Marie Hargreave

ORCID: 0000-0001-6821-9242
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About
Contact & Profiles
Research Areas
  • Assisted Reproductive Technology and Twin Pregnancy
  • Childhood Cancer Survivors' Quality of Life
  • Acute Lymphoblastic Leukemia research
  • Cancer Risks and Factors
  • Pregnancy and Medication Impact
  • Reproductive Health and Technologies
  • Prenatal Screening and Diagnostics
  • Birth, Development, and Health
  • Reproductive Biology and Fertility
  • Adolescent and Pediatric Healthcare
  • Family Dynamics and Relationships
  • Neonatal Respiratory Health Research
  • Pregnancy and preeclampsia studies
  • Family Support in Illness
  • Reproductive Health and Contraception
  • Autism Spectrum Disorder Research
  • Immunodeficiency and Autoimmune Disorders
  • Reproductive System and Pregnancy
  • Child Welfare and Adoption
  • Gestational Trophoblastic Disease Studies
  • Immunotherapy and Immune Responses
  • Attention Deficit Hyperactivity Disorder
  • Occupational health in dentistry
  • Adrenal Hormones and Disorders
  • Health, psychology, and well-being

Danish Cancer Society
2016-2025

Danish National Institute of Public Health
2007

<h3>Importance</h3> An increasing number of children worldwide are born after the use fertility treatment, although it remains unclear whether treatment affects risk childhood cancer and any associations observed due to specific drugs, procedures, or underlying infertility. <h3>Objective</h3> To examine association between different types treatments in children. <h3>Design, Setting, Participants</h3> A retrospective cohort study based on Danish population-based registry data Infertility...

10.1001/jama.2019.18037 article EN JAMA 2019-12-10

This study uses data from nationwide Danish registries to assess breast cancer risk with continuous use of levonorgestrel-releasing intrauterine systems, accounting for other hormonal exposures.

10.1001/jama.2024.18575 article EN JAMA 2024-10-16

A protective effect of childhood vaccinations on leukemia risk, particularly acute lymphoblastic (ALL), has been hypothesized, though findings are inconsistent. We used a nationwide cohort Danish children born 1997-2018 (n = 1,360,230), to examine associations between and (<20 years) using registry data (follow-up: December 31, 2018). Cox proportional hazard models with age as the underlying time estimated ratios (HRs) for (any, ALL, myeloid [AML], other), comparing vaccinated unvaccinated...

10.1002/ijc.35338 article EN International Journal of Cancer 2025-01-16

Is the risk of hospital admission or outpatient contact for mental disorders increased in children born to women with fertility problems compared without problems? We found an problems. Few studies have investigated after treatment and although some pointed risk, others no association. The inconsistent results may be due methodological constraints many previous studies, including small sample size short follow-up, resulting imprecise estimates lack information on patterns adulthood. This...

10.1093/humrep/dev172 article EN Human Reproduction 2015-07-22

Large population-based studies are needed to examine the effect of maternal use fertility drugs on risk cancer in children, while taking into account underlying infertility. A cohort 123,322 children born Denmark between 1964 and 2006 68,255 women who had been evaluated for infertility was established. We used a case-cohort design calculated hazard ratios (HRs) childhood (0-19 years) young adulthood (20-29 associated with six groups (clomiphene, gonadotropins [i.e., human menopausal...

10.1002/ijc.29235 article EN International Journal of Cancer 2014-09-25

Background: Surveillance of childhood cancer incidence is informative for etiologic research and health policy. However, high-quality data covering several decades virtually complete diagnosis in children sparse.Methods: Incident cases (0–19 years at diagnosis), classified according to Birch Marsden's International Classification Childhood Cancer, first edition (ICCC-1), were identified the Danish Cancer Registry used calculate age-standardized rates (ASRs) estimated annual percentage change...

10.1080/0284186x.2020.1725239 article EN Acta Oncologica 2020-02-12

Abstract Purpose Widespread use of and serious adverse effects associated with analgesics accentuates the need to consider factors related analgesic use. The objective this study was describe continuous regular examine a Methods based on data from two surveys included random sample women men aged 18–45 years general Danish population. Information use, self‐rated health, demographic lifestyle collected using self‐administered questionnaire. A total 28 000 33 were invited participate 22 199...

10.1002/pds.1864 article EN Pharmacoepidemiology and Drug Safety 2009-09-15

Some studies have indicated that children born after fertility treatment a potential risk for cancer, but the results are inconsistent. Furthermore, any negative effects of might be due to underlying infertility rather than procedure itself. In largest cohort study date with information on fertility, we examined whether offspring women problems had higher cancer without problems. The consisted 2,830,054 in Denmark between 1964 and 2006. Of these, 125,844 were evaluated infertility. Cox...

