids supplementation enhances pituitary responsiveness in athletes. Med. Sci. Sports Exerc., Vol. 31, No. 12, pp. 1748–1754, 1999. Purpose The purpose of this study was to determine the effect a mixture on stimulation test (GnRH + CRH) Methods In double blinded counterbalanced experimental protocol, 10 moderately trained male athletes performed 60 min after single oral administration placebo...
The aim of the present study was to evaluate whether arachidonic acid metabolism may play a role on luteinizing hormone (LH) and prolactin (PRL) release directly at pituitary level. To this purpose, exogenous acid, alone or in presence inhibitors cycloxygenase (indomethacin:IND) lipoxygenase pathways (nordihydroguaiaretic acid:NDGA), added perfused rat anterior cells. PGE, PGFα, LH PRL levels eluate were assayed with specific RIA methods. Both PGE PGFα show dose-related response after...