A5062947715- Organoselenium and organotellurium chemistry
- Sulfur-Based Synthesis Techniques
- Click Chemistry and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Chemical Synthesis and Reactions
- Computational Drug Discovery Methods
- Biochemical Acid Research Studies
- Nuclear Receptors and Signaling
- Cyclopropane Reaction Mechanisms
- Ferrocene Chemistry and Applications
- Selenium in Biological Systems
- Essential Oils and Antimicrobial Activity
- Organic Chemistry Cycloaddition Reactions
- Synthesis and characterization of novel inorganic/organometallic compounds
- Organometallic Compounds Synthesis and Characterization
- Synthesis and Characterization of Pyrroles
- Organic and Inorganic Chemical Reactions
- Synthesis and biological activity
University of Perugia
2020-2025
Universidade Federal de Pelotas
2017-2022
In recent years, selenium and selenium‐containing compounds have attracted increasing attention due to their fascinating biological activities synthetic versatility. This review aims highlight the advances in chemistry of cyclic structures incorporating this valuable yet rare heteroatom. Special emphasis is given 5‐ 6‐membered rings containing selenium, including combinations with other heteroatoms such as oxygen nitrogen. To provide a comprehensive up‐to‐date overview, we summarized...
We described here our results on the use of thiourea as a ligand in copper catalysed azide-alkyne cycloaddition (CuAAC) 2-azidobenzaldehyde with alkynes. Reactions were performed reacting range terminal alkynes using 10 mol % iodide catalyst, 20 ligand, triethylamine base, DMSO solvent at 100 °C under nitrogen atmosphere. The corresponding 2-(1H-1,2,3-triazoyl)-benzaldehydes (2-TBH) obtained moderated to excellent yields and according experiments, decreases formation side products. compounds...
Abstract Efficient cyclopropanation reactions of aryl or styrylacetonitriles with vinyl selenones under mild conditions were described. By this approach, synthetically challenging 1‐vinylcyclopropane‐1‐carbonitriles accessible in good yields. This methodology features the advantage operational simplicity, broad substrate scope, functional group tolerance, transition‐metal‐free conditions, temperature, and a high level regio‐ diastereo‐control.
The synthesis of 2′-(1,2,3-triazoyl)-acetophenones by a CuAAC using thiourea as ligand, molecular docking and MAO activity analyses were performed.
A new protocol for the synthesis of N-vinyl azoles using vinyl selenones and in presence potassium hydroxide was developed. This reaction proceeded under mild transition metal-free conditions through an addition/elimination cascade process. Both aromatic aliphatic various mono-, bi- tri-cyclic can be tolerated give terminal moderate to high yields. plausible mechanism is also proposed.
The use of renewable feedstocks, which may substitute those derived from petroleum, is currently a great challenge in the chemical and pharmaceutical industries.However, plant essential oils (EOs) that have been studied for their biological activities, such as antioxidant, antimicrobial, antifungal antinociceptive are generally regarded safe additives maintaining microbiological stability foods.EOs mixture natural volatile compounds, predominantly formed during secondary metabolism plants...
Oximes are important intermediates in organic synthesis and they have been used as building blocks many transformations. They the of N-substituted amides by Beckmann rearrangement or production plastics, synthetic fibers, pharmaceutical derivatives. With respect to their biological properties, oximes may act bactericide, insecticide, herbicide, fungicide, with advantage often having low toxicity. The traditional method prepare is reaction a carbonyl compound an excess hydroxylamine...