A5022973496- Vagus Nerve Stimulation Research
- EEG and Brain-Computer Interfaces
- Epilepsy research and treatment
- Ultrasound and Hyperthermia Applications
- Neuroscience and Neural Engineering
- Advanced MRI Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Neurological disorders and treatments
- Neuroscience and Neuropharmacology Research
- Neurology and Historical Studies
- Heart Rate Variability and Autonomic Control
- Pain Management and Treatment
- Neural and Behavioral Psychology Studies
- Photoreceptor and optogenetics research
- Atomic and Subatomic Physics Research
- Mitochondrial Function and Pathology
Ghent University
2025
Ghent University Hospital
2021-2024
Eindhoven University of Technology
2023
Abstract It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular (taVNS) gained interest as a non-invasive alternative to improve cognition. In this prospective randomized cross-over study, we investigated the effect of both invasive VNS and taVNS on verbal performance 15 patients with drug-resistant epilepsy. All conducted paradigm 3 conditions: ON, OFF (3-period 3-treatment study design). For each...
The locus coeruleus (LC)-noradrenaline (NA) system plays a crucial role in modulating neuronal excitability and plasticity. In epilepsy, the LC-NA an important regulating seizure thresholds severity, with elevated NA release mediating seizure-suppressing effects of vagus nerve stimulation (VNS). We investigated whether chemogenetic LC activation is able to increase hippocampal affect electrophysiology anesthetized rats. 22 male Sprague-Dawley rats were injected viral vector AAV9-hSyn-NE2m...
BackgroundTranscranial direct current stimulation (tDCS) is used to modulate neuronal activity, but the exact mechanism of action (MOA) unclear. This study investigates tDCS-induced modulation corticospinal excitability and underlying MOA. By anesthetizing scalp before applying tDCS by stimulating cheeks, we investigated whether peripheral and/or cranial nerves contributes effects on excitability.Materials MethodsIn a randomized cross-over study, four experimental conditions with anodal were...
Abstract Background and purpose Neurological disorders constitute a significant portion of the global disease burden, affecting >30% world's population. This prevalence poses substantial threat to health in foreseeable future. A lack awareness regarding this high burden neurological diseases has led their underrecognition, underappreciation, insufficient funding. Establishing strategic comprehensive research agenda for brain‐related studies is crucial step towards aligning objectives...
Abstract Introduction: It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular (taVNS) gained interest as a non-invasive alternative to improve cognition. In this prospective randomized cross-over study, we investigated the effect of both invasive VNS and taVNS on verbal performance 15 drug-resistant Methods All patients conducted paradigm 3 conditions: ON, OFF taVNS. For each condition, memorized 21...
In this prospective, randomized, cross-over study, we investigated the effect of both invasive vagus nerve stimulation (VNS) and transcutaneous auricular (tavNS) on verbal memory performance in epilepsy patients.