A5009531136- EEG and Brain-Computer Interfaces
- Vagus Nerve Stimulation Research
- Neurological disorders and treatments
- Epilepsy research and treatment
- Neuroscience and Neural Engineering
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Advanced MRI Techniques and Applications
- Heart Rate Variability and Autonomic Control
- Neuroscience and Neuropharmacology Research
- Functional Brain Connectivity Studies
- Pharmacological Effects and Toxicity Studies
- Diet and metabolism studies
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Neurosurgical Procedures and Complications
- Neurological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Human-Animal Interaction Studies
- Biochemical Analysis and Sensing Techniques
- Migraine and Headache Studies
- Gastroesophageal reflux and treatments
- Neurobiology of Language and Bilingualism
- Mitochondrial Function and Pathology
Ghent University Hospital
2015-2025
Ghent University
2007-2024
Université Lille Nord de France
2011-2013
Centre Hospitalier Universitaire de Lille
2011-2013
Neuromod (Ireland)
2006
Dartmouth–Hitchcock Medical Center
2004
Heidelberg University
1993
Summary: Purpose: This pilot study prospectively evaluated the efficacy of long‐term deep brain stimulation (DBS) in medial temporal lobe (MTL) structures patients with MTL epilepsy. Methods: Twelve consecutive refractory epilepsy were included this study. The protocol invasive video‐EEG monitoring for ictal‐onset localization and evaluation subsequent zone. Side effects changes seizure frequency carefully monitored. Results: Ten 12 underwent DBS. Two selective amygdalohippocampectomy. After...
The classification and pathological mechanisms of many central nervous system inflammatory diseases remain uncertain. In this article we report eight patients with a clinically radiologically distinct pontine-predominant encephalomyelitis have named 'chronic lymphocytic inflammation pontine perivascular enhancement responsive to steroids' (CLIPPERS). were assessed clinically, pathologically at Mayo Clinic, USA Ghent University Hospital, Belgium from 1999 2009. Median follow-up duration...
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for medically refractory epilepsy. In this study, we measured VNS-induced changes in hippocampal neurotransmitter levels and determined their potential involvement the anticonvulsive action of VNS, to elucidate mechanism responsible seizure suppressing effect VNS animal model limbic seizures. We used vivo intracerebral microdialysis measure extracellular concentrations noradrenaline, dopamine, serotonin GABA freely moving,...
<h3>Objective:</h3> In patients with spontaneous intracerebral hemorrhage (ICH), the occurrence of early seizures (ES) may be a prognostic marker. Therefore, we aimed to identify incidence, associated factors, and influence on outcome ES in ICH. <h3>Methods:</h3> Between November 2004 March 2009, prospectively recruited 562 consecutive adults ICH (Prognosis InTra-Cerebral Hemorrhage cohort). Patients previous (n = 40) were excluded. defined as occurring within 7 days stroke onset, their...
In this study, we present long-term results from patients with medial temporal lobe (MTL) epilepsy treated deep brain stimulation (DBS). Since 2001, 11 (8M) refractory MTL underwent DBS. When unilateral DBS failed to decrease seizures by > 90%, a switch bilateral was proposed. After mean follow-up of 8.5 years (range: 67-120 months), 6/11 had ≥ 90% seizure frequency reduction 3/6 seizure-free for 3 years; three 40%-70% and two < 30% reduction. 3/5 switching further improved outcome. Uni- or...
To identify incidence and predictors of late seizures (LS, occurring >1 week stroke) in a cohort patients with intracerebral hemorrhage (ICH).Prospective consecutive adults spontaneous ICH. Incidence were identified Cox regression. We included multivariate analyses on MRI biomarkers (global cortical atrophy, leukoaraiosis, brain microbleeds).Our study population consisted 325 patients: 54% men, median age 70 years (interquartile range, 58-79). During 778 person-years follow-up, the rate was...
Dysphagia, dysarthria and aphasia are common symptoms following acute stroke; however, limited data available from recent prospective clinical trials. The aim of this study was to determine the incidence associated factors dysphagia, a first ischaemic stroke in patients admitted comprehensive center.All Stroke Unit Ghent University Hospital within 48 h after symptom onset were enrolled between March 2018 October 2019. Dysphagia communication screenings performed 3 days admission. When and/or...
Abstract It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular (taVNS) gained interest as a non-invasive alternative to improve cognition. In this prospective randomized cross-over study, we investigated the effect of both invasive VNS and taVNS on verbal performance 15 patients with drug-resistant epilepsy. All conducted paradigm 3 conditions: ON, OFF (3-period 3-treatment study design). For each...
Vagus nerve stimulation (VNS) is an alternative treatment for medically or surgically refractory epilepsy. The long-term efficacy and safety of VNS were evaluated in a large patient series at Ghent University Hospital Dartmouth-Hitchcock Medical Center. Between March 1995 February 2003, seizure frequency type as well prescribed antiepileptic drugs side effects prospectively assessed 131 patients treated with either center. Patients minimum follow-up duration 6 months included the analysis. A...
To this day, metabolic brain connectivity is mostly studied on a group level through the acquisition of static positron emission tomography (PET) data multiple subjects. Our research groups are currently studying changes in across time points following an intracerebral hemorrhage intrasubject rats. investigate connectivity, temporal information tracer uptake different regions required, which can be achieved dynamic PET. In publication, we give detailed description our and analysis protocol....