10.1002/ijc.28110 article EN International Journal of Cancer 2013-02-13

Background Childhood cancer is a devastating experience for the family. The objective of current study was to assess impact having child with on parental separation, divorce, and future family planning among families residing in Denmark. Methods authors conducted nationwide cohort using Danish registry data. Parents children diagnosed between 1982 2014 (7066 12,418 case parents) were matched 10 comparison parents cancer‐free per parent (69,993 125,014 parents). We used discrete‐time Cox...

10.1002/cncr.32901 article EN Cancer 2020-05-25

The aim of this study was to investigate whether consumption coffee, tea and caffeine affects the risk primary infertility in women.We selected nulliparous Danish women aged 20-29 years from a prospective cohort retrieved information on coffee questionnaire an interview at enrollment. We assessed women's fertility by linkage Infertility Cohort children vital status Civil Registration System. All 7574 included for analysis were followed date enrollment (1991-1993) until 31 December 2010....

10.1111/aogs.13307 article EN Acta Obstetricia Et Gynecologica Scandinavica 2018-01-24

Having a child with cancer may affect the socioeconomic situation of parents. We aimed to assess impact childhood on parental working status and income identify determinants adverse changes after child's diagnosis by calendar period. conducted nationwide cohort study using Danish registry data. Parents children diagnosed in 1982-2014 (n = 12,418) were matched comparison parents cancer-free 125,014). analysed annual (working/not working) disposable (lowest quintile/not lowest quintile) case...

10.1002/ijc.32867 article EN International Journal of Cancer 2020-01-14

<h3>Importance</h3> The incidence of central nervous system (CNS) tumors in children appears to be increasing, yet few risk factors are established. There is limited information regarding whether maternal hormonal contraception use increases this risk. <h3>Objective</h3> To examine the association between and CNS (&lt;20 years). <h3>Design, Setting, Participants</h3> In nationwide cohort study based on population-based registry data, 1 185 063 born Denmark January 1, 1996, December 31, 2014,...

10.1001/jama.2021.22482 article EN JAMA 2022-01-04

While some studies have indicated that children born following fertility treatment are at an increased risk for insulin resistance and higher blood glucose levels, no study to date has investigated the of type 1 diabetes. In this large population-based cohort we aim assess association between maternal problems diabetes in children.Information on all children, Denmark from 1987 2010, was extracted Civil Registration System linked with Danish Infertility Cohort identify status. Diabetes...

10.1111/aogs.13028 article EN Acta Obstetricia Et Gynecologica Scandinavica 2016-09-28

Having a child diagnosed with cancer is devastating experience that may affect parents' mental health. We aimed to assess the risk of hospital contacts for psychiatric disorders in parents children cancer.We conducted nationwide population-based cohort study using Danish registry data. Parents between 1982 and 2014 (n = 6689 mothers, n 5509 fathers) were matched comparison cancer-free 67 544 55 756 fathers). used Cox proportional hazards models estimate any disorder specific disorders. also...

10.1093/jncics/pkab036 article EN cc-by-nc-nd JNCI Cancer Spectrum 2021-04-07

Studies have suggested increased risks of childhood leukaemia after prenatal exposure to antibiotics, particularly nitrofurantoin. However, these findings may be related the underlying maternal infection. This multinational study aimed investigate association between nitrofurantoin and while accounting for infection.In a population-based cohort children born in Denmark, Finland, Norway or Sweden from 1997 2013, pivmecillinam (active comparator) was ascertained national Prescription...

10.1093/ije/dyab219 article EN cc-by International Journal of Epidemiology 2021-09-16

It has been proposed that childhood vaccinations protect against acute lymphoblastic leukaemia (ALL) in children by modulation of future responses to common infections childhood. However, the available studies provide inconsistent findings, and population-based cohort with longitudinal information on are lacking.In a register-based all born Denmark from 1 January 1990 31 December 2008, followed up until age 15 years or 2009 ( n = 225 404), we evaluated exposure vaccination risk ALL,...

10.1093/ije/dyx052 article EN International Journal of Epidemiology 2017-03-15

Is maternal use of hormonal contraception associated with the development epilepsy in offspring?We found that was a slightly increased risk offspring.Foetal exposure to exogenous hormones has been changes brain development. However, little is known about and offspring.A nationwide cohort all live born children Denmark between 1 January 1998 31 December 2014, followed from day 29 after birth for (first diagnosis or first redeemed prescription anti-epileptic medication) censoring (emigration,...

10.1093/humrep/deab023 article EN Human Reproduction 2021-01-14

Early maternal cancer and fertility treatment each increase the risk for adverse birth outcomes, but joint effect of these outcomes has not yet been reported. Thus, aim was to assess individual on outcomes.This population-based cohort study included 5487 live-born singletons identified in Danish Medical Birth Register (1994-2016) mothers with previous (<40 years) recorded Cancer Registry (1955-2014). We randomly selected 80,262 no <40 years matched by year month. calculated odds ratios (ORs)...

10.1016/j.eclinm.2022.101369 article EN cc-by-nc-nd EClinicalMedicine 2022-04-01
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